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COPD with
Respiratory Failure
Patient Background

 Daishi Hayato
   Age 65
   Male
   Asian American
   Retired
   Wife and 4 adult children
   Father had lung cancer

 Primary Diagnosis:
  Acute respiratory distress, COPD, peripheral vascular disease
    with intermittent claudication
Etiology

 Acute Respiratory Distress (ARDS)
   Occurs when fluid builds up in the alveoli in the lungs
   More fluid in the lungs means less oxygen can reach your
    bloodstream, depriving organs of the oxygen they need to
    function
   Primary symptom: Severe shortness of breath
Etiology

 COPD – Chronic Obstructive Pulmonary Disease
   A progressive disease in which airflow is limited or restricted
   Most times associated with emphysema (destruction of
    alveoli/lungs over time), bronchitis (inflammation of the
    lining of the bronchial tubes), or in rare cases, a genetic
    protein deficiency
   Primary risk factor: Smoking
      Mr. Hayato was diagnosed with emphysema more than
        10 years ago and has a long-standing history of COPD
        secondary to chronic tobacco use of 2 packs per
        day for 50 years
Etiology
Etiology

 Peripheral vascular disease with intermittent claudication
   Peripheral vascular disease occurs when the arteries in the
     extremities become clogged with a fatty substance called
     plaque
   This plaque build up causes atherosclerosis in the arteries,
     obstructing blood flow
   The blocked arteries cause
  claudication or “crampy
     leg” when exercising, with pain
     that comes and goes
Nutrition History

 Appetite: Fair but         BMI: 21.7 kg/m2
  decreasing
                             %UBW: 90%
 Largest meal: Breakfast
                             IBW: 126 lbs
 Highest Weight: 135 lbs
                             %IBW: 97%
 Current Weight: 122 lbs
                             Unintended Weight Loss
 Height: 5’4”
                             Estimated REE needs:
 No previous nutrition       1500 – 1600 kcals
  therapy                      80 - 83 grams protein
At the Hospital

 Chest tube inserted into left thorax with drainage under
  suction

 Endotracheal intubation

 Placed on ventilation
   15 breaths/min with an FiO2 of 100%
   Positive end-expiratory pressure of 6
   Tidal volume of 700 mL

 Daily chest radiographs (X-ray) and ABGs each A.M.
Treatment Plan

 ABG, pulse oximetry, CBC, chemistry panel, UA
  (urinalysis)

 Chest X-ray, ECG, Proventil

 IVF D5 ½ NS at TKO

 Spirogram post nebulizer tx

 NPO

 Increased calorie needs (10-15%)
Tube Feedings

 Initiated on Day 2 of admission
   Isosource @ 25 cc/hr continuously over 24 hours
      Receiving 720 calories and 25.8 grams of protein per day

 High gastric residuals led to discontinued use of enteral
  feeding and initiation of peripheral parenteral nutrition
  (PPN)

 PPN @ 100 cc/hr
   ProcalAmine – 3% glycerin, 3% amino acids
      Receiving 312 calories and 69.6 grams of protein per day
   Regular IV at D5 ½ NS at TKO was discontinued
Tube Feedings

 Day 4: Enteral feeds restarted @ 25 cc/hr, increased to 50
  cc/hr after 12 hours
   ProcalAmine also continued @ 100 cc/hr
   Total Energy Intake: 1,712 calories – excessive

 Respiratory status became worse on Day 5; ProcalAmine
  was discontinued

 Enteral feedings continued until Day 8

 Patient weaned from ventilator Day 8

 Discharged on Day 11
Lab Values:
     Arterial Blood Gases (ABGs)

70
        65                  66
60                60
        56                  57
50                50
                                   pH
40                                 pCO2
        35                  36
30                29               CO2
                                   pO2
20
                                   HCO3
10
        7.2       7.36      7.22
0
     Day 1     Day 3     Day 5
Medical Nutrition Therapy:
       Nutrition Diagnosis


Excessive intake from enteral/parenteral
nutrition related to excessive energy intake
as evidenced by elevated CO2 levels and an
increased RQ
Medical Nutrition Therapy:
              Intervention

 Initiate EN or PN (ND-2.1)

 Modify rate, concentration, composition, or schedule
  (ND-2.2)

 Discontinue EN or PN (ND-2.3)

 Priority modification (E-1.2)

 Goal setting (C-2.2)

 Social support (C-2.5)
Medical Nutrition Therapy:
           Monitor & Evaluation

 Monitor enteral feeding tolerance (residuals) &
  peripheral parenteral nutrition
 Monitor lab values
   Arterial blood gases (ABGs)
   pH
   Blood counts
   RQ

