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EXCRETION
Chapter 13
Chapter 13.1- EXCRETION IN HUMANS IGCSE BIO
Have you ever had bird
dropping land on you?
 Reptiles and birds
 Less water-wasting process for dealing
with their bodies' ammonia
 Instead of ammonia to urea, they convert
it to uric acid
 Excreted as a white paste or even a dry,
white powder
 Through cloacae
Terms you should know
 Cortex
 Medulla
 Pelvis
 Urethra
 Urine
 Ureter
 Renal capsule
 Glomerulus
 nephrons
 Tubules
 Bladder
 Re-absorption
 Loops down
 Filtration
 Dialysis
13.1 What is Excretion?
 The removal of metabolic waste
products & excess substances
◦ CO2 is a waste of Respiration
◦ CO2 is toxic in large amounts
 Excretion ≠ Egestion
◦ The material in feces is not MWP’s; it was never
digested or absorbed.
 Egestion
◦ Getting rid of undigested materials
◦ Ex Cellulose in feces
13.1 Excretory Products
 Carbon Dioxide
◦ Produced by cell Respiration
 Urea
◦ Produced in Liver, removed by kidneys
 Water
◦ In excess, removed by kidneys
Nitrogenous Waste
 Animals produce Nitrogenous waste
 From excess proteins and amino acids
 Cannot stored, broken down into
nitrogen-containing excretory products
 = Urea
Chapter 13.1- EXCRETION IN HUMANS IGCSE BIO
How do you Produce Urea?
 Eat proteins
 Digested into amino acids and absorbed
into your blood
 AA’s travel to the Liver via HPV
 Deamination
◦ Excess AA broken down
◦ Part of AA with energy – stored as glycogen
◦ The part with N will be excreted as Urea
Chapter 13.1- EXCRETION IN HUMANS IGCSE BIO
Chapter 13.1- EXCRETION IN HUMANS IGCSE BIO
Quick Review
1. You eat a protein and break it down into
AA’s. Where do the AA’s go next?
2. What happens to extra AA’s in the Liver?
3. Where does the urea go next?
Answer
1. You eat a protein and break it down into
AA’s. Where do the AA’s go next?
To the Liver (thru the HPV)
2. What happens to extra AA’s in the Liver?
They get deaminated and made into urea
3. Where does the urea go next?
To the kidneys, then out of the body thru the
ureters  bladder  urethra.
Chapter 13.1- EXCRETION IN HUMANS IGCSE BIO
How do you Excrete Urea?
 Protein  AA  Urea
 Urea goes back into the blood - travels to
the kidneys.
 Kidneys take urea out of the blood and mix
it with water to make urine.
 The urine flows from the:
kidneys  2 ureters  bladder.
 Exit thru urethra.
URINE FORMATION
 Filtered as blood passes through kidneys
 Filters
◦ most urea, water, salt, glucose
 Reabsorbs
◦ All glucose, some salts, some water
 Final liquid product – urine
The Human Excretory
system
URINE FORMATION
 Filtered as blood passes through kidneys
 Filters
◦ most urea, water, salt, glucose
 Reabsorbs
◦ All glucose, some salts, some water
 Final liquid product – urine
Chapter 13.1- EXCRETION IN HUMANS IGCSE BIO
Kidney Tubules
 Tiny units of tubules called nephrons
◦ Urea is filtered out of the blood
◦ Begins in the cortex
◦ Ends in the pelvis
◦ Cortex  Medulla  Cortex  Medulla  Pelvis
 Network of blood capillaries around the
nephrons
◦ For reabsorption
Chapter 13.1- EXCRETION IN HUMANS IGCSE BIO
FILTRATION
◦ Glomerulus
 Tangle of blood capillaries
 Blood vessels bring blood here to be filtered
 Towards = wide / Away = narrow
 Builds high pressure
◦ Renal capsule
◦ Water and dissolved substances squeezed out
of blood into renal capsule
◦ Shaped like a cup
◦ Thousands in the cortex
Chapter 13.1- EXCRETION IN HUMANS IGCSE BIO
REABSORPTION
 Useful substances reabsorbed back to the
blood
 Remaining fluid(urine) is excreted
 Kidneys – very efficient
◦ 99% of water reabsorbed
 Kidneys filter 170 L of water per day
 Urine production in adults: 1-2 L per day
Chapter 13.1- EXCRETION IN HUMANS IGCSE BIO
Bladder
 Urine from all tubules flow into ureters
 Ureters take it to bladder
 Stores urine temporarily
 Urethra
◦ Male: 18–20 cm long
◦ Female: 4–6 cm long
 Sphincter muscle
◦ at the top of urethra
 Full bladder - opens
Chapter 13.1- EXCRETION IN HUMANS IGCSE BIO
Chapter 13.1- EXCRETION IN HUMANS IGCSE BIO
Kidney Dialysis
 Dialysis unit
 Used for kidney
failure
 Blood flows through
machine and back
into body
 Treatment – 2 or 3x
a week
