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
Inheritance
Chapter 16

 Chromosome
 Chromatin
 Haploid
 Diploid
 Gene
 Allele
 Mitosis
 Meiosis
 Stem Cell
HW: Define in English and
your Native Language

 Chromosomes – contains long molecule of DNA
 Carry Genetic information
 46 chromosomes in human
 Paired
 Genes
 Code for 1 protein
 Determine your traits
 Over 30, 000 in human body
Chromosomes
Chap 16- Inheritance for High School Class


 Homologous chromosome
 ‘Homologous’
 Similar in structure and size
 We have 22 pairs of
Homologous chromosomes
Cell division


 Haploid cell vs Diploid cell
 Mitosis
 Diploid  Diploid
 Genetically identical
 Repair or produce new cells
 Meiosis
 Diploid  Haploid
 For sex cells
 Produces genetic variation
 Stem cells
 Not yet differentiated
Cell Division

 Alleles – alternative forms of a gene
 Represented by 2 letters
 Homozygous – same alleles (TT, tt) for a gene
 Heterozygous – different alleles (Tt)
Inheritance

 Genotype – genes (letters)
 Phenotype – features/ traits (colors, height)
 Depend on its genotype
 Dominant allele – expressed when present
 Recessive allele – expressed only when Dominant is
absent
 Co-dominance – Both will have an effect on the
phenotype
 Ex: Pink flower or mixed
Inheritance

 Dominant Allele is always written as ‘CAPITAL’
 Recessive Allele is always written as ‘lower case’
 Co-dominant alleles are both expressed
Inheritance
Genotype Phenotype
GG Black Hair
Gg Black Hair
gg Green Hair
Genotype Phenotype
CW
CW
White Flower
CW
CR
Pink Flower
CR
CR
Red Flower

 Alleles in gametes
 Each gamete only 1 kind of chromosome
 Alleles represented by letters (G, g)
 Genetic diagrams – Punnett Square
Inheritance

2 Heterozygous 1 rHomo, 1 hetero

 Blood group A and B are co-dominant
 A + A A blood type
 B + B  B blood type
 A + B  AB blood type
 Both A and B are dominant to O
 A + O  A blood type
 B + O  B blood type
 O + O  O blood type
ABO Blood Groups

 Test cross
 To find out the genotype of an individual with dominant
phenotype for a gene
 Pure breeding: breed homozygous
 Sex determination: XY, XX

 Purpose: To find out the genotype of an individual
with dominant phenotype for a gene
 For e.g.
 T = Black Hair t = Brown Hair
 TT (Homozygous Dominant)
 Black Hair
 Tt (Heterozygous)
 Black Hair
 tt (Homozygous recessive)
 Brown Hair
Test Cross

 How would we know the genotype of a person with
Black Hair?
 Is your genotype TT or Tt?
 Test Cross : Breed it with individual who is known
to be homozygous recessive of that particular gene.
Test Cross

T T
t Tt
Black
Tt
Black
t Tt
Black
Tt
Black
Test Cross
T t
t Tt
Black
tt
Brown
t Tt
Black
tt
Brown
Offspring Result from
Homozygous Dominant
Offspring Result from
Heterozygous

 Pure breeding: Breed homozygous dominant and
recessive
 Offspring are called F1 Generation
T T
t Tt
Black
Tt
Black
t Tt
Black
Tt
Black

 Sex Linkage
 Genes found only on X or Y
chromosome
 Ex. color-blindness (r & g)
Inheritance
Chap 16- Inheritance for High School Class

 What is DNA?
 Made of
 2 strands of Sugar and Phosphate
 4 nitrogen bases: A=T , C=G
 Nucleotide: Sugar + Phosphate + Nitrogen Base
DNA

 Contains code for the sequence of amino acids
 Genetic code:
 In sets of 3= triplets
 For Ex: CCG =glycine
DNA

 Protein synthesis happen in ribosome
 mRNA
 Carries messages from DNA to ribosome
 Transcription – making mRNA
 Copies the base sequence from DNA
 mRNA moves out of nucleus
 Attaches to ribosome
 Translation
 Ribosome links amino acids to make protein
Protein Synthesis

