The HCI course aims to impart knowledge on user interface design, evaluation, and research problems, enhancing students' portfolios with practical projects like a user study and final interface design. It covers fields such as computer science, psychology, and design, focusing on creating usable and universally accessible interfaces for diverse user needs. The course emphasizes the importance of usability in various applications, addressing challenges such as cultural diversity, accessibility for users with disabilities, and the impact of design on user experience.