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Calsi soya ppt
 Bone and its component
 Bone Homeostasis
 Bone remodeling
 Definition and classification of osteoporosis
 Prevalence
 Risk Factors and presentation
 Diagnosis
 Consequences
 Management principle
 Treatment goal
 Organic Component:
 protein collagen & specialized
cells called osteoclasts,
osteoblasts, and osteocytes
 Inorganic component:
 Mainly as calcium phosphate,
in the form of Hydroxyapatite
 Bone Homeostasis:
 the situation when the body
requires and achieves an equal
amount of bone resorption and
bone formation
 the amount of bone eroded by
osteoclasts is equal to the
amount of bone produced by
osteoblasts, thereby producing
a stable net mass of bone in the
body
Homeostasis
 The combined processes of breaking down bone and
building new bone are called Bone Remodeling.
 It is the body’s way of maintaining bone homeostasis.
 5 Stages:
 Initiation,
 Resorption,
 Reversal,
 Bone formation and
 Completion of remodeling.
Osteoclast precursor cells are attracted to a bone site and
penetrate the bone lining cells. These osteoclast precursor cells
then form activated osteoclasts that align themselves in direct
contact with mineralized bone matrix.
The osteoclasts erode a cavity by removing mineral and organic
components from the bone. The osteoclasts eventually die. This
completes the resorption phase.
Cells of unknown origin prepare the bone surface for new bone
formation by smoothing the surface of the cavity and
depositing a thin layer of a cement-like substance.
Cells of unknown origin prepare the bone surface for new bone
formation by smoothing the surface of the cavity and
depositing a thin layer of a cement-like substance.
The lining cells rest on the bone surface until the next cycle of
bone remodeling begins.
Some osteoblasts become osteocytes.
Calsi soya ppt
National Osteoporosis Foundation:
 a disease characterized by low bone
mass an micro-architectural
deterioration of bone tissue, leading
to bone fragility and an increased
susceptibility to fractures.”
World Health Organization :
 bone mineral density T-score greater
than –2.5 standard deviations from
the mean peak adult bone mass (ie. a
woman in her 30’s).”
 Primary osteoporosis
• Juvenile osteoporosis.
• Idiopathic osteoporosis
• Postmenopausal
osteoporosis
• Age-related, or senile,
osteoporosis
• Secondary osteoporosis
• Congenital
• Diet
• Drugs
• Endocrine disorder
• Other Systemic Disorder
Building & Losing bone with years
“Osteoporosis, the silent thief of your bone”
Worldwide, over age of 50
 1 in 3 women / 1 in 8 men have osteoporosis.
 80 % of those suffering from osteoporosis are women.
 Affects 75 million persons in the US, Europe and Japan.
 Over 50% of women aged 50 years or older and 20% of men
will suffer an osteoporosis-related fracture within their
remaining lifetime
 Being female
 Older age
 Family history of osteoporosis or broken bones
 Being small and thin
 History of broken bones
 Low sex hormones
• Low estrogen levels in women, including menopause
• Missing periods (amenorrhea)
• Low levels of testosterone and estrogen in men
 Diet
• Low calcium intake
• Low vitamin D intake
• Excessive intake of protein,
sodium and caffeine
 Inactive lifestyle
 Smoking , Alcohol abuse
 Certain medications
• steroid , anticonvulsants etc
 Certain diseases
• anorexia nervosa, rheumatoid
arthritis, gastrointestinal diseases
and others
 People may not know that they have
osteoporosis until they break a bone.
 Vertebral (spinal) fractures may
initially be felt or seen in the form of
 Persistent, unexplained back pain
 Loss of height
 Spinal deformities such as
kyphosis or stooped posture.
 Bone mineral density (BMD) tests can measure bone
density in various sites of the body.
 BMD test is done to diagnose and predict fracture risk
and to monitor therapy.
 For patients on pharmacotherapy, it is typically performed
2 years after initiating therapy and every 2 years
thereafter; however, more frequent testing may be
warranted in certain clinical situations.
 Dual-energy X-ray Absorptiometry (DXA) Scan
• “Gold-standard” for BMD measurement.
• Measures “central” or “axial” skeletal sites: spine and
hip.
• May measure other sites: total body and forearm.
• Validated in many clinical trials.
• Available in Bangladesh.
