The paper investigates the effects of cutting tool parameters on the surface roughness of a Co28Cr6Mo medical alloy during CNC lathe machining. Optimal cutting parameters for minimum surface roughness were identified as 318 rpm for rotational speed, 0.1 mm/rev for feed rate, 0.7 mm for depth of cut, and 0.8 mm for nose radius. The study also emphasizes the significant influence of these parameters on surface finish and cost efficiency in manufacturing processes.