This presentation discusses how clusters can be used to increase regional innovation potential and attractiveness. It defines clusters as groups of interconnected companies, specialized suppliers, service providers, and associated institutions in related fields that are present in a particular location. The presentation provides examples of how identifying target clusters based on regional strengths and developing cluster programs with activities like funding R&D projects, business incubators and regional promotion can support innovations, attract and retain companies, and drive economic growth. International case studies from locations like Finland, Cyprus, Botswana, Kazakhstan and Russia are examined to show how cluster development has worked in different contexts.