 Dual-energy X-ray Absorptiometry (DXA) Scan
Classification T-score
Normal -1 or greater
Osteopenia Between -1 and -2.5
Osteoporosis -2.5 or less
Severe Osteoporosis
-2.5 or less
and fragility fracture
FRACTURE ,
The most serious complication of
Osteoporosis that leads to
 Increased morbidity
 Increased mortality
 Decreased quality of life
Wrist fracture
men 1 in 40 (2.5%)
women 1 in 6 (16%)
Spinal fracture
men 1 in 20 (5%)
women 1 in 6 (16%)
Hip fracture
men 1 in 17 (6%)
women 1 in 6 (17.5%)
Decreased fracture risk
Life style modification Therapeutic Intervention
• Minimizing risk factors Slowing/stopping
bone loss
• Minimizing factors that
Contribute to fall
Maintaining or increasing
bone density and strength
Maintaining or improving
bone microarchitecture
 Supplements
 such as which maintain bone mass Calcium, Vitamin D
 Anti-resorptive agents
 which inhibit bone resorption Bisphosphonates
 Anabolic agents,
 which stimulate bone formation and, in turn, increase
bone mass.
 Prevent further bone loss
 Increase or at least stabilize bone density
 Prevent further fractures
 Relieve deformity (e.g., kyphoplasty)
 Relieve pain
 Increase level of physical functioning
 Increase quality of life
The Perfect Bone
Supplement!
Calsi-soya is an all-natural health
supplement claimed to prevent
you from osteoporosis, which
happens due to bone fractures
and other bone related issues.
Calsi-soya is also used as a
supplement to maintain bone
health.
• It supports bone health by increasing
bone density.
• Recover and helps to regain bone mass
which is very important for healthy
bone.
• Prevent Osteoporosis.
• Provide and supply bones with sufficient
vitamins and minerals.
• Boost and makes strong Bone function,
so Bones will work efficiently.
Calsi soya ppt
Why Calci-Soya Balance supplement?
Vitamin K, calcium, zinc, magnesium and manganese: ossification and
bone healing
Vitamin D3, boron, lysine, magnesium: reducing urinary calcium
excretion
Manganese and soy polysaccharides: calcium sediment in bone tissues
Copper and lysine: collagen synthesis
Contains calcium carbonate: most absorbable form of calcium
Only calcium + vitamin D3 supplement containing soy isoflavone:
effective in improving menopause symptoms especially flushing,
nocturnal perspiration and bone mass density reduction
Produced under global standard certification of cGMP
Produced and packed in US
Calci-soya Balance
First choice for standing against the silent disease
Promotes bone and joint health
Reduces risk of osteoporosis
Improves osteoporosis through:
Increasing bone minerals
concentration
Bone healing and synthesis
Reduces pain
Improves healing process in stress
fractures
Improves menopause symptoms
including flushing and nocturnal
perspiration
Grow old strong
• Calci soya is not just a calcium
supplement; It is everything bone needs
• Administration: one soft gel per day with
a meal
• Do not deprive your bones from minerals.
Using supplements is not a necessity for
people suffering from osteoporosis. If you
care about this disease earlier, you can
easily prevent it with nutrition and
sporting. It is never late for improving
your bones conditions. Ossification is
possible even in elderly women.
Risk factors for osteoporosis
Hormone
deficiency
such as
estrogen
in women
and
androgen
in men
Overusing
some
drugs
Physical
inactivity
Thyroid
gland
malfuncti
ons
Bone
cancer
and some
inherited
genetic
conditions
Insufficient
calcium
and
vitamin
D3 intake
Soy isoflavone: effective in preventing
osteoporosis and reducing menopause
• Possesses estrogenic properties
and prevents osteoporosis
• Prevents decline in mineral
concentration in bone mass tissue
• Improves complications caused by
menopause including flushing,
nocturnal perspiration and vaginal
dryness
• Proper replacement for HTR
(hormonal treatment
replacement) with no side effects
Calcium: most essential element for
ossification
• Human body needs calcium in ossification process.
• Calcium prevents bone decomposition in menopause
ladies.
• Calcium carbonate; a calcium form with high
absorption abilities
• Calcium carbonate has 40% absorbable calcium;
whereas has 21% in calcium citrate.
Vitamin D; increasing calcium and
phosphorous absorption
• Increases calcium absorption
• Increases minerals concentration in bone mass tissue
• Vitamin D and calcium deficiency is a main risk factor
of osteoporosis. It is because low calcium levels
increase parathyroid functions. Parathyroid hormone
increases bone decomposition and therefore
increases number and activity of osteoclasts which
absorb calcium from bone tissue.
