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Dr Mohammed Mahdy,
MD
To learn together
FIRST
One flower can give an odour enough than a bouquet
But can’t give the colorful collection
SECOND
Our aim and objectives
EEG basic to practice 2
EEG basic to practice 2
BRAIN WAVES
EEG Waves
• ‫د‬‫ايما‬‫ت‬‫أتى‬‫ا‬‫لرياح‬‫ب‬‫ياتا‬
• Delta waves – 1 – 3.5 Hz.
• Theta wave -- 4 – 7.5 Hz.
• Alpha wave -- 8 – 13 Hz.
• Beta wave -- >13 Hz. (14 – 30 Hz.)
»D T A B
One second
Alpha Rhythm
‫أ‬‫المخ‬ ‫فى‬ ‫حاجة‬ ‫خر‬-‫ا‬‫صحى‬-‫ا‬‫تتأكد‬ ‫عنيك‬ ‫قفل‬–‫ا‬‫مهم‬ ‫لفرق‬
• The starting point of analysing awake EEG
• 8-13 Hz activity occurring during wakefulness
• 20-60 mV, max over posterior head regions, Waxing & waning
• Present when eyes closed; blocked by eye opening or alerting
the patient
• 8 Hz is reached by 3 years of age and progressively increases
in a stepwise fashion until 9-12 Hz is reached by adolescence
• Very stable in an individual, rarely varying by more than 0.5 Hz.
• With drowsiness, alpha activity may decrease by 1-2 Hz
• A difference of greater than 1 Hz between the two hemispheres
is significant.( Ear referential montage)
• 10% of adult have little or no alpha
EEG basic to practice 2
EEG basic to practice 2
Alpha block
NB
• Unilateral failure of the alpha rhythm to attenuate
reflects an ipsilateral abnormality
(Bancaud’s phenomenon).
• Normally, alpha frequencies may transiently increase immediately
after eye closure
(alpha squeak).
• Alpha variants include forms that are one-half
(slow alpha)
• or two times the frequency with similar distribution and reactivity.
(fast alpha)
• Alertness results in the presence of alpha, and drowsiness does
not.
Paradoxical alpha
Mu Rhythm
Arciform, apiculate negative and rounded positive phase (9-11) Hz.
• - Intermingled with 20 Hz beta. C3,4 & Cz location.
• - may be seen only on one side, and may be quite
asymmetrical and asynchronous, despite the notable absence of
an underlying structural lesion.
• - Normal if other central rhythms symmetrical.
• - Eyes open has no effects.
• block with contralateral movement of an extremity.
• - High voltage over skull defect – breach rhythm.
• - Apiculate phase may resembles spikes.
EEG basic to practice 2
EEG basic to practice 2
EEG basic to practice 2
Beta wave
• Faster than alpha, present in the anterior head area.
• Is a normal finding in the adult awake EEG and can sometimes be
better seen when patient's eyes open.
• Enhanced by drowsiness and some medication especially
barbiturates.14 hz and above; 15-25 Hz most common.
• - - Location: frontal – common;
• central common mixed with Mu.
• Posterior – fast alpha variant.
• Diffuse – when abundant = medication effect
• - Usually < 20 mV; occasionally 20-30 mV.
• - Amplitude and distribution increases by: drowsiness, light sleep,
REM, skull defect, medication especially benzodiazepines, barbiturates,
chloral hydrate.
• - Diffuse theta may accompany medication-induced excess beta.
EEG basic to practice 2
Theta Rhythm
• – Low voltage 4-7 hz diffuse theta a common component of normal
recordings.
• - May be seen at the onset of sleep, not a predominant
rhythm in the normal alert adult EEG.
• - More common in children and young adults than older
adults.
• The appearance of frontal theta can be facilitated by emotions,
focused concentration, and during mental tasks.
• Theta activity is normally enhanced by hyperventilation,
drowsiness, and sleep.
• Intermittent 4- to 5-Hz activity bitemporally, or even with a
lateralized predominance (usually left > right), may occur in
about one-third of the asymptomatic elderly and is not abnormal.
