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Debate: Increasing Access or Improving
       Mortality in Endoscopy
           Elective v Acute

         Dr Sanchoy Sarkar         FRCP. PhD

              Endoscopy Services Lead
            Consultant Gastroenterologist
                   Senior Lecturer
Content

• Improving Mortality

• Futility

• Adversely Effecting Mortality
Improving Mortality
EMERGENCY-IN-PATIENT          ELECTIVE-OPD or DAY-CASE




                Therapeutic




UPPER ENDOSCOPY                     LOWER ENDOSCOPY:
 GASTROSCOPY                        COLONOSCOPY/FLEXI
EMERGENCY & IN-PATIENT
ENDOSCOPY SERVICES
Upper GI Bleed BSG Audit
          When Things Done Badly          206 Hospitals: UK

                                          • On call: Half hospitals BUT
                                            mortality 20% lower if present

                                          • High Risk Patients (Scope 12hrs)
                                              – 1/2 scoped 24hrs

                                          • High risk Bleed lesions- treatment
                                              –   ¾ Given any endoscopic treatment
                                              –   Only 1/3 given optimal


  “Goals & Opportunities are Missed !!’   • Inappropriate Drugs
                                              – ¼ used correct use
GUT 2010(59) 1022-1029
Evolving Endoscopy Services (20 yrs)
                                                                           Daily
                               Consultant                               In-patient
Middle Grade In-Patient Lists                                                                         Sunday
             Day time
                                  plus                                  Day-Time Saturday
24/7 Rota                                                                                              Lists
                              Middle Grade                             Evening Lists lists In-patient
                               24/7 Rota                                                   Coordinator
       National Training Centre




 93 99                             06     07      09                            11     12          13




                                                       Fellow             Surv       Consultant
                                                                                     Expansion
                                             Consultant     3 Session Colonoscopy                 BCSP       Flexi
                                  Bowel                                  nurse
                                            Endoscopists       Day                                Centre   Screening
                                  Cancer
                                  Screening      x3
Expertise & Infra-structure
•   Endoscopy Training Centre & Tertiary Referral Centre

•   Personnel
     –   SpR/Fellow
     –   Consultant On-Call Rota & Consultant Endoscopists


•   Equipment
     –   Endoscopic Equipment
     –   Haemostatic Equipment (Technologies)


•   Facilities
     –   Theatre/Endoscopy Unit Access
     –   High Dependency Bleed Unit & Gastro Ward Base


•   Service provision
     –   24/7 On Call Service (Consultant & Middle Grade)
     –   In-Patient Lists (Day & Evening)
     –   Weekend In-Patient Lists


•   Back-Up
     –   Interventional Radiology
     –   Specialty Based Surgery
UGI Bleeding Mortality
            Comparison National & RLH


Mortality    1993       2007     2009   2011



National     14%        10%       N/A   N/A


RLH           5%        3%        0%    0%
ELECTIVE ENDOSCOPY
Lower Endoscopy- Screening

          Diagnostic




          Therapeutic
Screening Improving Mortality
• Colonoscopy + FOBT
  – Reduce incidence CRC by 20%
  – Reduce CRC mortality by 28%


• Flexi-Sigmoidoscopy
  – Reduced incidence by 33%
  – Reduced CRC mortality 43%
  – Saved lives (1 in 200)
Futility- E.g. Colonoscopy Surveillance
    Pathology                        Mortality

                  16                       None due to CRC
                  %
                  12
                                                                    30 day
                      8                                             6 month


                      4

                      0
                               Fit               Un-Fit (not scoped)
                          Sarkar et al: Frontline Gastroenterology 2011
Elective Endoscopy
    Emergency Readmissions & Mortality
If you have access to this article through your institution, you can view this article in OvidSP.
European Journal of Gastroenterology & Hepatology:
December 2012 - Volume 24 - Issue 12 - p 1438–1446
doi: 10.1097/MEG.0b013e3283582db0
Original Articles: Endoscopy

A multicentre study to determine the incidence,
demographics, aetiology and outcomes of 6-day
emergency readmission following day-case endoscopy
Sarkar, Sanchoya; Geraghty, Joea; Moore, Andrew R.a; Lal, Simonc;
Ramesh, Jayapald; Bodger, Keithb; CERT-N: Collaboration in
Endoscopy, Research & Training-North-West


 Readmission Rate 0.5% but if readmitted Mortality 6.8%
Adverse Events
                      TOTAL    %       Rate    Standards Details/Comments
Perforations
OGD-Therapy             1     0.1     1/1000
OGD-Diagnostic          1     0.02    1/6000
Colonoscopy-
Diagnostic              0       0       N/A
Colonoscopy-Therapy     2     0.14     1/725
Flexi-Diagnostic        3     0.08    1/1800            (




Bleeding
ERCP-Sphincterotomy     4     0.26    1/100
Post-polypectomy-
EMR                     4      0.2    1/450

OGD-Diagnostic          1     0.002   1/6000            (
Hidden Health Costs
Other Complications   No    %      Rate    Comment


CVS-Resp              16   0.1    1/1000
Arrest                2                    All OGD
Aspiration            2                    All OGD
Pneumonia             3                    All Colon
MI/ACS/Angina         8    0.05   1/2000
CVA                   1

Preciptated
Obstruction           7    0.1    1/850      All after diagnostic OGD


Bowel Prep            4    0.1    1/900
Conclusions
• Improve Mortality

   – Emergency/In-Patients: Therapeutic Upper Endoscopy
   – Elective: Asymptomatic: Lower GI Endoscopy