 Monitor weight gain/loss
Medical Nutrition Therapy:
D/C Treatment for Mr. Hayato

 Prevent further weight loss by eating sufficient calories

 Consume a diet rich in antioxidants  fruits, vegetables, and
   fish helps lower incidence of COPD
    Decrease consumption of red meats, refined grains, desserts and
      french fries

 Increased consumption of vitamins C, A, and E and beta-
   carotene to help cope with oxidative damage undergone during
   exacerbation which depletes concentrations of these vitamins

 Monitor phosphate levels for adequacy; crucial for pulmonary
   function because it is essential for synthesis of ATP
Medical Nutrition Therapy:
D/C Treatment for Mr. Hayato

 Assess calcium and vitamin D intake and ensure adequacy to
   help prevent osteoporosis

 Advise patient to consume good sources of protein and
   calories, as well as sources that are nutrient dense

 Rest before meals to avoid fatigue

 Eat smaller, more frequent meals to alleviate feelings of fullness
   and bloating

 Advise exercise, as capable
   Strength/resistance training may help improve skeletal muscle
      function; skeletal muscle dysfunction is often an indicator of
      COPD in its advanced stages
Prognosis


 There is no cure for COPD

 Ways to Improve Overall Quality of Life:
   Smoking Cessation
   Dietary changes
   Taking medications as directed
   Routine medical care and as needed
Question #1




Why are high gastric residuals in tube-fed
           patients dangerous?
Question #2



What primary macronutrient makes it more
      difficult to wean a patient from a
                   ventilator?


                 Why?
Question #3



What two factors indicated that Mr. Hayato
  was receiving excess nutrition from his
       parenteral and enteral feeds?
References

http://www.mayoclinic.com/health/ards/DS00944

http://www.emphysemafoundation.org/pulmonary-disease/57-copd.html

http://www.rxlist.com/procalamine-side-effects-drug-center.htm

http://www.todaysdietitian.com/newarchives/060210p8.shtml

http://www.in.gov/fssa/files/aspiration_prevention_8.pdf.

Medeiros, D., Wildman, R. (2009). “Advanced human nutrition.” Sudbury, MA: Joans and Bartlett Learning, LLC.

Nelms, M., Sucher, K. (2011). “Nutrition therapy and pathophysiology.” Belmont, CA: Wadsworth Cengage Learning.

http://www.umm.edu/patiented/articlesintermittent_claudication_other_symptoms_of_peripheral_artery_disease_000102

http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=66097

http://www.drugs.com/pro/procalamine.html

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COPD with Respiratory Failure

