How scientists and artists are discovering musical patterns in protein structures.
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This document discusses how scientists are discovering musical patterns in protein structures by converting their molecular vibrations into sound. Researchers at MIT have created a "protein synthesizer" that can take a protein's structure and transform it into an audible musical composition. They have also developed techniques to take a musical composition and use it to design hypothetical new protein structures. The goal is to better understand protein folding and dynamics through analogies to music. Other researchers are exploring combining sounds of proteins with cosmic sounds, voices, and thought forms to create "neuroacoustic architecture" and "space music".
![Spider web protein music by Markus Buehler and Zhao Qin - MIT
1, 2bjy 1.00 1.008378436 1.030715836 1.042870685 1.05679907 1.197504816...;
2, 1mfr 1.00 1.004021038 1.008026787 1.009678011 1.013072195 1.345060086...;
3, 1jre 1.00 1.008745375 1.031036908 1.062318442 1.087392594 1.199064306...;
4, 1ji4 1.00 1.003761123 1.017001498 1.062119683 1.0803596 1.256459652...;
5, 1qgh 1.00 1.031281534 1.038941382 1.067944837 1.091459499 1.213160872...;
6, 1l8h 1.00 1.003180136 1.024905972 1.091780571 1.110586185 1.250007645...;
7, 1jxv 1.00 1.017980002 1.06477999 1.094991285 1.119377427 1.1889582...;
8, 1gl6 1.00 1.009662722 1.082759991 1.091428921 1.142830933 1.166131548...;
9, 1hzd 1.00 1.025563404 1.03620463 1.108292817 1.129330642 1.226722319...;
10, 1a0c 1.00 1.013072195 1.078479039 1.105632511 1.186573097 1.201082469...;
11, 1fwu 1.00 1.056248662 1.06667584 1.104730453 1.150643672 1.214812097...;
The format of the data file (attached as Supporting Information) that contains the vibrational
spectrum of all proteins analyzed is
[PROTEIN ID], [PROTEIN ID IN PDB] [f_0/f_0] [f_1/f_0] [f_2/f_0] [f_3/f_0]...;](https://image.slidesharecdn.com/pptleonardo-190912000903/85/How-scientists-and-artists-are-discovering-musical-patterns-in-protein-structures-5-320.jpg)
How scientists and artists are discovering musical patterns in protein structures.
- 1. How Scientists and Artists are Discovering Musical Patterns in Protein Structures Markus Buehler Amino acid synthesizer Prepared for Leonardo Art/Science Evening Rendezvous of 10 September 2019 – San Francisco by Willard G Van De Bogart
- 2. Beautiful Humans Anirban Bandyopadhaya https://www.beautifulhumans.info/anirban-bandyopadhyay/ Nanao BrainScientists: Anirban Bandyopadhaya Joel Sternheimer Markus Buehler Zhao Qin Hans Geesink Dirk Meijer
- 3. Anirban Bandyopadhaya - Microtubules 2014 Sound synthesis - Van De Bogart - McVeety Additional research by Stuart Hameroff and Roger Penrose
- 4. Joel Sternheimer - Theoretical physicist - France https://studiotomassarceno.org/about/tps://studiotomassaraceno.org/about/ G D V E K G K K I F I M K C S Q C H T V E K G G the first 24 amino-acids of human cytochrome C. https://www.researchgate.net/publication/281103244_EPIGENETIC_REGULATION_OF_PROTEIN_BIOSYNTHESIS_ BY_SCALE_RESONANCE_Invited_lecture Cells healing themselves with sound: Plants Animals Humans Wave dynamics Scaling waves Louis de Broglie Endorphine Signal protein