Zinc; important element in vitamin D
activities:
• Improve biochemical activities of zinc
• Increases osteoblasts differentiation and
synthesis of bone tissues proteins
• Prevents calcium resorption from bone
tissue
• Increases mineral concentration in bone
mass tissue
• Increases bone mass density
• Improves fracture healing rate in
conditions such as aging, calcium and
vitamin D deficiency, estrogen deficiency
and diabetes
• Zinc deficiency can decrease osteoblasts’
activities and collagen synthesis. It also
can delay and slow down bone mass
growth.
L-lysine; effective in collagen synthesis
• Increase calcium absorption
in digestive tract and
reduces urinary calcium
excretion
• Improves collagen synthesis
(collagen is 25% of total
body protein and is essential
for bones and other tissues)
Magnesium:Increases calcium
absorption and metabolisms
Is essential for transforming
vitamin D to its active form
• Induces thyroid gland into
calcitonin secretion (which in
turn protects bone tissue)
• Improves parathyroid gland
modification and prevents
bone tissue decomposition
Copper; reducing calcium resorption
from bones
• Improves protein synthesis
necessary for connective and
bone tissue
• Improves mechanical
resistance of collagen in bone
tissue
• Prevents minerals resorption
to bloodstream
Manganese; increasing mineral
concentration in bone tissue
• Increases bone minerals
• Increases protein and cartilage
syntheses
• Manganese deficiency can
reduce calcium sediment in bone
tissues and increase fracture risk
• Manganese deficiency can
reduce mineral concentration in
bone tissue and increase bone
decomposition
Boron; reducing calcium excretion
• Human body needs boron for different
ossification metabolisms including
calcium, magnesium, vitamin D, estrogen
and possibly testosterone metabolism.
Generally studies show boron improves
minerals concentration and estrogen
levels; especially in women intake
insufficient magnesium.
• Role of boron in bone health
• Prevents minerals concentration
reduction
• Prevents calcium excretion in women
during menopause
• Improves calcium metabolism
Vitamin K
• Improves calcium absorption in
bone mass tissue
• Improving bio-activating proteins
responsible in ossification
metabolisms
• Improving mineral concentration in
bone mass tissue
• Improving bone synthesis and
healing process
http://www.sciencedirect.com/science/article/pii/S0140673607613154
http://www.emedicinehealth.com/osteoporosis/page2_em.htm
http://jn.nutrition.org/content/132/7/2048.full.pdf+html
http://www.pharmaceutical-
journal.com/libres/pdf/articles/pj_20051015_soy.pdf
http://umm.edu/health/medical/altmed/supplement/calcium
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621390
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509509
http://drtorihudson.com/articles/osteoporosis-strategies-for-prevention-
and-management/
http://link.springer.com/article/10.1007/s11010-009-0358-0#page-1
http://link.springer.com/article/10.1007/s774-002-8445-y#page-1
http://www.naturalhealthadvisory.com/daily/osteoporosis-prevention-
and-treatment/natural-treatment-for-osteoporosis-%E2%80%93-how-
body-building-amino-acids-can-help-the-body-build-strong-bones
www.betterbones.com/bonenutrition/20keybonenutrients.pdf
http://ajcn.nutrition.org/content/61/2/341.full.pdf+html
• This Product works for men
and
women alike.
• The complete list of ingredients
are
listed online.
• All Ingredients used are backed
by
clinical studies.
• Comparatively affordable.
• There are lots of positive user
reviews.
I have been taking Calsi-soya for about two years and my
osteoporosis is improved, nails are not chipping, and my level test
scores are good. I highly recommend it. The price is very
competitive. By Bronxirishboy, USA
I have a family history of osteoporosis, so I knew that I needed to do
something to help overcome this issue. I chose Calsi-soya because
of the way that it provided a complete way to fight against bone
loss, and I've never regretted my choice. I've been taking Calsi-soya
for several years now, and I positively love it.
By Jessie Smith, CA
Hitting menopause was definitely not an easy time for me. Between
the mood swings and the physical changes, I felt frustrated with
myself much of the time. However, one positive change that I made
during that time was to start taking Calsi-soya to help improve my
bone density. Calsi-soya has helped me to keep my bones healthy
and strong. By Lisa Henry, Florida
Generally, Both Men and Women are at a risk of Bone Loss,
for them regular use of Calsi-soya recommended.
The person, who has calcium deficiency, must take
Calsi-soya for Recoupment.