  • 2. Patient Background  Daishi Hayato  Age 65  Male  Asian American  Retired  Wife and 4 adult children  Father had lung cancer  Primary Diagnosis: Acute respiratory distress, COPD, peripheral vascular disease with intermittent claudication
  • 3. Etiology  Acute Respiratory Distress (ARDS)  Occurs when fluid builds up in the alveoli in the lungs  More fluid in the lungs means less oxygen can reach your bloodstream, depriving organs of the oxygen they need to function  Primary symptom: Severe shortness of breath
  • 4. Etiology  COPD – Chronic Obstructive Pulmonary Disease  A progressive disease in which airflow is limited or restricted  Most times associated with emphysema (destruction of alveoli/lungs over time), bronchitis (inflammation of the lining of the bronchial tubes), or in rare cases, a genetic protein deficiency  Primary risk factor: Smoking  Mr. Hayato was diagnosed with emphysema more than 10 years ago and has a long-standing history of COPD secondary to chronic tobacco use of 2 packs per day for 50 years
  • 6. Etiology  Peripheral vascular disease with intermittent claudication  Peripheral vascular disease occurs when the arteries in the extremities become clogged with a fatty substance called plaque  This plaque build up causes atherosclerosis in the arteries, obstructing blood flow  The blocked arteries cause claudication or “crampy leg” when exercising, with pain that comes and goes
  • 7. Nutrition History  Appetite: Fair but  BMI: 21.7 kg/m2 decreasing  %UBW: 90%  Largest meal: Breakfast  IBW: 126 lbs  Highest Weight: 135 lbs  %IBW: 97%  Current Weight: 122 lbs  Unintended Weight Loss  Height: 5’4”  Estimated REE needs:  No previous nutrition 1500 – 1600 kcals therapy  80 - 83 grams protein
  • 8. At the Hospital  Chest tube inserted into left thorax with drainage under suction  Endotracheal intubation  Placed on ventilation  15 breaths/min with an FiO2 of 100%  Positive end-expiratory pressure of 6  Tidal volume of 700 mL  Daily chest radiographs (X-ray) and ABGs each A.M.
  • 9. Treatment Plan  ABG, pulse oximetry, CBC, chemistry panel, UA (urinalysis)  Chest X-ray, ECG, Proventil  IVF D5 ½ NS at TKO  Spirogram post nebulizer tx  NPO  Increased calorie needs (10-15%)
  • 10. Tube Feedings  Initiated on Day 2 of admission  Isosource @ 25 cc/hr continuously over 24 hours  Receiving 720 calories and 25.8 grams of protein per day  High gastric residuals led to discontinued use of enteral feeding and initiation of peripheral parenteral nutrition (PPN)  PPN @ 100 cc/hr  ProcalAmine – 3% glycerin, 3% amino acids  Receiving 312 calories and 69.6 grams of protein per day  Regular IV at D5 ½ NS at TKO was discontinued
  • 11. Tube Feedings  Day 4: Enteral feeds restarted @ 25 cc/hr, increased to 50 cc/hr after 12 hours  ProcalAmine also continued @ 100 cc/hr  Total Energy Intake: 1,712 calories – excessive  Respiratory status became worse on Day 5; ProcalAmine was discontinued  Enteral feedings continued until Day 8  Patient weaned from ventilator Day 8  Discharged on Day 11
  • 12. Lab Values: Arterial Blood Gases (ABGs) 70 65 66 60 60 56 57 50 50 pH 40 pCO2 35 36 30 29 CO2 pO2 20 HCO3 10 7.2 7.36 7.22 0 Day 1 Day 3 Day 5
  • 13. Medical Nutrition Therapy: Nutrition Diagnosis Excessive intake from enteral/parenteral nutrition related to excessive energy intake as evidenced by elevated CO2 levels and an increased RQ
  • 14. Medical Nutrition Therapy: Intervention  Initiate EN or PN (ND-2.1)  Modify rate, concentration, composition, or schedule (ND-2.2)  Discontinue EN or PN (ND-2.3)  Priority modification (E-1.2)  Goal setting (C-2.2)  Social support (C-2.5)
  • 15. Medical Nutrition Therapy: Monitor & Evaluation  Monitor enteral feeding tolerance (residuals) & peripheral parenteral nutrition  Monitor lab values  Arterial blood gases (ABGs)  pH  Blood counts  RQ  Monitor weight gain/loss
  • 16. Medical Nutrition Therapy: D/C Treatment for Mr. Hayato  Prevent further weight loss by eating sufficient calories  Consume a diet rich in antioxidants  fruits, vegetables, and fish helps lower incidence of COPD  Decrease consumption of red meats, refined grains, desserts and french fries  Increased consumption of vitamins C, A, and E and beta- carotene to help cope with oxidative damage undergone during exacerbation which depletes concentrations of these vitamins  Monitor phosphate levels for adequacy; crucial for pulmonary function because it is essential for synthesis of ATP
  • 17. Medical Nutrition Therapy: D/C Treatment for Mr. Hayato  Assess calcium and vitamin D intake and ensure adequacy to help prevent osteoporosis  Advise patient to consume good sources of protein and calories, as well as sources that are nutrient dense  Rest before meals to avoid fatigue  Eat smaller, more frequent meals to alleviate feelings of fullness and bloating  Advise exercise, as capable  Strength/resistance training may help improve skeletal muscle function; skeletal muscle dysfunction is often an indicator of COPD in its advanced stages
  • 18. Prognosis  There is no cure for COPD  Ways to Improve Overall Quality of Life:  Smoking Cessation  Dietary changes  Taking medications as directed  Routine medical care and as needed
  • 19. Question #1 Why are high gastric residuals in tube-fed patients dangerous?
  • 20. Question #2 What primary macronutrient makes it more difficult to wean a patient from a ventilator? Why?
  • 21. Question #3 What two factors indicated that Mr. Hayato was receiving excess nutrition from his parenteral and enteral feeds?
  • 22. References http://www.mayoclinic.com/health/ards/DS00944 http://www.emphysemafoundation.org/pulmonary-disease/57-copd.html http://www.rxlist.com/procalamine-side-effects-drug-center.htm http://www.todaysdietitian.com/newarchives/060210p8.shtml http://www.in.gov/fssa/files/aspiration_prevention_8.pdf. Medeiros, D., Wildman, R. (2009). “Advanced human nutrition.” Sudbury, MA: Joans and Bartlett Learning, LLC. Nelms, M., Sucher, K. (2011). “Nutrition therapy and pathophysiology.” Belmont, CA: Wadsworth Cengage Learning. http://www.umm.edu/patiented/articlesintermittent_claudication_other_symptoms_of_peripheral_artery_disease_000102 http://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?id=66097 http://www.drugs.com/pro/procalamine.html