Spreadsheet errors are a large-scale problem that can have significant negative consequences. Some examples include a company being sued for $200 million to $1 billion due to a clerical error in a spreadsheet, a CFO resigning after a single number was misrecorded causing inaccurate financial forecasts, and election results being misstated due to a faulty spreadsheet total. Spreadsheet errors stem from both qualitative issues like poor design and hidden errors, as well as quantitative mistakes in reasoning, implementation, and accidental changes. Contributing factors include a lack of organizational policies on spreadsheet development, overconfidence among developers despite potential errors, and issues that can arise from solo versus group spreadsheet development.