Kidney Transplant
 Transplants successful
as long as the blood
type matches
 Rejection
◦ WBCs attack donor organ
 Immunosuppressant
◦ Decrease chances of
rejection
Chapter 13.1- EXCRETION IN HUMANS IGCSE BIO

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Chapter 13.1- EXCRETION IN HUMANS IGCSE BIO

  • 3. Have you ever had bird dropping land on you?  Reptiles and birds  Less water-wasting process for dealing with their bodies' ammonia  Instead of ammonia to urea, they convert it to uric acid  Excreted as a white paste or even a dry, white powder  Through cloacae
  • 4. Terms you should know  Cortex  Medulla  Pelvis  Urethra  Urine  Ureter  Renal capsule  Glomerulus  nephrons  Tubules  Bladder  Re-absorption  Loops down  Filtration  Dialysis
  • 5. 13.1 What is Excretion?  The removal of metabolic waste products & excess substances ◦ CO2 is a waste of Respiration ◦ CO2 is toxic in large amounts  Excretion ≠ Egestion ◦ The material in feces is not MWP’s; it was never digested or absorbed.  Egestion ◦ Getting rid of undigested materials ◦ Ex Cellulose in feces
  • 6. 13.1 Excretory Products  Carbon Dioxide ◦ Produced by cell Respiration  Urea ◦ Produced in Liver, removed by kidneys  Water ◦ In excess, removed by kidneys
  • 7. Nitrogenous Waste  Animals produce Nitrogenous waste  From excess proteins and amino acids  Cannot stored, broken down into nitrogen-containing excretory products  = Urea
  • 9. How do you Produce Urea?  Eat proteins  Digested into amino acids and absorbed into your blood  AA’s travel to the Liver via HPV  Deamination ◦ Excess AA broken down ◦ Part of AA with energy – stored as glycogen ◦ The part with N will be excreted as Urea
  • 12. Quick Review 1. You eat a protein and break it down into AA’s. Where do the AA’s go next? 2. What happens to extra AA’s in the Liver? 3. Where does the urea go next?
  • 13. Answer 1. You eat a protein and break it down into AA’s. Where do the AA’s go next? To the Liver (thru the HPV) 2. What happens to extra AA’s in the Liver? They get deaminated and made into urea 3. Where does the urea go next? To the kidneys, then out of the body thru the ureters  bladder  urethra.
  • 15. How do you Excrete Urea?  Protein  AA  Urea  Urea goes back into the blood - travels to the kidneys.  Kidneys take urea out of the blood and mix it with water to make urine.  The urine flows from the: kidneys  2 ureters  bladder.  Exit thru urethra.
  • 16. URINE FORMATION  Filtered as blood passes through kidneys  Filters ◦ most urea, water, salt, glucose  Reabsorbs ◦ All glucose, some salts, some water  Final liquid product – urine
  • 18. URINE FORMATION  Filtered as blood passes through kidneys  Filters ◦ most urea, water, salt, glucose  Reabsorbs ◦ All glucose, some salts, some water  Final liquid product – urine
  • 20. Kidney Tubules  Tiny units of tubules called nephrons ◦ Urea is filtered out of the blood ◦ Begins in the cortex ◦ Ends in the pelvis ◦ Cortex  Medulla  Cortex  Medulla  Pelvis  Network of blood capillaries around the nephrons ◦ For reabsorption
  • 22. FILTRATION ◦ Glomerulus  Tangle of blood capillaries  Blood vessels bring blood here to be filtered  Towards = wide / Away = narrow  Builds high pressure ◦ Renal capsule ◦ Water and dissolved substances squeezed out of blood into renal capsule ◦ Shaped like a cup ◦ Thousands in the cortex
  • 24. REABSORPTION  Useful substances reabsorbed back to the blood  Remaining fluid(urine) is excreted  Kidneys – very efficient ◦ 99% of water reabsorbed  Kidneys filter 170 L of water per day  Urine production in adults: 1-2 L per day
  • 26. Bladder  Urine from all tubules flow into ureters  Ureters take it to bladder  Stores urine temporarily  Urethra ◦ Male: 18–20 cm long ◦ Female: 4–6 cm long  Sphincter muscle ◦ at the top of urethra  Full bladder - opens
  • 29. Kidney Dialysis  Dialysis unit  Used for kidney failure  Blood flows through machine and back into body  Treatment – 2 or 3x a week Kidney Transplant  Transplants successful as long as the blood type matches  Rejection ◦ WBCs attack donor organ  Immunosuppressant ◦ Decrease chances of rejection