This document outlines a half-day tutorial on topic set size design and power analysis in information retrieval (IR) experiments. The tutorial will cover determining the number of topics for a new test collection, checking if IR experiments are overpowered or underpowered, and using Excel and R scripts for topic set size design and power analysis. It provides background on statistical significance testing concepts like t-tests, ANOVA, p-values, and type I and type II errors. The tutorial agenda includes hands-on exercises for applying paired t-tests, one-way ANOVA, and power analysis to sample IR topic-by-run matrices using Excel and R scripts.