This document analyzes pharmaceutical sales force management strategies. It finds that returns on promotional investment have declined 24% from 1998-2001, as companies focus on maintaining large sales forces without improving effectiveness. It recommends that companies rethink detailing strategies to halt this decline. The analysis also finds that sales force size and structure should evolve throughout a product's lifecycle to maximize revenue potential. It provides sales force benchmarks for seven countries/regions and recommendations for optimizing sales force size, structure, and effectiveness across different markets and stages of the product lifecycle.