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© Copyright 2014. Apps Associates LLC. 1
Big Data makes a Big Difference for Life Sciences
4 September, 2014
Fran Daly
Sr. Director, Life Sciences
Apps Associates LLC
Julian Troake
Marketing Director
Apps Associates LLC
© Copyright 2014. Apps Associates LLC. 2Source: IBM
Agenda
• What is Big Data?
• Why Big Data?
• Use Cases for Big Data in Life Sciences Industry
– Product Development, Clinical, Commercial
• Technology for Big Data
• Building Big Data Capabilities in your Organization
• About Apps Associates
© Copyright 2014. Apps Associates LLC. 3
90%
Of the world’s data has been created in the last two years
Source: IBM
Explosion of Data!
Source: Gartner’s 2013 Big Data Survey
© Copyright 2014. Apps Associates LLC. 4
30%
of companies have
invested in big data
technology
Source: Gartner’s 2013 Big Data Survey
8%
of companies have
deployed big data
solutions
Big Data Adoption
© Copyright 2014. Apps Associates LLC. 5
What is Big Data?
CRM
Volume, Velocity,
Variety
Clinical /
EHR RFID
Website
Log files
Social
Media
Medicare
ClaimsRx
Images,
diagnostics
Documents,
surveys, email
unstructured,
structured, streaming
Genomic
data
© Copyright 2014. Apps Associates LLC. 6
Transportation & Logistics
Medical &
Healthcare
Industrial & Energy
AWS Big data
Infrastructure
Security & Surveillance
Amazon Kinesis
Amazon
Redshift
Amazon EMR
Big Data and the Internet of Things
© Copyright 2014. Apps Associates LLC. 7
• Cloud Computing Infrastructure
─ Unlimited capacity on demand
─ Auto-scaling / parallel processing
─ Low cost / no initial h/w investment
• Open source tools
─ Hadoop / map reduce technology
─ Analytics
─ GATK (Genomic Analytics)
─ No sql databases
• High speed communications (internet, mobile, wireless)
Big Data Enablers
© Copyright 2014. Apps Associates LLC. 8
Be the 15%!
Through 2015, 85% of Fortune 500 companies will be
unable to exploit big data for competitive advantage
-Gartner
Competitive Advantage
Why Big Data?
© Copyright 2014. Apps Associates LLC. 9
• Genomic sequencing, annotation and analysis
• Personalized medicine – 360 view of patient
• New revenue streams – patient monitoring
• Simulation / modeling
• Academic databases / basic research
• Collaborative authoring / Internal Facebook
sites
Product Development Use Cases for Big Data
© Copyright 2014. Apps Associates LLC. 10
• Precisely targeted Patient Recruitment
• Real Time Clinical Trial Analytics
─ Physician sign up
─ Site Activation
─ Monitoring key milestone progress
─ Data deficiencies
• Earlier adverse reaction signaling / detection
• Sooner protocol / treatment problem
detection
• Clinical Supply Management
• Device failures / service issues / complaints
Clinical Use Cases for Big Data
© Copyright 2014. Apps Associates LLC. 11
• Customer Support / Servicing
• Sentiment analysis – product and competition
• New Revenue Streams – patient monitoring
• Product Quality improvements – device data
• Outcome benefits measurement (ACA, Medicare, PCORB)
• Liability protection, compliance – detecting problems early on
• Operational Efficiency - self problem reporting
Commercial Use Cases for Big Data
© Copyright 2014. Apps Associates LLC. 12
Big Data Technologies
© Copyright 2014. Apps Associates LLC. 13
Amazon EMR
(Elastic Map Reduce)
Amazon Redshift AWS Data Pipeline
Hosted Hadoop
framework
Petabyte-scale data
warehouse service
Move data among AWS
services and on-
premises data sources
AWS Big Data Services
© Copyright 2014. Apps Associates LLC. 14
Exploration:
• Learning
• Use case definition
Experimentation:
• Open source tools
• Cloud computing
• Pilot projects
Large Scale Adoption:
• Data definition
• Curation
• Security, Governance
• Architecture
• Skilled resources
Incremental Approach!
