Chapter 6 of 'Database System Concepts, 6th Edition' covers formal relational query languages including relational algebra and calculus, detailing operations such as selection, projection, union, and natural joins. It introduces both the procedural and non-procedural query languages, emphasizing the foundational principles for manipulating and querying relational databases. Additionally, it addresses null values, aggregate functions, and modifications of database content, elucidating the use of extended operations and the differences between relational algebra and SQL.