Isaac Newton was born in 1643 and died in 1727. He was an influential physicist, mathematician and astronomer. During plague outbreaks in 1665-1666 that closed his university, Newton developed many of his later discoveries in isolation. He was notoriously secretive about his work and accused others of plagiarizing his ideas. Newton had antagonistic relationships with other scientists and fought over credit for his work. His university lectures were poorly attended and lacked structure. Newton developed his own inconvenient notation system and was interested in occult studies and alchemy, which may have led to mercury poisoning later in life.