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Statistics One
Lecture 1
Experimental Research
1
Three Segments
•  Example 1: Polio Vaccine
•  Example 2: Memory Training
•  The concept of random

2
Lecture 1 ~ Segment 1
Example 1: Polio Vaccine

3
Polio Vaccine
•  In the first half of the
century there
were approximately 20,000 cases of polio
per year in the USA
•  In 1952, there were 58,000 cases
th
20

4
Polio Vaccine
•  In 1952, the first effective polio vaccine was
developed by Dr. Jonas Salk
–  How do we know that it was effective?
•  Experimental research!
•  Randomized Controlled Experiments

5
Polio Vaccine
•  Sample

–  Initial

•  4,000 children from Virginia

–  Final

•  1.8 million children from 44 states

•  Population

–  All children in the USA
6
Polio Vaccine
•  Independent variable
–  Treatment
•  Vaccine
•  Placebo

•  Dependent variable
–  Polio diagnosis (measure of an individual child)
–  Rate of polio (measure of a group of children)
7
Polio Vaccine
•  Double-blind experiment
–  Experimenter did not know if the treatment was
vaccine or placebo
–  Child (and parents) did not know if the
treatment was vaccine or placebo

8
Polio Vaccine
•  Results
–  Rate (per 100,000)
•  Treatment: 28
•  Control: 71

9
Polio Vaccine
•  By 1994 polio had been completely
eradicated from all the Americas

10
Segment Summary
•  The major benefit of randomized
experiments is they allow for strong claims
about causality
–  Why stuff happens!
•  Predict stuff
•  Prevent bad stuff
•  Promote good stuff
11
Segment Summary
•  Strong causal claims require:
–  True independent variables
–  Random and representative samples
–  No confounds (impossible, but we try our best)

12
END SEGMENT

13
Lecture 1 ~ Segment 2
Example 2: Memory Training

14
Memory Training
•  Is it possible for adults to enhance their
intelligence by training their working
memory?
–  Promote good stuff!

15
Memory Training
•  Sample
–  College students

•  Population
–  Healthy adults

16
Memory Training
•  Independent variable
–  Training
•  Memory training
•  No training

•  Dependent variable
–  Gain in score on an intelligence test
•  IQ gain
17
Memory Training
•  Procedure
–  Treatment group engaged in memory training
for a half hour every day for weeks
•  See next slide

–  IQ
•  All subjects completed a test of intelligence before
and after training
18
Memory Training

19
Memory Training

20
Memory Training

21
Memory Training
•  Does it really work?
–  Potential confounds?

22
Segment Summary
•  The major benefit of randomized
experiments is they allow for strong claims
about causality
–  Why stuff happens!
•  Predict stuff
•  Prevent bad stuff
•  Promote good stuff
23
Segment Summary
•  Strong causal claims require:
–  True independent variables
–  Random and representative samples
–  No confounds (impossible, but we try our best)

24
END SEGMENT

25
Lecture 1 ~ Segment 3
The concept of random

26
Random
•  Experimental research requires:
–  Random selection
–  Random assignment

27
Random
•  Random selection
–  Individuals included in a sample should be
randomly selected from the population

28
Illustration

29
Random

30
Not random

31
Random
•  Random assignment
–  Individuals are randomly assigned to conditions

32
Random assignment
Group 1

Group 2

33
Segment Summary
•  Experimental research requires:
–  Random selection
–  Random assignment

34
END SEGMENT

35
END LECTURE 1

36

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