This paper presents an analytical model for the characteristics of a silicon tunnel field-effect transistor (TFET) based on charge plasma (CP), highlighting its potential application in biosensing. The study investigates various electrical parameters and conditions that optimize the performance of the CP-TFET, concluding that specific work functions and device structures significantly enhance its detection capabilities for uncharged molecules in bio-sample solutions. Results indicate improvements in subthreshold slope, ion/off ratios, and overall device performance through strategic manipulation of structural factors.