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UCMC Spine Conference
Metastatic Disease to the Spine
June 6th, 2014
(from Greek
προστάτης,
prostates,
literally "one who
stands before",
"protector",
"guardian"
Lecture spine metastatic_prostate 2014 june
One in seven lifetime risk USA
1 out of 35 men die from prostate
cancer
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
PSA
Lecture spine metastatic_prostate 2014 june
11/21/12
80 year
old man
with fall
and LBP R
sciatica
Lecture spine metastatic_prostate 2014 june
11/22/12
11/23/12
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
Video
11/29/12 L4 kyphoplasty for fracture with R L2L5 decompression
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
12/28/12
12/28/12
12/28/12
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
3/5/14 Dx prostate cancer
3/6/14
Lecture spine metastatic_prostate 2014 june
Readmitted through the ER 2
months later on 5/10/14 due to
inability to ambulate from
intractable LBP
Not able to care for himself at
home.
Bone scan 5/13/14 stage 4 prostate ca; frontal skull, ribs L1, R6,R7, Prox R femur, L iliac, L1?
Lecture spine metastatic_prostate 2014 june
Skeletal met of unknown origin
• 40 patients prospective
• CT chest/abd/pelvis 75%
• H&P: 8%
• CXR: 43%
• CT chest 15%
• Ct Abd 13%
• f/u CT 5%
• Tissue: 8%
• 85% chance of finding Dx preop with studies
• LABS: SPEP
• Avoid primary sarcoma, better biopsy area, renal cell
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
Spine Conference
6/6/14
Pathology
A. E. Seiguer, M.D.
W.H.
S14-3034, 5/22/14
L1 fracture biopsy
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
PSA
PSA
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
Lecture spine metastatic_prostate 2014 june
Most Common Mets
to Bone
• Breast
• Prostate
• Lung
• Renal
• Hematopoietic tumors
• Thyroid
Lecture spine metastatic_prostate 2014 june
86 YEAR
OLD
WOMAN
LBP FALL
Lecture spine metastatic_prostate 2014 june
HETEROGENEOUS
Lecture spine metastatic_prostate 2014 june
THANKS!!

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Lecture spine metastatic_prostate 2014 june