Lambda waves
• O1,2 pricipally. Involve P3,4 & T5,6.
• Bilateral synchronous; diphasic or triphasic.
• Largest wave electropositive lasting 100-
200msec.
• Evoked by scanning well-illuminated,
patterned visual field.
• Present in 50% of normal EEGs.
• Blocked by white paper shuttle
EEG basic to practice 2
DELTA waves
• Less than 4 hz.
• - Not a normal findings in the awake adult EEG.
• - Normally found in the deeper stages of sleep.
• - Hyperventilation Sequencies: Increase in diffuse
theta. Rhythmic delta in bursts. Continuous rhythmic
delta.
• - Effect maximally anterior in most adolescents,
adults maximum amplitude of delta bursts may shift
from side-to-side.
• - Multiples frequencies may create apiculate wave
forms effect greatly in youth with maximum effort and
low serum glucose.
• - Effects subsides in 60-90secs. After HV.
• - Post HV period may contain newly appearing
focal delta or theta as abnormalities.
EEG basic to practice 2
EEG basic to practice 2
EEG basic to practice 2
EEG basic to practice 2
EEG basic to practice 2
EEG basic to practice 2
Stages of sleep EEG pattern Somatic or Behavioral
changes
Alert Alpha activity on eye
closed
Desynchronization on
eye opening
Respond to verbal
commands
I (Drowsiness) Alpha dropout and
slowing & appearance
of vertex waves &
theta.POSTS
Reduced HR & RR
II (Light sleep) Sleep spindles,
vertex sharp waves &
K-complexes, POSTS
Reduced HR & RR
III ( Deep Sleep) Much slow theta-
delta background
K-complexes
No spindles
Reduced HR & RR
IV (very deep
sleep)
Synchronous delta
waves, some K-
complexes
Reduced HR & RR
REM sleep
(paradoxical sleep)
Desynchronization
with faster
frequencies
Mixed frequencies
HR, BP & RR irregular
Marked hypotonia
Rapid eye movement 50
– 60 /min.
Dreaming threshold of
arousal
EEG basic to practice 2
EEG basic to practice 2
Wave variants with sleep
• Vertex (V) Waves
• – Bilaterally synchronous.
• - Maximum amplitude at vertex (Cz) extend to Fz, Pz,
F3,4; C3,4; P3,4.
• - May appear in sequencies; shifting asymmetries occur;
• - .
• - May be preceded and/or followed by smaller waves of
opposite polarity.
• - Highest amplitude and sharpest in youth; become more
blunt with age.
• - Appear principally in light sleep but also in awakefulness,
drowsiness, and at onset of focal pathology.
Post Occipital Sharp
Transients of Sleep (POSTs)
• Sharp-contoured, mornophasic, surface-positive
transients
• Ocurring singly or in trains of 4-5 Hz over the occipital
head regions
• May have a similar appearance to the lambda waves
during the awake record but are of higher voltage and
longer duration
• Usually bilaterally synchronous but may be
asymmetric over the two sides
• Predominantly seen during drowsiness and light
sleep
POSTs
• Spindles –
• Rhythmic or arciform waves.
• - In 2-3 sec bursts, waxing and waning giving spindle
shape.
• - Bilaterally synchronous and symmetrical or
asynchronous with symmetry of total spindle quantity.
• - 13-14 Hz Cz, C3,4 with frontal spread in light stage 2
sleep.
• - 10-12 Hz Fz, F3,4 in deeper stage 2 and stage 3 sleep.
Sleep Spindles
• K Complexes –
• Diphasic waves (Initial brief wave; subsequent slow
wave).
