This document outlines a framework for influencing policy change through research. It discusses four key components to consider: the political context, the evidence, links between stakeholders, and the external environment. For each component, it provides questions researchers should consider to understand the situation, actions they can take to influence policy, and recommendations on how to implement those actions, such as building relationships with policymakers, establishing credibility over time, and aligning research with international priorities. The overall goal is to provide guidance to researchers on strategically influencing policy through different approaches based on the issue context.