Java EE 6 and GlassFish v3 aim to pave the path for the future by right-sizing the Java EE platform, making it more extensible, and easier to develop on. Key changes include introducing profiles like the Web Profile, pruning unused technologies, embracing open source frameworks, and continuing to improve the annotation-based programming model. GlassFish v3 is the reference implementation of Java EE 6 and includes new features like modular architecture, embeddability, and RESTful monitoring and management interfaces.