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Chlamydia Class Presentation
o Possibly the most
            Chlamydia             common STI in the United
                                  States with about 2.8
                                  million men and women
          Chlamydia trachomatis   affected.
                                  o Transmitted through
                                  contact with mucous
                                  membranes found in
                                  eyes, mouth, vagina, rectum
                                  , or urethra.
                                  o Only 25% of men have no
                                  symptoms, rather than the
                                  75% found in females.
                                  o Also known as the:
                                      oClam
                                      oGooey Stuff
                                      oClap Slap
                                      oSilent Epidemic

http://youtu.be/D4Y3QXOZY6E
Rates By Sex, 1990 - 2010
Rates by County
Lighter blue is Audrain and Howard counties, Darker blue is Boone and Cole.
Rates by Age and Sex, 2010
Signs and Symptoms: Women
• Vaginal Discharge
• Burning or painful
  urination
• Abdominal or low back
  pain
• Nausea
• Fever
• Pain with intercourse
• Vaginal bleeding
  between periods.
Signs and Symptoms: Men
          • Burning, frequent, and
            painful urination
          • Penile discharge
          • Swollen and painful
            testicles
          • If rectally: characterized
            by pain, discharge, and
            bleeding.
Complications for Women
                           • Cervicitis:
• Pelvic Inflammatory        inflammation of the
  Disease (PID):             cervix.
  infection of the
  uterus, ovaries and
  fallopian tubes.
• Infertility related to
  upper genital tract
  infection causing
  permanent damage
  to fallopian tubes.
Complications for Men
• Epididymitis: painful
  inflammation of the
  tube system that is part
  of the testicles, which
  can lead to being sterile
  and infertility.
• Urethritis: inflammation
  of the urethra
• Reactive arthritis:
  inflammation of
  joints, urethra, and
  eyes. (Reiters
  Syndrome)
Complications During and After
             Pregnancy
During:
Some evidence suggests that it may
lead to premature delivery




                                                                After:
                                Babies may become infected in the
                               respiratory tract or their eyes during
                                                the birthing process.
Diagnostic Testing:
Based on individual sexual history and lab results.




 • Urinalysis
Antigen Detection Test
                         Diagnostic Testing
                                             Antigen detection
                           methods, including the enzyme-
                           linked immunosorbent assy and
                            the direct fluorescent antibody
                              test are the diagnostic tests of
                          choice for identifying Chlamydial
                               infection, although tissue cell
                            cultures are more sensitive and
                                 specific. Newer nucleic acid
                           probes using poly-merase chain
                             reaction are also commercially
                                                      available.
                                •It is a rapid test designed to
                                   detect the presence of the
                         chlamydia antigen from male and
                                            female swab tests.
Diagnostic Testing
  Pap Smear
Although a pap smear
itself can’t be used to
detect Chlamydia, the
swab taken during the
test is used for the
antigen detection test.
Occasionally some
cellular changes will occur
making the cells reactive
and containing pustules.
These are not conducive
to diagnosing Chlamydia.
Diagnostic Testing
   A sample of cells is collected
  and allowed to grow for 48-72
   hours. A specific stain is used
          to detect for the unique
  appearance of c. trachomatis.
  Cell tissue cultures also allows
     for antimicrobial sensitivity
                           testing.




