Ventilation in laboratory buildings accounts for a large portion of campus energy usage, between 4-8 times more than other campus buildings. Laboratory ventilation rates are typically designed between 6-10 air changes per hour for safety reasons, but these high rates significantly increase energy costs. There are opportunities to reduce ventilation rates through better laboratory practices like keeping fume hood sashes low. Electricity usage is also high in laboratories due to numerous instruments and equipment. Regulations around waste disposal and air emissions further increase operating costs of laboratory buildings. However, safety and sustainability considerations do not have to compete - they can be aligned through coordinated efforts between safety, sustainability, and laboratory professionals and staff.