- 5. Spider web protein music by Markus Buehler and Zhao Qin - MIT 1, 2bjy 1.00 1.008378436 1.030715836 1.042870685 1.05679907 1.197504816...; 2, 1mfr 1.00 1.004021038 1.008026787 1.009678011 1.013072195 1.345060086...; 3, 1jre 1.00 1.008745375 1.031036908 1.062318442 1.087392594 1.199064306...; 4, 1ji4 1.00 1.003761123 1.017001498 1.062119683 1.0803596 1.256459652...; 5, 1qgh 1.00 1.031281534 1.038941382 1.067944837 1.091459499 1.213160872...; 6, 1l8h 1.00 1.003180136 1.024905972 1.091780571 1.110586185 1.250007645...; 7, 1jxv 1.00 1.017980002 1.06477999 1.094991285 1.119377427 1.1889582...; 8, 1gl6 1.00 1.009662722 1.082759991 1.091428921 1.142830933 1.166131548...; 9, 1hzd 1.00 1.025563404 1.03620463 1.108292817 1.129330642 1.226722319...; 10, 1a0c 1.00 1.013072195 1.078479039 1.105632511 1.186573097 1.201082469...; 11, 1fwu 1.00 1.056248662 1.06667584 1.104730453 1.150643672 1.214812097...; The format of the data file (attached as Supporting Information) that contains the vibrational spectrum of all proteins analyzed is [PROTEIN ID], [PROTEIN ID IN PDB] [f_0/f_0] [f_1/f_0] [f_2/f_0] [f_3/f_0]...;
- 6. Analogy of protein structure to musical structures – Markus Buehler http://web.mit.edu/mbuehler/www/papers/BioNanoScience_2011_3.pdf
- 7. Amino acid synthesizer by Zhao Qin and Markus Buehler MIT scientists have converted the molecular structures of proteins into audible sound that resembles musical passages. Reversing the process means they can introduce variations and convert the music back into new proteins. AI and the human
- 8. Protein Synthesizer Zhao Qin – Markus Buehler Protein synthesizer MAX plugin Quantum wave mechanics Protein Folding options Van De Bogart - DeGeorge Abelton 10 Live Geesink and Meijer
- 9. Protein synthesizer Max plugin graphical representation for Abelton Live 10 DAW
- 10. Protein Synthesizer Control Panel
- 11. “Quantum aesthetics entails the creation of both and art and a literature based on the most revolutionary findings within quantum physics and the psychology developed after it.” Maria Caro and Andrés Monteagudo The World of Quantum Culture Artists: John Dunn Willard Van De Bogart Gregorio Morales Combining sound with quantum thought forms
- 12. Protein folding model by Hans Geesink and Dirk Meijer The integration of the human brain and the quantum field
- 13. Visualizing wave dynamics in space effecting protein molecules https://www.researchgate.net/publication/315706536_The_Folding_of_a_Life_Proteins_On_the_role_of_long- and_short_range_electromagnetic_pilot_mechanisms Hans Geesink and Dirk Meijer The folding of life proteins
- 14. Life Music: https://www.jstor.org/stable/1576622?seq=1#page_scan_tab_contents John Dunn A collaboration with biologist Dr. Mary Anne Clark, produced from the primary and secondary structure of protein sequences, using software and synths. In each piece, pitch is determined by amino acid identity and instrumentation is chosen according to protein folding pattern, with different instruments representing regions of alpha-helix, beta-strands and turns. Lysozyme 254L Protein Data Base Lysozyme
- 15. Compositional techniques using electronic synthesizers Man machine interface – AI verses the human - What happens to us when we listen to the sounds of proteins
- 16. Designing sonic wave shape topologies with the AniMoog synthesizer Designing folding patterns using the AniMoog wavetable synthesizer
- 17. Creating wave shapes on a Waldorf NAVE synthesizer to a protein synthesizer
- 18. Combining sonified elements in the universe with Synthscaper synthesizer by Igor Vasliev Quasar Pulsar Comet
- 19. TH ORNG SH OW CH Creating neuroacoustic architecture Combining amino acid sounds, phonemes and scales Topological space using 44 phonemes from the English language 20 Amino Acids Erv Wilson micro tonal scale Hebdomekontany
- 20. Creating space music: combining Thought forms, Protein sounds, Sonified galactic, and Voice Quantum Thought forms Synthesizers Cosmic/Space sounds Protein Sounds Idea Instrument Direction Tone Voice xenolinguistics Individual sounds Combined sounds
- 21. The xenosphere of our existence We are at the threshold of discovering ourselves through sound