                                         Cell Tissue Culture
A culture is obtained from through aspiration.
Diagnoses in Women
• Chlamydial infection of the cervix (cervicitis)
  is a sexually transmitted infection
  asymptomatic for 50-70% of women.
• It can be passed through vaginal, anal, or
  oral sex.
• 50% of those that do have an asymptomatic
  infection, not detected by their doctor, will
  develop pelvic inflammatory disease (PID)
   – Chronic pelvic pain, infertility, ectopic
     pregnancies, and other complications of
     pregnancy.
‘Silent Epidemic’
• Chlamydia is known as such because in
  women, only 25% of cases are symptomatic.
• The infection can linger for months or years
  before being discovered.
• Symptoms of Chlamydia are:
  – Unusual vaginal bleeding
  and/or dishcharge
  – Abdominal pain
  – Painful sexual intercourse
  – Fever
  – Painful urination and frequency
  of urination
Diagnoses in Men
• Chlamydia shows symptoms of infectious
  urethritis in about 50% of cases.
   –   Painful or burning sensation when urinating
   –   Unusual discharge from penis
   –   Swollen/tender testicles
   –   Fever
• If left untreated, Chlamydia may spread to
  testicles causing epididymitis and possibly
  sterility in rare cases after 6-8 weeks.
• Chlamydia is a potential cause of prostatitis in
  men, but relevance is difficult to determine
  because of possible contamination with
  urethritis.
Treatment
• Recommended first line of treatment for
  adults and adolescents is drug therapy with
  oral doxycycline for 7 days or oral
  azithromycin in a single dose.
•Persons with chlamydia
should abstain from
sexual intercourse until
after full course of
antibiotics or at least 7
days from single dose.
 •Pregnant women
 would be treated
 with erythromycin.
Re-Infection
• All sex partners should be
  evaluated, tested, treated and retested
  within 3 months of initial infection.
• Women whose sex partners have not
  been appropriately treated are at high
  risk for re-infection.
  – Multiple infections can increase risks of
    serious reproductive health complications.
Treatment Medications
• Recommended Regimens
  – Azithromycin: 1 g po in a single dose.
     • Binds with ribosomal subunit of bacteria and
       inhibits protein synthesis. Broad spectrum
       antibiotics.
                             •Doxycycline: 100 mg po
                             bid 7 days
                                 •Binds with ribosomal
                                 units to inhibit protein
                                 synthesis, by
                                 inactivating protein
                                 enzymes.
Treatment: Medications
• Alternative Regimens
  – Erythromycin Base:500 mg po qid 7 days
     • Interferes with protein synthesis in the bacteria.
  – Erythromycin Ethylsuccinate: 800mg po qid
    7 days
     • Binds with ribosomes and suppresses protein
       synthesis.
  – Levofloxacin: 500mg po qd 7 days
     • Interferes with conversion of DNA
  – Ofloxacin: 300 mg po bid 7 days
     • Interferes with conversion of DNA
Alternative Treatment
           A new option for treating partners of
           patients diagnosed with chlamydia is
             ‘patient delivered partner therapy’.
• It is the clinical practice of
  treating the sex partners by
  providing prescriptions or
  medications to the patient
  to take home to his/her
  partner without the heath
  care provider first
  examining the partner.
Nursing Considerations

                          – Always wear gloves
• Laundry needs to be
  done properly
                        • Clean tables and/or
                          beds and change the
• Wash hands between      paper between each
     patients             exam.
Common Nursing Diagnoses
• Sexual dysfunction    • Ineffective health
  R/T painful sexual      maintenance
  intercourse             R/T multiple sex
  AEB Bleeding during     partners
  intercourse.            AEB sanguineous
                          discharge from the
                          penis/vagina
ORAL ANTIBIOTICS
   Nursing      •Patient needs to know to continue to take
Interventions   medicine as ordered, even if symptoms
                subside
                •A follow up with both partners is
                recommended to ensure that neither
                partner is still infected.

                             PREVENTION
                •Teach patients about the importance of
                monogamous relationships with uninfected
                partners.
                •Use of mechanical barriers:
                    •Condoms
                •Simultaneously treating the partner to
                prevent re-infection
                •Emphasize that it is still possible to spread
                infection even though asymptomatic.
Nursing Interventions
• Advise abstinence from sex until treatment
  has been completed
• Ensure partner is treated at the same time
• Report case to public health department
• Ensure patient begins treatment and will
  have access to prescription follow up
• Teach about all STI’s and symptoms
• Explain treatment regimen and adverse
  effects
• Encourage abstinence, monogamy, and safer
  sex methods
• Stress importance of follow up exam and re-
  testing
Patient Teaching

Cause:
 A bacterium, Chlamydia
Trachomatis




                                                       Spread:
                          Usually during sex, man does not
                                 have to ejaculate to spread
                           infection. Impossible to become
                             infected by touching an object
                                            like a toilet seat.
Patient Teaching
Symptoms: can cause mild to sever symptoms or none at all.

