The document proposes a new quadtree-based algorithm for multi-focus image fusion. The algorithm divides the input images into 4 equal blocks using a quadtree structure. It then further divides each block into smaller blocks and detects the focused regions in each block using a focus measure and weighted values. The small blocks are then fused using a modified Laplacian mechanism. The fused image is evaluated using SSIM and ESSIM values, which indicate the proposed algorithm performs better fusion than previous methods.