The seminar presented by Mr. M.D. Harsule at G.H. Raisoni College of Engineering focuses on hand gesture recognition (HGR) as a natural form of human-machine interaction and its applications without the need for additional devices. It outlines a systematic approach to processing images using MATLAB and embedded C, including steps for feature extraction and processing for effective gesture recognition. Emphasis is placed on the progression from image acquisition to edge detection, feature extraction, and utilization of neural networks for gesture input processing.