• Women-up to 50% have • Men- common
  no symptoms at         symptoms include:
  all, most common        – Burning or pain with
  include:                  urination
   – Vaginal discharge           – Discharge from the
                                   penis
   – Abnormal vaginal
     bleeding                    – Pain or tenderness of
                                   testes
   – Abdominal pain
                                 – Swelling in scrotum
   – Pain during sex
   – Burning or pain with
     urination
Patient Teaching
TESTING FOR CHLAMYDIA
• Once yearly testing is
  recommended for:
   – All sexually active women
     younger than 25 years old
   – Older women with risk
     factors for acquiring
     Chlamydia
   – All pregnant women
Patient Teaching
                                         Prevention
  Complications                      •    Avoid sexual intercourse
• Pelvic Inflammatory Disease        •    Use latex condoms every
   (PID)                                  time men have sex
• If infection is not treated        •    Discuss testing for STI with
   about 30% of women will                doctor or Nurse
   develop scarring of fallopian     •    See doctor if any symptoms
   tubes, resulting in infertility        occur
                                     •    Do not have sex if you or
                                          your partner has abnormal
Treatment                                 discharge, burning with
• One time antibiotic, PO:                urination, or a genital rash
  azithromycin                            or sore.
Information Resources
1. http://www.thesite.org/sexandrelationships/safers
   ex/sexualhealth/chlamydia
2. http://www.cdc.gov/std/chlamydia/default.htm
3. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH
   0002321/
4. http://www.std-gov.org/stds/chlamydia.htm
5. http://www.webmd.com/sexual-
   conditions/guide/chlamydia
6. http://drugster.info/ail/pathography/757/
7. http://www.cdc.gov/std/ept/
Picture Resources
• http://jamiesideas.wordpress.com/ideas/
• http://www.healthline.com/health-
  blogs/teen-health-411/chlamydia-and-teens-0
• http://www.std-gov.org/stds/chlamydia.htm
• http://www.beautifulcervix.com/cervix-photo-
  galleries/pap-smear/

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Chlamydia Class Presentation

