This document discusses key concepts related to the diffusion, spread, and scaling of innovations in healthcare. It begins with definitions of diffusion, spread, and going to scale. It then discusses the importance of measuring success based on a program's ability to achieve large scale and be sustained over time. The document provides examples of large scale improvement programs in the NHS that achieved widespread adoption. It also discusses common patterns observed in pilot programs that attempt to spread, such as a lack of focus on spread during the pilot, failure to engage adopters in new contexts, and sustainability challenges. Overall, the document emphasizes the importance of engaging local stakeholders, understanding different adoption patterns, and taking an adaptive approach to spreading programs based on local needs and capabilities.