To create a digipak design in Photoshop and InDesign, the document begins by finding the dimensions of a real digipak and disk. It then details steps to create the background design which includes adding noise, blurring, and adjusting levels. Additional steps describe creating a barcode by adding noise and stretching pixels, as well as creating planets by adding textures, glows, and shadows. The document concludes by describing image manipulation techniques like removing backgrounds and adjusting levels to prepare photos for inclusion in the digipak design.