This document compares the shaping ability of 10 rotary and reciprocating endodontic systems (F360, F6SkyTaper, HyflexEDM, iRace, Neoniti, O.Shape, P.Next, Reciproc, Revo-S, and WaveOneGold) using size 25 files. 300 teeth were divided into 10 groups and instrumented with one of the systems. Cutting area, preservation of root canal anatomy, and uninstrumented areas were analyzed using AutoCAD. Statistical analysis found significant differences between systems for cutting area and uninstrumented areas, but not for preserving anatomy. Reciproc and Neoniti performed best overall at removing dentin while maintaining original canal shape.