This document proposes a statistical approach to save energy in cloud computing through predictive monitoring and optimization techniques. It discusses using Gaussian process regression to predict infrastructure workload and then applying convex optimization to determine the optimal subset of physical machines needed. Virtual machines would be migrated to this subset and idle physical machines could then be powered off to reduce energy consumption while maintaining system performance. An evaluation using 29 days of Google trace data showed the potential for significant power savings without affecting quality of service.