This document discusses key factors to consider when determining sample size for research. It explains that sample size depends on population size, required confidence level, expected response rate, and other variables. Larger samples are needed when variables are numerous, differences are expected to be small, or subgroups will be analyzed. The standard error of the sample is used to calculate sampling error, which decreases as sample size increases. Both probability and non-probability sampling strategies are outlined. The document provides guidance on planning a sampling strategy that considers research questions, population characteristics, and feasibility of access to samples.