Ultrasonography, also known as B-scan, was first used in ophthalmology in the 1940s. It uses high frequency sound waves to generate images of the inside of the eye. B-scans can be used to evaluate conditions like tumors, retinal detachments, and vitreous opacities. The document discusses the history, physics, principles and various applications of B-scan ultrasonography for examining the eye. Key aspects covered include probe orientation, scan types, interpretation of echogenicity and advantages in providing a non-invasive evaluation of intraocular structures.