Formulation and Development of Modified Release Biphasic Compressed Tablet of Propranolol Hydrochloride

This study focuses on the formulation and development of a modified release biphasic compressed tablet of propranolol hydrochloride to enhance patient compliance by reducing the frequency of administration. The tablet design involves an immediate release layer followed by a controlled release core, with in vitro dissolution tests showing a rapid initial drug release followed by sustained release over 12 hours. Results indicate that the developed formulation demonstrates effective drug delivery with favorable release kinetics and potential for improved therapeutic efficacy.