This chapter discusses food safety and technology. It outlines the major causes of foodborne illness, which include viruses, bacteria, parasites, toxins, and fungi. Salmonella and norovirus are responsible for many cases of foodborne illness each year. The chapter also discusses methods for preventing foodborne illness, such as proper cleaning, separating foods to avoid cross-contamination, cooking foods thoroughly, and refrigerating foods at the proper temperatures. Additionally, it covers food preservation techniques including canning, pasteurization, and irradiation. The use of additives, genetic modification, pesticides, and antibiotics in food production is addressed, as well as their impact on food safety. Finally, the chapter looks at the rising food movement and