This document compares the seismic performance of a 9-story reinforced concrete building located on sloping ground with and without base isolation. Six building models are analyzed with slopes of 0, 10, 20, and 30 degrees using ETABS software. Results show that base isolation increases drift but decreases base shear by around 55% as slope increases. Isolated buildings have displacement 2-3 times higher but time period increases 2.65 times. Base isolation at the foundation provides more efficient seismic performance compared to other positions. Lead rubber bearings are suitable for low to medium rise buildings on sloping sites.