This document provides instructions for mining Twitter user profile data using Python. It discusses setting up API keys, installing necessary Python libraries like Twython and SQLite, creating a list of Twitter screennames, setting up a SQLite database to store Twitter data, and analyzing the Python code to extract and store Twitter user profile information from the Twitter API based on the screenname list. The code extracts profile fields like screenname, followers count, location, bio and stores it in the SQLite database. Rate limits from the Twitter API require running the code multiple times to get all user profile data.