• - + Spindles superimposed on slowed wave stage
2 sleep
EEG basic to practice 2
EEG basic to practice 2
EEG basic to practice 2
Stages of sleep EEG pattern Somatic or Behavioral
changes
Alert Alpha activity on
eye closed
Desynchronization on
eye opening
Respond to verbal
commands
I (Drowsiness) Alpha dropout and
slowing & appearance
of vertex waves &
theta.POSTS
Reduced HR & RR
II (Light sleep) Sleep spindles,
vertex sharp waves &
K-complexes, POSTS
Reduced HR & RR
III ( Deep Sleep) Much slow theta-
delta background
K-complexes
No spindles
Reduced HR & RR
IV (very deep
sleep)
Synchronous delta
waves, some K-
complexes
Reduced HR & RR
REM sleep
(paradoxical sleep)
Desynchronization
with faster
frequencies
Mixed frequencies
HR, BP & RR irregular
Marked hypotonia
Rapid eye movement 50
– 60 /min.
Dreaming threshold of
arousal
EEG basic to practice 2
EEG basic to practice 2
Wave variants with sleep
• Vertex (V) Waves
• – Bilaterally synchronous.
• - Maximum amplitude at vertex (Cz) extend to Fz, Pz,
F3,4; C3,4; P3,4.
• - May appear in sequencies; shifting asymmetries occur;
• - .
• - May be preceded and/or followed by smaller waves of
opposite polarity.
• - Highest amplitude and sharpest in youth; become more
blunt with age.
• - Appear principally in light sleep but also in awakefulness,
drowsiness, and at onset of focal pathology.
Post Occipital Sharp
Transients of Sleep (POSTs)
• Sharp-contoured, mornophasic, surface-positive
transients
• Ocurring singly or in trains of 4-5 Hz over the occipital
head regions
• May have a similar appearance to the lambda waves
during the awake record but are of higher voltage and
longer duration
• Usually bilaterally synchronous but may be
asymmetric over the two sides
• Predominantly seen during drowsiness and light
sleep
POSTs
• Spindles –
• Rhythmic or arciform waves.
• - In 2-3 sec bursts, waxing and waning giving spindle
shape.
• - Bilaterally synchronous and symmetrical or
asynchronous with symmetry of total spindle quantity.
• - 13-14 Hz Cz, C3,4 with frontal spread in light stage 2
sleep.
• - 10-12 Hz Fz, F3,4 in deeper stage 2 and stage 3 sleep.
Sleep Spindles
• K Complexes –
• Diphasic waves (Initial brief wave; subsequent slow
wave).
• - + Spindles superimposed on slowed wave stage
2 sleep
EEG basic to practice 2
EEG basic to practice 2
EEG basic to practice 2
EEG basic to practice 2
Factor influencing EEG
• Age
– Infancy – theta, delta wave
– Child – alpha formation.
– Adult – all four waves.
• Level of consciousness (sleep)
• Sedation
• Hypocapnia (hyperventilation) slow & high amplitude
waves.
• Hypoglycemia
• Hypothermia
• Low glucocorticoids
Slow waves
PROVOCATIVE TECHNIQUES
Hyperventillation
• The usefulness of HV depends on vasoconstriction secondary to
resultant decreased CO2 concentration, thus inducing relative cerebral
ischemia and decreased glucose utilization.
• A complain of lightheadedness or tingling in the extremities.
• Even tetany secondary to hypocalcemia may occur with particularly
vigorous HV.
• The procedure is most effective in the young; in the elderly it has little
effect.
• The standard response is moderate to high-voltage, often rhythmic,
delta and theta slowing with bifrontal preponderance
• As a rule, HV is carried out for 3 minutes with vigorous exhalation at an
increased but not particularly rapid rate.
• Rapid HV moves little air and has correspondingly little effect.
• After the conclusion of HV the record should return to baseline levels in
about 1 minute
• it is not performed in patients with pulmonary and cardiac disease.
EEG basic to practice 2
Photic stimulation
• easily carried out with strobe units that flash for 5–
10 seconds at frequencies typically between 1 and
35 Hz.
• If the response to the flash train is 1 : 1 it is termed
the fundamental.
• It is not unusual to see harmonic (twice the flash
frequency) and/or subharmonic (half the flash
frequency) responses.
• If photic driving is absent on one side, it may
support a diagnosis of unilateral structural disease
involving the occipital region (e.g., infarction in
posterior cerebral artery territory).
EEG basic to practice 2
EEG basic to practice 2
Sleep deprived
• Sleep deprivation is a powerful activator of epileptiform
activity.