Dosage:
Take 1 tablets daily with food
For Further info visit:
These types of Bone supplement are vital for the individuals who are
suffering with osteoporosis or any bone ailments. As this is a bone
supplement, it supplies all vital an important
vitamins and minerals to bones to make them
healthy and promote efficient working.
If this product used regularly, it will
improve Bone mass Density and Prevent
future Degeneration.

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Calsi soya ppt

  • 2.  Bone and its component  Bone Homeostasis  Bone remodeling  Definition and classification of osteoporosis  Prevalence  Risk Factors and presentation  Diagnosis  Consequences  Management principle  Treatment goal
  • 3.  Organic Component:  protein collagen & specialized cells called osteoclasts, osteoblasts, and osteocytes  Inorganic component:  Mainly as calcium phosphate, in the form of Hydroxyapatite
  • 4.  Bone Homeostasis:  the situation when the body requires and achieves an equal amount of bone resorption and bone formation  the amount of bone eroded by osteoclasts is equal to the amount of bone produced by osteoblasts, thereby producing a stable net mass of bone in the body Homeostasis
  • 5.  The combined processes of breaking down bone and building new bone are called Bone Remodeling.  It is the body’s way of maintaining bone homeostasis.  5 Stages:  Initiation,  Resorption,  Reversal,  Bone formation and  Completion of remodeling.
  • 6. Osteoclast precursor cells are attracted to a bone site and penetrate the bone lining cells. These osteoclast precursor cells then form activated osteoclasts that align themselves in direct contact with mineralized bone matrix.
  • 7. The osteoclasts erode a cavity by removing mineral and organic components from the bone. The osteoclasts eventually die. This completes the resorption phase.
  • 8. Cells of unknown origin prepare the bone surface for new bone formation by smoothing the surface of the cavity and depositing a thin layer of a cement-like substance.
  • 9. Cells of unknown origin prepare the bone surface for new bone formation by smoothing the surface of the cavity and depositing a thin layer of a cement-like substance.
  • 10. The lining cells rest on the bone surface until the next cycle of bone remodeling begins. Some osteoblasts become osteocytes.
  • 12. National Osteoporosis Foundation:  a disease characterized by low bone mass an micro-architectural deterioration of bone tissue, leading to bone fragility and an increased susceptibility to fractures.” World Health Organization :  bone mineral density T-score greater than –2.5 standard deviations from the mean peak adult bone mass (ie. a woman in her 30’s).”
  • 13.  Primary osteoporosis • Juvenile osteoporosis. • Idiopathic osteoporosis • Postmenopausal osteoporosis • Age-related, or senile, osteoporosis • Secondary osteoporosis • Congenital • Diet • Drugs • Endocrine disorder • Other Systemic Disorder
  • 14. Building & Losing bone with years
  • 15. “Osteoporosis, the silent thief of your bone”
  • 16. Worldwide, over age of 50  1 in 3 women / 1 in 8 men have osteoporosis.  80 % of those suffering from osteoporosis are women.  Affects 75 million persons in the US, Europe and Japan.  Over 50% of women aged 50 years or older and 20% of men will suffer an osteoporosis-related fracture within their remaining lifetime
  • 17.  Being female  Older age  Family history of osteoporosis or broken bones  Being small and thin  History of broken bones  Low sex hormones • Low estrogen levels in women, including menopause • Missing periods (amenorrhea) • Low levels of testosterone and estrogen in men
  • 18.  Diet • Low calcium intake • Low vitamin D intake • Excessive intake of protein, sodium and caffeine  Inactive lifestyle  Smoking , Alcohol abuse  Certain medications • steroid , anticonvulsants etc  Certain diseases • anorexia nervosa, rheumatoid arthritis, gastrointestinal diseases and others
  • 19.  People may not know that they have osteoporosis until they break a bone.  Vertebral (spinal) fractures may initially be felt or seen in the form of  Persistent, unexplained back pain  Loss of height  Spinal deformities such as kyphosis or stooped posture.
  • 20.  Bone mineral density (BMD) tests can measure bone density in various sites of the body.  BMD test is done to diagnose and predict fracture risk and to monitor therapy.  For patients on pharmacotherapy, it is typically performed 2 years after initiating therapy and every 2 years thereafter; however, more frequent testing may be warranted in certain clinical situations.
  • 21.  Dual-energy X-ray Absorptiometry (DXA) Scan • “Gold-standard” for BMD measurement. • Measures “central” or “axial” skeletal sites: spine and hip. • May measure other sites: total body and forearm. • Validated in many clinical trials. • Available in Bangladesh.
