The endocrine system maintains homeostasis through glands that secrete hormones to regulate functions like growth, metabolism, and reproduction. It interacts with other systems through hormones. The major glands are the hypothalamus, pituitary, thyroid, parathyroids, adrenals, pancreas, ovaries/testes. For example, the pituitary controls the thyroid and reproductive organs to regulate growth and menstrual cycles. Imbalances in hormones from endocrine organs can cause diseases.