Contributions of Jean-Claude Bradley to the vision and execution of Open Notebook Science
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Jean-Claude Bradley significantly contributed to open notebook science, advocating for transparency and data sharing in the scientific community. His initiatives, such as UsefulChem, emphasized the importance of making experimental data openly accessible, ultimately benefiting thousands of scientists. He passionately supported high-quality data validation and the collaborative use of technology for teaching and research.
Contributions of Jean-Claude Bradley to the vision and execution of Open Notebook Science
- 1. Contributions of Jean-Claude Bradley to the vision and execution of Open Notebook Science Andrew SID Lang, Oral Roberts University Antony J Williams, ChemConnector
- 2. Why Open?
- 3. Q: Why did you decide to adopt an open approach? A: In thinking about what has meaning for me as a scientist, I realized that the work I was doing wasn’t having the kind of impact that I would like it to have, and it was not benefitting mankind in the way I would have hoped. I concluded that this was partly a consequence of secrecy. However, I couldn’t be open with the project I was then working on, because I was collaborating with someone who didn’t feel the same way as me. My decision to do open science meant cutting ties with my previous collaborators. Having done that in 2005, I started the project UsefulChem. http://www.infotoday.com/it/sep10/Poynder.shtml Interview With Jean-Claude Bradley The Impact of Open Notebook Science by Richard Poynder
- 6. Open Source Science >>
- 7. Open Notebook Science Influenced by: Peter Murray-Rust & Beth Ritter-Guth http://drexel-coas-elearning.blogspot.com/2006/09/open-notebook-science.html
- 8. Open Notebook Science Jean-Claude Bradley Dec 11, 2008 NIST Associate Professor of Chemistry Drexel University
- 9. The current paradigm of doing and sharing science in chemistry 1. Design experiments based on established or potentially new theories. 2. Execute and record experimental outcomes in private notebooks. 3. When a sufficient narrative emerges selective experimental data are combined to publish, with a limited amount of “supplementary supporting data”
- 10. What kind of (chemical) worldview has this approach created? 1. Selective bias towards which experiment are even attempted. 2. Overconfidence in our understanding since deviant or ambiguous results are rarely reported.
- 11. Open and Closed Science Traditional Lab Notebook (unpublished) Traditional Journal Article Open Access Journal Article Open Notebook Science (full transparency) CLOSED OPEN Traditional Paper Textbook F2F lectures Lectures Notes public Assigned problems public Archived Lectures Public and free online textbooks RESEARCH TEACHING
- 12. Motivation: Faster Science, Better Science
- 13. Where is Science headed? WE ARE HERE
- 14. There are NO FACTS, only measurements embedded within assumptions Open Notebook Science maintains the integrity of data provenance by making assumptions explicit
- 15. TRUST PROOF
- 16. Open Notebook Science Challenge Co-conceived with Cameron Neylon https://www.flickr.com/photos/24801682@N08/2824469941/ http://usefulchem.blogspot.com/2008/09/open-notebook-science-challenge.html
- 17. 359 ONS Experiments 4,640 CC0 non-aqueous solubilities 28,645 CC0 melting points http://figshare.com/articles/Jean_Claude_Bradley_Open_Melting_Point_Datset/1031637
- 18. Where is Science headed? WE ARE HERE
- 19. Open Notebook Science >>
- 20. • He gave soooooo much early feedback on how ChemSpider could serve the community – the first advisory group member • For ChemSpider he contributed his students to perform crowdsourced curation and annotation • JC tapped into ChemSpider a lot for validated data and integration to his ONS wikis • He deposited data onto ChemSpider so we could link directly • His Open Notebook Science data was made available to over 10,000 scientists a day via ChemSpider JC took.. and he GAVE AWAY
- 21. Feeding ONS MP Data into ChemSpider ONS data deposited into ChemSpider and linked out to ONS pages
- 23. Feeding ONS Sol. Data into ChemSpider ONS Solubility Challenge
- 24. Linking to ONS Data from ChemSpider
- 25. Building Teaching Tools • JC loved to use technology to TEACH. He used freely available tools to do so – including ChemSpider services
- 28. Collaborations in Openness • JC believed in HIGH-QUALITY data • He invested himself, and his students, in validating, checking and re-measuring data • He demanded openness of data, free of restrictions and constraints • Do his efforts make a difference???
- 30. JC and Drug Discovery • JC cared passionately about neglected disease research • Many of our conversations were around better data-sharing for the various groups • We continue in our mission to help…
- 31. Journal of Cheminformatics Issue Seven articles already published and three more in the pipeline. Submit yours before the end of the year!