• It is sometimes suggested that the subject stay up all
night before his or her appointment the next morning,
but a brief period of sleep may be permitted.
• No caffeinated beverages are permitted,
• Carry out HV early in the recording
• One can expect an increase in or de novo appearance
of focal epileptiform activity in about 30% of patients
with epilepsy
BLAH
BLAH
BLAH
BLAH
B
BLAH
BLAH
1. Frequency of brain
waves in sequence of
DTAB, same to age
progression
2. Sleep changes very
important, it is a source of
confusion with pathology,
and a source of abused
EEG and AED.
EEG basic to practice 2
EEG basic to practice 2
EEG basic to practice 2
EEG basic to practice 2
EEG basic to practice 2
EEG basic to practice 2

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EEG basic to practice 2

  • 2. To learn together FIRST One flower can give an odour enough than a bouquet But can’t give the colorful collection SECOND Our aim and objectives
  • 6. EEG Waves • ‫د‬‫ايما‬‫ت‬‫أتى‬‫ا‬‫لرياح‬‫ب‬‫ياتا‬ • Delta waves – 1 – 3.5 Hz. • Theta wave -- 4 – 7.5 Hz. • Alpha wave -- 8 – 13 Hz. • Beta wave -- >13 Hz. (14 – 30 Hz.) »D T A B
  • 8. Alpha Rhythm ‫أ‬‫المخ‬ ‫فى‬ ‫حاجة‬ ‫خر‬-‫ا‬‫صحى‬-‫ا‬‫تتأكد‬ ‫عنيك‬ ‫قفل‬–‫ا‬‫مهم‬ ‫لفرق‬ • The starting point of analysing awake EEG • 8-13 Hz activity occurring during wakefulness • 20-60 mV, max over posterior head regions, Waxing & waning • Present when eyes closed; blocked by eye opening or alerting the patient • 8 Hz is reached by 3 years of age and progressively increases in a stepwise fashion until 9-12 Hz is reached by adolescence • Very stable in an individual, rarely varying by more than 0.5 Hz. • With drowsiness, alpha activity may decrease by 1-2 Hz • A difference of greater than 1 Hz between the two hemispheres is significant.( Ear referential montage) • 10% of adult have little or no alpha
  • 12. NB • Unilateral failure of the alpha rhythm to attenuate reflects an ipsilateral abnormality (Bancaud’s phenomenon). • Normally, alpha frequencies may transiently increase immediately after eye closure (alpha squeak). • Alpha variants include forms that are one-half (slow alpha) • or two times the frequency with similar distribution and reactivity. (fast alpha) • Alertness results in the presence of alpha, and drowsiness does not. Paradoxical alpha
  • 13. Mu Rhythm Arciform, apiculate negative and rounded positive phase (9-11) Hz. • - Intermingled with 20 Hz beta. C3,4 & Cz location. • - may be seen only on one side, and may be quite asymmetrical and asynchronous, despite the notable absence of an underlying structural lesion. • - Normal if other central rhythms symmetrical. • - Eyes open has no effects. • block with contralateral movement of an extremity. • - High voltage over skull defect – breach rhythm. • - Apiculate phase may resembles spikes.
  • 17. Beta wave • Faster than alpha, present in the anterior head area. • Is a normal finding in the adult awake EEG and can sometimes be better seen when patient's eyes open. • Enhanced by drowsiness and some medication especially barbiturates.14 hz and above; 15-25 Hz most common. • - - Location: frontal – common; • central common mixed with Mu. • Posterior – fast alpha variant. • Diffuse – when abundant = medication effect • - Usually < 20 mV; occasionally 20-30 mV. • - Amplitude and distribution increases by: drowsiness, light sleep, REM, skull defect, medication especially benzodiazepines, barbiturates, chloral hydrate. • - Diffuse theta may accompany medication-induced excess beta.
