This document describes the design and development of a vapor compression refrigeration system using a liquid heat exchanger. The system uses refrigerant blends of R600a and R290 or HFO-1234yf to increase the system's coefficient of performance (COP) while reducing global warming and ozone depletion potential compared to traditional systems using R134a. Using a liquid heat exchanger reduces the load on the compressor, allowing for greater cooling effect with lower energy input and less environmental harm. Testing confirmed the new system achieved a COP increase while lowering global warming potential to around 4, compared to 1300 for R134a, and maintaining an ozone depletion potential of zero.