  • 2. o Possibly the most Chlamydia common STI in the United States with about 2.8 million men and women Chlamydia trachomatis affected. o Transmitted through contact with mucous membranes found in eyes, mouth, vagina, rectum , or urethra. o Only 25% of men have no symptoms, rather than the 75% found in females. o Also known as the: oClam oGooey Stuff oClap Slap oSilent Epidemic http://youtu.be/D4Y3QXOZY6E
  • 3. Rates By Sex, 1990 - 2010
  • 4. Rates by County Lighter blue is Audrain and Howard counties, Darker blue is Boone and Cole.
  • 5. Rates by Age and Sex, 2010
  • 6. Signs and Symptoms: Women • Vaginal Discharge • Burning or painful urination • Abdominal or low back pain • Nausea • Fever • Pain with intercourse • Vaginal bleeding between periods.
  • 7. Signs and Symptoms: Men • Burning, frequent, and painful urination • Penile discharge • Swollen and painful testicles • If rectally: characterized by pain, discharge, and bleeding.
  • 8. Complications for Women • Cervicitis: • Pelvic Inflammatory inflammation of the Disease (PID): cervix. infection of the uterus, ovaries and fallopian tubes. • Infertility related to upper genital tract infection causing permanent damage to fallopian tubes.
  • 9. Complications for Men • Epididymitis: painful inflammation of the tube system that is part of the testicles, which can lead to being sterile and infertility. • Urethritis: inflammation of the urethra • Reactive arthritis: inflammation of joints, urethra, and eyes. (Reiters Syndrome)
  • 10. Complications During and After Pregnancy During: Some evidence suggests that it may lead to premature delivery After: Babies may become infected in the respiratory tract or their eyes during the birthing process.
  • 11. Diagnostic Testing: Based on individual sexual history and lab results. • Urinalysis
  • 12. Antigen Detection Test Diagnostic Testing Antigen detection methods, including the enzyme- linked immunosorbent assy and the direct fluorescent antibody test are the diagnostic tests of choice for identifying Chlamydial infection, although tissue cell cultures are more sensitive and specific. Newer nucleic acid probes using poly-merase chain reaction are also commercially available. •It is a rapid test designed to detect the presence of the chlamydia antigen from male and female swab tests.
  • 13. Diagnostic Testing Pap Smear Although a pap smear itself can’t be used to detect Chlamydia, the swab taken during the test is used for the antigen detection test. Occasionally some cellular changes will occur making the cells reactive and containing pustules. These are not conducive to diagnosing Chlamydia.
  • 14. Diagnostic Testing A sample of cells is collected and allowed to grow for 48-72 hours. A specific stain is used to detect for the unique appearance of c. trachomatis. Cell tissue cultures also allows for antimicrobial sensitivity testing. Cell Tissue Culture A culture is obtained from through aspiration.
  • 15. Diagnoses in Women • Chlamydial infection of the cervix (cervicitis) is a sexually transmitted infection asymptomatic for 50-70% of women. • It can be passed through vaginal, anal, or oral sex. • 50% of those that do have an asymptomatic infection, not detected by their doctor, will develop pelvic inflammatory disease (PID) – Chronic pelvic pain, infertility, ectopic pregnancies, and other complications of pregnancy.
  • 16. ‘Silent Epidemic’ • Chlamydia is known as such because in women, only 25% of cases are symptomatic. • The infection can linger for months or years before being discovered. • Symptoms of Chlamydia are: – Unusual vaginal bleeding and/or dishcharge – Abdominal pain – Painful sexual intercourse – Fever – Painful urination and frequency of urination
  • 17. Diagnoses in Men • Chlamydia shows symptoms of infectious urethritis in about 50% of cases. – Painful or burning sensation when urinating – Unusual discharge from penis – Swollen/tender testicles – Fever • If left untreated, Chlamydia may spread to testicles causing epididymitis and possibly sterility in rare cases after 6-8 weeks. • Chlamydia is a potential cause of prostatitis in men, but relevance is difficult to determine because of possible contamination with urethritis.
  • 18. Treatment • Recommended first line of treatment for adults and adolescents is drug therapy with oral doxycycline for 7 days or oral azithromycin in a single dose. •Persons with chlamydia should abstain from sexual intercourse until after full course of antibiotics or at least 7 days from single dose. •Pregnant women would be treated with erythromycin.