• Adversely Effect Mortality

   – Futility & Risk to Benefit Ratio
   – Hidden Costs; Patient safety
   – APPROPRIATENESS
Thank You




              Sanchoy.Sarkar@rlbuht.nhs.uk
       www.liverpoolgastroenterology.nhs.uk

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Increasing Access or Improving Mortality in Endoscopy

  • 1. Debate: Increasing Access or Improving Mortality in Endoscopy Elective v Acute Dr Sanchoy Sarkar FRCP. PhD Endoscopy Services Lead Consultant Gastroenterologist Senior Lecturer
  • 2. Content • Improving Mortality • Futility • Adversely Effecting Mortality
  • 3. Improving Mortality EMERGENCY-IN-PATIENT ELECTIVE-OPD or DAY-CASE Therapeutic UPPER ENDOSCOPY LOWER ENDOSCOPY: GASTROSCOPY COLONOSCOPY/FLEXI
  • 5. Upper GI Bleed BSG Audit When Things Done Badly 206 Hospitals: UK • On call: Half hospitals BUT mortality 20% lower if present • High Risk Patients (Scope 12hrs) – 1/2 scoped 24hrs • High risk Bleed lesions- treatment – ¾ Given any endoscopic treatment – Only 1/3 given optimal “Goals & Opportunities are Missed !!’ • Inappropriate Drugs – ¼ used correct use GUT 2010(59) 1022-1029
  • 6. Evolving Endoscopy Services (20 yrs) Daily Consultant In-patient Middle Grade In-Patient Lists Sunday Day time plus Day-Time Saturday 24/7 Rota Lists Middle Grade Evening Lists lists In-patient 24/7 Rota Coordinator National Training Centre 93 99 06 07 09 11 12 13 Fellow Surv Consultant Expansion Consultant 3 Session Colonoscopy BCSP Flexi Bowel nurse Endoscopists Day Centre Screening Cancer Screening x3
  • 7. Expertise & Infra-structure • Endoscopy Training Centre & Tertiary Referral Centre • Personnel – SpR/Fellow – Consultant On-Call Rota & Consultant Endoscopists • Equipment – Endoscopic Equipment – Haemostatic Equipment (Technologies) • Facilities – Theatre/Endoscopy Unit Access – High Dependency Bleed Unit & Gastro Ward Base • Service provision – 24/7 On Call Service (Consultant & Middle Grade) – In-Patient Lists (Day & Evening) – Weekend In-Patient Lists • Back-Up – Interventional Radiology – Specialty Based Surgery
  • 8. UGI Bleeding Mortality Comparison National & RLH Mortality 1993 2007 2009 2011 National 14% 10% N/A N/A RLH 5% 3% 0% 0%
  • 10. Lower Endoscopy- Screening Diagnostic Therapeutic
  • 11. Screening Improving Mortality • Colonoscopy + FOBT – Reduce incidence CRC by 20% – Reduce CRC mortality by 28% • Flexi-Sigmoidoscopy – Reduced incidence by 33% – Reduced CRC mortality 43% – Saved lives (1 in 200)
  • 12. Futility- E.g. Colonoscopy Surveillance Pathology Mortality 16 None due to CRC % 12 30 day 8 6 month 4 0 Fit Un-Fit (not scoped) Sarkar et al: Frontline Gastroenterology 2011
  • 13. Elective Endoscopy Emergency Readmissions & Mortality If you have access to this article through your institution, you can view this article in OvidSP. European Journal of Gastroenterology & Hepatology: December 2012 - Volume 24 - Issue 12 - p 1438–1446 doi: 10.1097/MEG.0b013e3283582db0 Original Articles: Endoscopy A multicentre study to determine the incidence, demographics, aetiology and outcomes of 6-day emergency readmission following day-case endoscopy Sarkar, Sanchoya; Geraghty, Joea; Moore, Andrew R.a; Lal, Simonc; Ramesh, Jayapald; Bodger, Keithb; CERT-N: Collaboration in Endoscopy, Research & Training-North-West Readmission Rate 0.5% but if readmitted Mortality 6.8%
  • 14. Adverse Events TOTAL % Rate Standards Details/Comments Perforations OGD-Therapy 1 0.1 1/1000 OGD-Diagnostic 1 0.02 1/6000 Colonoscopy- Diagnostic 0 0 N/A Colonoscopy-Therapy 2 0.14 1/725 Flexi-Diagnostic 3 0.08 1/1800 ( Bleeding ERCP-Sphincterotomy 4 0.26 1/100 Post-polypectomy- EMR 4 0.2 1/450 OGD-Diagnostic 1 0.002 1/6000 (
  • 15. Hidden Health Costs Other Complications No % Rate Comment CVS-Resp 16 0.1 1/1000 Arrest 2 All OGD Aspiration 2 All OGD Pneumonia 3 All Colon MI/ACS/Angina 8 0.05 1/2000 CVA 1 Preciptated Obstruction 7 0.1 1/850 All after diagnostic OGD Bowel Prep 4 0.1 1/900
  • 16. Conclusions • Improve Mortality – Emergency/In-Patients: Therapeutic Upper Endoscopy – Elective: Asymptomatic: Lower GI Endoscopy • Adversely Effect Mortality – Futility & Risk to Benefit Ratio – Hidden Costs; Patient safety – APPROPRIATENESS
  • 17. Thank You Sanchoy.Sarkar@rlbuht.nhs.uk www.liverpoolgastroenterology.nhs.uk