Is the following statement true or false and why this sta.pdf
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The statement is analyzing the effects of increased 2,3-BPG in red blood cells without pyruvate kinase. It suggests that this increase stabilizes the hemoglobin T-state, allowing for enhanced oxygen release to surrounding tissues despite a lower number of red blood cells. The accuracy of this claim hinges on the physiological roles of 2,3-BPG, hemoglobin states, and the function of red blood cells in oxygen transport.
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Is the following statement true or false and why this sta.pdf
- 1. Is the following statement true or false, and why? (this statement regards anaerobic glycolysis in red blood cells) "In the absence of pyruvate kinase, 2,3-BGP increases from the Phosphoglycerate Mutase reaction, and it binds to the Hb, stabilizing the T-state, surrounding tissues receive more O2 despite there being fewer RBCs to carry O2."