  • 19. Re-Infection • All sex partners should be evaluated, tested, treated and retested within 3 months of initial infection. • Women whose sex partners have not been appropriately treated are at high risk for re-infection. – Multiple infections can increase risks of serious reproductive health complications.
  • 20. Treatment Medications • Recommended Regimens – Azithromycin: 1 g po in a single dose. • Binds with ribosomal subunit of bacteria and inhibits protein synthesis. Broad spectrum antibiotics. •Doxycycline: 100 mg po bid 7 days •Binds with ribosomal units to inhibit protein synthesis, by inactivating protein enzymes.
  • 21. Treatment: Medications • Alternative Regimens – Erythromycin Base:500 mg po qid 7 days • Interferes with protein synthesis in the bacteria. – Erythromycin Ethylsuccinate: 800mg po qid 7 days • Binds with ribosomes and suppresses protein synthesis. – Levofloxacin: 500mg po qd 7 days • Interferes with conversion of DNA – Ofloxacin: 300 mg po bid 7 days • Interferes with conversion of DNA
  • 22. Alternative Treatment A new option for treating partners of patients diagnosed with chlamydia is ‘patient delivered partner therapy’. • It is the clinical practice of treating the sex partners by providing prescriptions or medications to the patient to take home to his/her partner without the heath care provider first examining the partner.
  • 23. Nursing Considerations – Always wear gloves • Laundry needs to be done properly • Clean tables and/or beds and change the • Wash hands between paper between each patients exam.
  • 24. Common Nursing Diagnoses • Sexual dysfunction • Ineffective health R/T painful sexual maintenance intercourse R/T multiple sex AEB Bleeding during partners intercourse. AEB sanguineous discharge from the penis/vagina
  • 25. ORAL ANTIBIOTICS Nursing •Patient needs to know to continue to take Interventions medicine as ordered, even if symptoms subside •A follow up with both partners is recommended to ensure that neither partner is still infected. PREVENTION •Teach patients about the importance of monogamous relationships with uninfected partners. •Use of mechanical barriers: •Condoms •Simultaneously treating the partner to prevent re-infection •Emphasize that it is still possible to spread infection even though asymptomatic.
  • 26. Nursing Interventions • Advise abstinence from sex until treatment has been completed • Ensure partner is treated at the same time • Report case to public health department • Ensure patient begins treatment and will have access to prescription follow up • Teach about all STI’s and symptoms • Explain treatment regimen and adverse effects • Encourage abstinence, monogamy, and safer sex methods • Stress importance of follow up exam and re- testing
  • 27. Patient Teaching Cause: A bacterium, Chlamydia Trachomatis Spread: Usually during sex, man does not have to ejaculate to spread infection. Impossible to become infected by touching an object like a toilet seat.
  • 28. Patient Teaching Symptoms: can cause mild to sever symptoms or none at all. • Women-up to 50% have • Men- common no symptoms at symptoms include: all, most common – Burning or pain with include: urination – Vaginal discharge – Discharge from the penis – Abnormal vaginal bleeding – Pain or tenderness of testes – Abdominal pain – Swelling in scrotum – Pain during sex – Burning or pain with urination
  • 29. Patient Teaching TESTING FOR CHLAMYDIA • Once yearly testing is recommended for: – All sexually active women younger than 25 years old – Older women with risk factors for acquiring Chlamydia – All pregnant women
  • 30. Patient Teaching Prevention Complications • Avoid sexual intercourse • Pelvic Inflammatory Disease • Use latex condoms every (PID) time men have sex • If infection is not treated • Discuss testing for STI with about 30% of women will doctor or Nurse develop scarring of fallopian • See doctor if any symptoms tubes, resulting in infertility occur • Do not have sex if you or your partner has abnormal Treatment discharge, burning with • One time antibiotic, PO: urination, or a genital rash azithromycin or sore.
  • 31. Information Resources 1. http://www.thesite.org/sexandrelationships/safers ex/sexualhealth/chlamydia 2. http://www.cdc.gov/std/chlamydia/default.htm 3. http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH 0002321/ 4. http://www.std-gov.org/stds/chlamydia.htm 5. http://www.webmd.com/sexual- conditions/guide/chlamydia 6. http://drugster.info/ail/pathography/757/ 7. http://www.cdc.gov/std/ept/
  • 32. Picture Resources • http://jamiesideas.wordpress.com/ideas/ • http://www.healthline.com/health- blogs/teen-health-411/chlamydia-and-teens-0 • http://www.std-gov.org/stds/chlamydia.htm • http://www.beautifulcervix.com/cervix-photo- galleries/pap-smear/

Editor's Notes

  • #2: http://youtu.be/D4Y3QXOZY6E