  • 19. Theta Rhythm • – Low voltage 4-7 hz diffuse theta a common component of normal recordings. • - May be seen at the onset of sleep, not a predominant rhythm in the normal alert adult EEG. • - More common in children and young adults than older adults. • The appearance of frontal theta can be facilitated by emotions, focused concentration, and during mental tasks. • Theta activity is normally enhanced by hyperventilation, drowsiness, and sleep. • Intermittent 4- to 5-Hz activity bitemporally, or even with a lateralized predominance (usually left > right), may occur in about one-third of the asymptomatic elderly and is not abnormal.
  • 20. Lambda waves • O1,2 pricipally. Involve P3,4 & T5,6. • Bilateral synchronous; diphasic or triphasic. • Largest wave electropositive lasting 100- 200msec. • Evoked by scanning well-illuminated, patterned visual field. • Present in 50% of normal EEGs. • Blocked by white paper shuttle
  • 22. DELTA waves • Less than 4 hz. • - Not a normal findings in the awake adult EEG. • - Normally found in the deeper stages of sleep. • - Hyperventilation Sequencies: Increase in diffuse theta. Rhythmic delta in bursts. Continuous rhythmic delta. • - Effect maximally anterior in most adolescents, adults maximum amplitude of delta bursts may shift from side-to-side. • - Multiples frequencies may create apiculate wave forms effect greatly in youth with maximum effort and low serum glucose. • - Effects subsides in 60-90secs. After HV. • - Post HV period may contain newly appearing focal delta or theta as abnormalities.
  • 29. Stages of sleep EEG pattern Somatic or Behavioral changes Alert Alpha activity on eye closed Desynchronization on eye opening Respond to verbal commands I (Drowsiness) Alpha dropout and slowing & appearance of vertex waves & theta.POSTS Reduced HR & RR II (Light sleep) Sleep spindles, vertex sharp waves & K-complexes, POSTS Reduced HR & RR III ( Deep Sleep) Much slow theta- delta background K-complexes No spindles Reduced HR & RR
  • 30. IV (very deep sleep) Synchronous delta waves, some K- complexes Reduced HR & RR REM sleep (paradoxical sleep) Desynchronization with faster frequencies Mixed frequencies HR, BP & RR irregular Marked hypotonia Rapid eye movement 50 – 60 /min. Dreaming threshold of arousal
  • 33. Wave variants with sleep • Vertex (V) Waves • – Bilaterally synchronous. • - Maximum amplitude at vertex (Cz) extend to Fz, Pz, F3,4; C3,4; P3,4. • - May appear in sequencies; shifting asymmetries occur; • - . • - May be preceded and/or followed by smaller waves of opposite polarity. • - Highest amplitude and sharpest in youth; become more blunt with age. • - Appear principally in light sleep but also in awakefulness, drowsiness, and at onset of focal pathology.
  • 34. Post Occipital Sharp Transients of Sleep (POSTs) • Sharp-contoured, mornophasic, surface-positive transients • Ocurring singly or in trains of 4-5 Hz over the occipital head regions • May have a similar appearance to the lambda waves during the awake record but are of higher voltage and longer duration • Usually bilaterally synchronous but may be asymmetric over the two sides • Predominantly seen during drowsiness and light sleep
  • 35. POSTs
  • 36. • Spindles – • Rhythmic or arciform waves. • - In 2-3 sec bursts, waxing and waning giving spindle shape. • - Bilaterally synchronous and symmetrical or asynchronous with symmetry of total spindle quantity. • - 13-14 Hz Cz, C3,4 with frontal spread in light stage 2 sleep. • - 10-12 Hz Fz, F3,4 in deeper stage 2 and stage 3 sleep.