Chap 16- Inheritance for High School Class

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Chap 16- Inheritance for High School Class

  • 2.   Chromosome  Chromatin  Haploid  Diploid  Gene  Allele  Mitosis  Meiosis  Stem Cell HW: Define in English and your Native Language
  • 3.   Chromosomes – contains long molecule of DNA  Carry Genetic information  46 chromosomes in human  Paired  Genes  Code for 1 protein  Determine your traits  Over 30, 000 in human body Chromosomes
  • 5.
  • 6.   Homologous chromosome  ‘Homologous’  Similar in structure and size  We have 22 pairs of Homologous chromosomes Cell division
  • 7.
  • 8.   Haploid cell vs Diploid cell  Mitosis  Diploid  Diploid  Genetically identical  Repair or produce new cells  Meiosis  Diploid  Haploid  For sex cells  Produces genetic variation  Stem cells  Not yet differentiated Cell Division
  • 9.   Alleles – alternative forms of a gene  Represented by 2 letters  Homozygous – same alleles (TT, tt) for a gene  Heterozygous – different alleles (Tt) Inheritance
  • 10.   Genotype – genes (letters)  Phenotype – features/ traits (colors, height)  Depend on its genotype  Dominant allele – expressed when present  Recessive allele – expressed only when Dominant is absent  Co-dominance – Both will have an effect on the phenotype  Ex: Pink flower or mixed Inheritance
  • 11.   Dominant Allele is always written as ‘CAPITAL’  Recessive Allele is always written as ‘lower case’  Co-dominant alleles are both expressed Inheritance Genotype Phenotype GG Black Hair Gg Black Hair gg Green Hair Genotype Phenotype CW CW White Flower CW CR Pink Flower CR CR Red Flower
  • 12.   Alleles in gametes  Each gamete only 1 kind of chromosome  Alleles represented by letters (G, g)  Genetic diagrams – Punnett Square Inheritance
  • 13.  2 Heterozygous 1 rHomo, 1 hetero
  • 14.   Blood group A and B are co-dominant  A + A A blood type  B + B  B blood type  A + B  AB blood type  Both A and B are dominant to O  A + O  A blood type  B + O  B blood type  O + O  O blood type ABO Blood Groups
  • 15.   Test cross  To find out the genotype of an individual with dominant phenotype for a gene  Pure breeding: breed homozygous  Sex determination: XY, XX
  • 16.   Purpose: To find out the genotype of an individual with dominant phenotype for a gene  For e.g.  T = Black Hair t = Brown Hair  TT (Homozygous Dominant)  Black Hair  Tt (Heterozygous)  Black Hair  tt (Homozygous recessive)  Brown Hair Test Cross
  • 17.   How would we know the genotype of a person with Black Hair?  Is your genotype TT or Tt?  Test Cross : Breed it with individual who is known to be homozygous recessive of that particular gene. Test Cross
  • 18.  T T t Tt Black Tt Black t Tt Black Tt Black Test Cross T t t Tt Black tt Brown t Tt Black tt Brown Offspring Result from Homozygous Dominant Offspring Result from Heterozygous
  • 19.   Pure breeding: Breed homozygous dominant and recessive  Offspring are called F1 Generation T T t Tt Black Tt Black t Tt Black Tt Black
  • 20.   Sex Linkage  Genes found only on X or Y chromosome  Ex. color-blindness (r & g) Inheritance
  • 22.   What is DNA?  Made of  2 strands of Sugar and Phosphate  4 nitrogen bases: A=T , C=G  Nucleotide: Sugar + Phosphate + Nitrogen Base DNA
  • 23.   Contains code for the sequence of amino acids  Genetic code:  In sets of 3= triplets  For Ex: CCG =glycine DNA
  • 24.   Protein synthesis happen in ribosome  mRNA  Carries messages from DNA to ribosome  Transcription – making mRNA  Copies the base sequence from DNA  mRNA moves out of nucleus  Attaches to ribosome  Translation  Ribosome links amino acids to make protein Protein Synthesis
  • 25.

Editor's Notes

  • #21: Color blind – pink (for blue) and brown, purple and gray