This document provides an overview of the organizational structure of NASA's Human Exploration and Operations Mission Directorate. It outlines the directorate's divisions including Space Operations, Exploration Systems Development, Human Spaceflight Capabilities, ISS, Commercial Spaceflight, and Advanced Exploration Systems. It also summarizes common capabilities needed for exploration like ground operations, in-space propulsion, environmental control life support systems, and radiation protection. Finally, it lists cross-cutting technologies, research areas, and ongoing technology developments important for human exploration.