The play Othello by William Shakespeare explores several key themes, including doubt versus trust, monstrous imagery, and the fallible nature of love. The central theme is the contrast between doubt and trust, as Othello's weak trust in Desdemona allows Iago to plant seeds of doubt through accusations. Shakespeare also examines the human tendency to favor the "monstrous," as Iago encourages Othello's jealousy and transforms him into a violent predator. The themes highlight humanity's flaws and the dangers of passions like jealousy.