This document compares P, PI, and PID controllers for pH neutralization in a continuous stirred tank reactor (CSTR) system. It describes the pH system and different controller types. Simulations were conducted in MATLAB to analyze the response of each controller tuned using various methods. The PID controller tuned with the Tyreus-Luyben method performed best with minimum error indices and good stability and robustness in attaining the desired pH value without oscillations. The document concludes the PID controller is most suitable for controlling the pH neutralization process.