  • 38. • K Complexes – • Diphasic waves (Initial brief wave; subsequent slow wave). • - + Spindles superimposed on slowed wave stage 2 sleep
  • 42. Stages of sleep EEG pattern Somatic or Behavioral changes Alert Alpha activity on eye closed Desynchronization on eye opening Respond to verbal commands I (Drowsiness) Alpha dropout and slowing & appearance of vertex waves & theta.POSTS Reduced HR & RR II (Light sleep) Sleep spindles, vertex sharp waves & K-complexes, POSTS Reduced HR & RR III ( Deep Sleep) Much slow theta- delta background K-complexes No spindles Reduced HR & RR
  • 43. IV (very deep sleep) Synchronous delta waves, some K- complexes Reduced HR & RR REM sleep (paradoxical sleep) Desynchronization with faster frequencies Mixed frequencies HR, BP & RR irregular Marked hypotonia Rapid eye movement 50 – 60 /min. Dreaming threshold of arousal
  • 46. Wave variants with sleep • Vertex (V) Waves • – Bilaterally synchronous. • - Maximum amplitude at vertex (Cz) extend to Fz, Pz, F3,4; C3,4; P3,4. • - May appear in sequencies; shifting asymmetries occur; • - . • - May be preceded and/or followed by smaller waves of opposite polarity. • - Highest amplitude and sharpest in youth; become more blunt with age. • - Appear principally in light sleep but also in awakefulness, drowsiness, and at onset of focal pathology.
  • 47. Post Occipital Sharp Transients of Sleep (POSTs) • Sharp-contoured, mornophasic, surface-positive transients • Ocurring singly or in trains of 4-5 Hz over the occipital head regions • May have a similar appearance to the lambda waves during the awake record but are of higher voltage and longer duration • Usually bilaterally synchronous but may be asymmetric over the two sides • Predominantly seen during drowsiness and light sleep
  • 48. POSTs
  • 49. • Spindles – • Rhythmic or arciform waves. • - In 2-3 sec bursts, waxing and waning giving spindle shape. • - Bilaterally synchronous and symmetrical or asynchronous with symmetry of total spindle quantity. • - 13-14 Hz Cz, C3,4 with frontal spread in light stage 2 sleep. • - 10-12 Hz Fz, F3,4 in deeper stage 2 and stage 3 sleep.
  • 51. • K Complexes – • Diphasic waves (Initial brief wave; subsequent slow wave). • - + Spindles superimposed on slowed wave stage 2 sleep
  • 56. Factor influencing EEG • Age – Infancy – theta, delta wave – Child – alpha formation. – Adult – all four waves. • Level of consciousness (sleep) • Sedation • Hypocapnia (hyperventilation) slow & high amplitude waves. • Hypoglycemia • Hypothermia • Low glucocorticoids Slow waves
  • 58. Hyperventillation • The usefulness of HV depends on vasoconstriction secondary to resultant decreased CO2 concentration, thus inducing relative cerebral ischemia and decreased glucose utilization. • A complain of lightheadedness or tingling in the extremities. • Even tetany secondary to hypocalcemia may occur with particularly vigorous HV. • The procedure is most effective in the young; in the elderly it has little effect. • The standard response is moderate to high-voltage, often rhythmic, delta and theta slowing with bifrontal preponderance • As a rule, HV is carried out for 3 minutes with vigorous exhalation at an increased but not particularly rapid rate. • Rapid HV moves little air and has correspondingly little effect. • After the conclusion of HV the record should return to baseline levels in about 1 minute • it is not performed in patients with pulmonary and cardiac disease.
  • 60. Photic stimulation • easily carried out with strobe units that flash for 5– 10 seconds at frequencies typically between 1 and 35 Hz. • If the response to the flash train is 1 : 1 it is termed the fundamental. • It is not unusual to see harmonic (twice the flash frequency) and/or subharmonic (half the flash frequency) responses. • If photic driving is absent on one side, it may support a diagnosis of unilateral structural disease involving the occipital region (e.g., infarction in posterior cerebral artery territory).
  • 63. Sleep deprived • Sleep deprivation is a powerful activator of epileptiform activity. • It is sometimes suggested that the subject stay up all night before his or her appointment the next morning, but a brief period of sleep may be permitted. • No caffeinated beverages are permitted, • Carry out HV early in the recording • One can expect an increase in or de novo appearance of focal epileptiform activity in about 30% of patients with epilepsy
  • 65. 1. Frequency of brain waves in sequence of DTAB, same to age progression 2. Sleep changes very important, it is a source of confusion with pathology, and a source of abused EEG and AED.

Editor's Notes

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