This study analyzed differences in life satisfaction among science students at North-Eastern Hill University in India. 331 students completed the Satisfaction with Life Scale. Results found significant differences in life satisfaction between male and female students, tribal and non-tribal students, native Meghalaya students and other community students, and students from Meghalaya and other states. No significant differences were found between hostellers and non-hostellers or between students in different semesters or schools. The study contributes to understanding differences in life satisfaction among university student groups.