  • 22.  Dual-energy X-ray Absorptiometry (DXA) Scan Classification T-score Normal -1 or greater Osteopenia Between -1 and -2.5 Osteoporosis -2.5 or less Severe Osteoporosis -2.5 or less and fragility fracture
  • 23. FRACTURE , The most serious complication of Osteoporosis that leads to  Increased morbidity  Increased mortality  Decreased quality of life
  • 24. Wrist fracture men 1 in 40 (2.5%) women 1 in 6 (16%) Spinal fracture men 1 in 20 (5%) women 1 in 6 (16%) Hip fracture men 1 in 17 (6%) women 1 in 6 (17.5%)
  • 25. Decreased fracture risk Life style modification Therapeutic Intervention • Minimizing risk factors Slowing/stopping bone loss • Minimizing factors that Contribute to fall Maintaining or increasing bone density and strength Maintaining or improving bone microarchitecture
  • 26.  Supplements  such as which maintain bone mass Calcium, Vitamin D  Anti-resorptive agents  which inhibit bone resorption Bisphosphonates  Anabolic agents,  which stimulate bone formation and, in turn, increase bone mass.
  • 27.  Prevent further bone loss  Increase or at least stabilize bone density  Prevent further fractures  Relieve deformity (e.g., kyphoplasty)  Relieve pain  Increase level of physical functioning  Increase quality of life
  • 29. Calsi-soya is an all-natural health supplement claimed to prevent you from osteoporosis, which happens due to bone fractures and other bone related issues. Calsi-soya is also used as a supplement to maintain bone health.
  • 30. • It supports bone health by increasing bone density. • Recover and helps to regain bone mass which is very important for healthy bone. • Prevent Osteoporosis. • Provide and supply bones with sufficient vitamins and minerals. • Boost and makes strong Bone function, so Bones will work efficiently.
  • 32. Why Calci-Soya Balance supplement? Vitamin K, calcium, zinc, magnesium and manganese: ossification and bone healing Vitamin D3, boron, lysine, magnesium: reducing urinary calcium excretion Manganese and soy polysaccharides: calcium sediment in bone tissues Copper and lysine: collagen synthesis Contains calcium carbonate: most absorbable form of calcium Only calcium + vitamin D3 supplement containing soy isoflavone: effective in improving menopause symptoms especially flushing, nocturnal perspiration and bone mass density reduction Produced under global standard certification of cGMP Produced and packed in US
  • 33. Calci-soya Balance First choice for standing against the silent disease Promotes bone and joint health Reduces risk of osteoporosis Improves osteoporosis through: Increasing bone minerals concentration Bone healing and synthesis Reduces pain Improves healing process in stress fractures Improves menopause symptoms including flushing and nocturnal perspiration
  • 34. Grow old strong • Calci soya is not just a calcium supplement; It is everything bone needs • Administration: one soft gel per day with a meal • Do not deprive your bones from minerals. Using supplements is not a necessity for people suffering from osteoporosis. If you care about this disease earlier, you can easily prevent it with nutrition and sporting. It is never late for improving your bones conditions. Ossification is possible even in elderly women.
  • 35. Risk factors for osteoporosis Hormone deficiency such as estrogen in women and androgen in men Overusing some drugs Physical inactivity Thyroid gland malfuncti ons Bone cancer and some inherited genetic conditions Insufficient calcium and vitamin D3 intake
  • 36. Soy isoflavone: effective in preventing osteoporosis and reducing menopause • Possesses estrogenic properties and prevents osteoporosis • Prevents decline in mineral concentration in bone mass tissue • Improves complications caused by menopause including flushing, nocturnal perspiration and vaginal dryness • Proper replacement for HTR (hormonal treatment replacement) with no side effects
  • 37. Calcium: most essential element for ossification • Human body needs calcium in ossification process. • Calcium prevents bone decomposition in menopause ladies. • Calcium carbonate; a calcium form with high absorption abilities • Calcium carbonate has 40% absorbable calcium; whereas has 21% in calcium citrate.
  • 38. Vitamin D; increasing calcium and phosphorous absorption • Increases calcium absorption • Increases minerals concentration in bone mass tissue • Vitamin D and calcium deficiency is a main risk factor of osteoporosis. It is because low calcium levels increase parathyroid functions. Parathyroid hormone increases bone decomposition and therefore increases number and activity of osteoclasts which absorb calcium from bone tissue.
