The document outlines a framework for analyzing structural shifts resulting from the Patient Protection and Affordable Care Act (PPACA). It discusses three core themes - federalization, risk allocation, and value-driven integration - and how the law will lead to increased federal control, a reapportionment of wealth and risk, and a shift toward more coordinated, smart, and cost-effective models of care. Key changes include a tiered system of access, reordering of insurance markets, greater transparency, payment reforms, and a move from uniform procedures to personalized healthcare. The framework is meant to assess how these structural shifts will profoundly transform the US healthcare system over time.