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CODON OPTIMIZATION
By
HARSHITHA EBBALI
2021502009
I M.Sc Bioinformatics
CONTENTS
# Glimpse on Central dogma
# What are Codons
# What is Codon Optimization
# Why Codon Optimization
CENTRAL DOGMA
codon_optimization
CODONS:
CODONS
• Codons are three nucleotide based in RNA
• It specify amino acid needed for protein
codon_optimization
CODON OPTIMIZATION
• Codon optimization is a process used to improve gene
expression and increase the translational efficiency of a
gene of interest by accommodating codon bias of the host
organism.
• Codon usage biases are found in all eukaryotic and
prokaryotic genome
CGA
CGG Argenine
CGU
CGC
CODON OPTIMIZATION
codon_optimization
codon_optimization
Codon optimization tools:
• Twistbioscience
• Idtdna
• Genscript
• Vectorbuilder
• Genewiz

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codon_optimization