  • 39. Zinc; important element in vitamin D activities: • Improve biochemical activities of zinc • Increases osteoblasts differentiation and synthesis of bone tissues proteins • Prevents calcium resorption from bone tissue • Increases mineral concentration in bone mass tissue • Increases bone mass density • Improves fracture healing rate in conditions such as aging, calcium and vitamin D deficiency, estrogen deficiency and diabetes • Zinc deficiency can decrease osteoblasts’ activities and collagen synthesis. It also can delay and slow down bone mass growth.
  • 40. L-lysine; effective in collagen synthesis • Increase calcium absorption in digestive tract and reduces urinary calcium excretion • Improves collagen synthesis (collagen is 25% of total body protein and is essential for bones and other tissues)
  • 41. Magnesium:Increases calcium absorption and metabolisms Is essential for transforming vitamin D to its active form • Induces thyroid gland into calcitonin secretion (which in turn protects bone tissue) • Improves parathyroid gland modification and prevents bone tissue decomposition
  • 42. Copper; reducing calcium resorption from bones • Improves protein synthesis necessary for connective and bone tissue • Improves mechanical resistance of collagen in bone tissue • Prevents minerals resorption to bloodstream
  • 43. Manganese; increasing mineral concentration in bone tissue • Increases bone minerals • Increases protein and cartilage syntheses • Manganese deficiency can reduce calcium sediment in bone tissues and increase fracture risk • Manganese deficiency can reduce mineral concentration in bone tissue and increase bone decomposition
  • 44. Boron; reducing calcium excretion • Human body needs boron for different ossification metabolisms including calcium, magnesium, vitamin D, estrogen and possibly testosterone metabolism. Generally studies show boron improves minerals concentration and estrogen levels; especially in women intake insufficient magnesium. • Role of boron in bone health • Prevents minerals concentration reduction • Prevents calcium excretion in women during menopause • Improves calcium metabolism
  • 45. Vitamin K • Improves calcium absorption in bone mass tissue • Improving bio-activating proteins responsible in ossification metabolisms • Improving mineral concentration in bone mass tissue • Improving bone synthesis and healing process
  • 46. http://www.sciencedirect.com/science/article/pii/S0140673607613154 http://www.emedicinehealth.com/osteoporosis/page2_em.htm http://jn.nutrition.org/content/132/7/2048.full.pdf+html http://www.pharmaceutical- journal.com/libres/pdf/articles/pj_20051015_soy.pdf http://umm.edu/health/medical/altmed/supplement/calcium http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2621390 http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509509 http://drtorihudson.com/articles/osteoporosis-strategies-for-prevention- and-management/ http://link.springer.com/article/10.1007/s11010-009-0358-0#page-1 http://link.springer.com/article/10.1007/s774-002-8445-y#page-1 http://www.naturalhealthadvisory.com/daily/osteoporosis-prevention- and-treatment/natural-treatment-for-osteoporosis-%E2%80%93-how- body-building-amino-acids-can-help-the-body-build-strong-bones www.betterbones.com/bonenutrition/20keybonenutrients.pdf http://ajcn.nutrition.org/content/61/2/341.full.pdf+html
  • 47. • This Product works for men and women alike. • The complete list of ingredients are listed online. • All Ingredients used are backed by clinical studies. • Comparatively affordable. • There are lots of positive user reviews.
  • 48. I have been taking Calsi-soya for about two years and my osteoporosis is improved, nails are not chipping, and my level test scores are good. I highly recommend it. The price is very competitive. By Bronxirishboy, USA I have a family history of osteoporosis, so I knew that I needed to do something to help overcome this issue. I chose Calsi-soya because of the way that it provided a complete way to fight against bone loss, and I've never regretted my choice. I've been taking Calsi-soya for several years now, and I positively love it. By Jessie Smith, CA Hitting menopause was definitely not an easy time for me. Between the mood swings and the physical changes, I felt frustrated with myself much of the time. However, one positive change that I made during that time was to start taking Calsi-soya to help improve my bone density. Calsi-soya has helped me to keep my bones healthy and strong. By Lisa Henry, Florida
  • 49. Generally, Both Men and Women are at a risk of Bone Loss, for them regular use of Calsi-soya recommended. The person, who has calcium deficiency, must take Calsi-soya for Recoupment. Dosage: Take 1 tablets daily with food
  • 50. For Further info visit: These types of Bone supplement are vital for the individuals who are suffering with osteoporosis or any bone ailments. As this is a bone supplement, it supplies all vital an important vitamins and minerals to bones to make them healthy and promote efficient working. If this product used regularly, it will improve Bone mass Density and Prevent future Degeneration.