This document discusses responsibilities to Indigenous peoples, knowledge, and heritage in research and ethics. It notes that Indigenous peoples represent significant cultural diversity globally and are closely connected to biodiversity. Indigenous knowledge is intrinsically tied to language, customs, traditions, and ceremonies, and contains localized meaning. However, colonial research practices have marginalized and exploited Indigenous communities by privileging outsider interpretations and solutions. The document calls for transforming research through respectful Indigenous frameworks and methodologies, recognition of community oversight and benefits, and conceptual development around Indigenous intellectual property rights.