Stress can negatively impact memory through its effects on the hippocampus. The hippocampus is crucial for memory formation and highly susceptible to damage from prolonged stress. Studies have shown that long-term stress from conditions like PTSD, depression, and Cushing's disease is associated with hippocampal atrophy and memory impairment. A small study of undergraduate students found an inconclusive relationship between stress levels and short-term memory test performance, though a larger sample size may have yielded clearer results.