Building Big Data Capabilities
© Copyright 2014. Apps Associates LLC. 15
Key Capabilities:
• Cloud Computing know how
• Data acquisition / ingestion
• Data parsing and interpretation
• Data simplification and storage
• Analysis and visualization
• Security and access provisioning
Unlocking Big Data
© Copyright 2014. Apps Associates LLC. 16
• Advanced Consulting Partner status
─ Managed Services Provider Competency
─ Oracle Competency
• Considered top partner in Oracle ecosystem /
highlighted as ~ 1-of-top 30 worldwide at AWS Summit
• Joint Oracle OEM Product Development
• Various Webinars, Presentations at OOW, re:Invent
• Successful deployment on AWS
─ Datacenter migration – Complete & Partial workloads
─ Oracle Workloads – Production, DR, Test/Dev
─ Oracle EBS, OBI, FMW – Portal, Webcenter deployments
Apps Associates & AWS
© Copyright 2014. Apps Associates LLC. 17
Web: www.appsassociates.com
Email: fran.daly@appsassociates.com | julian.troake@appsassociates.com
YouTube: www.youtube.com/user/AppsAssociates
LinkedIn: www.us.linkedin.com/company/Apps-Associates
Twitter: @AppsAssociates
Facebook: www.facebook.com/AppsAssociatesGlobal
Google+: www.plus.google.com/+AppsAssociatesGlobal/
Connect with Us
Thank You!
Clinical Trial Structured Data
• Data Entities
• Sites
• Investigators
• Patients
• Study Milestones (e.g. Site Activation, Patient Recruitment, Informed Consent,
Database Lock, etc.)
• Protocols (Treatment)
• CRAs
• Clinical data / EHR data
• Data Sources
• CT s/w Packages, e.g. Oracle Clinical, eClinica, ClinTrial):
• Feeds from CROs (Covance, Quintiles, ICON)
• Lab Data (EHR)

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Life Science Big Data Big Difference-01Sep2014

  • 1. © Copyright 2014. Apps Associates LLC. 1 Big Data makes a Big Difference for Life Sciences 4 September, 2014 Fran Daly Sr. Director, Life Sciences Apps Associates LLC Julian Troake Marketing Director Apps Associates LLC
  • 2. © Copyright 2014. Apps Associates LLC. 2Source: IBM Agenda • What is Big Data? • Why Big Data? • Use Cases for Big Data in Life Sciences Industry – Product Development, Clinical, Commercial • Technology for Big Data • Building Big Data Capabilities in your Organization • About Apps Associates
  • 3. © Copyright 2014. Apps Associates LLC. 3 90% Of the world’s data has been created in the last two years Source: IBM Explosion of Data! Source: Gartner’s 2013 Big Data Survey
  • 4. © Copyright 2014. Apps Associates LLC. 4 30% of companies have invested in big data technology Source: Gartner’s 2013 Big Data Survey 8% of companies have deployed big data solutions Big Data Adoption
  • 5. © Copyright 2014. Apps Associates LLC. 5 What is Big Data? CRM Volume, Velocity, Variety Clinical / EHR RFID Website Log files Social Media Medicare ClaimsRx Images, diagnostics Documents, surveys, email unstructured, structured, streaming Genomic data
  • 6. © Copyright 2014. Apps Associates LLC. 6 Transportation & Logistics Medical & Healthcare Industrial & Energy AWS Big data Infrastructure Security & Surveillance Amazon Kinesis Amazon Redshift Amazon EMR Big Data and the Internet of Things
  • 7. © Copyright 2014. Apps Associates LLC. 7 • Cloud Computing Infrastructure ─ Unlimited capacity on demand ─ Auto-scaling / parallel processing ─ Low cost / no initial h/w investment • Open source tools ─ Hadoop / map reduce technology ─ Analytics ─ GATK (Genomic Analytics) ─ No sql databases • High speed communications (internet, mobile, wireless) Big Data Enablers
  • 8. © Copyright 2014. Apps Associates LLC. 8 Be the 15%! Through 2015, 85% of Fortune 500 companies will be unable to exploit big data for competitive advantage -Gartner Competitive Advantage Why Big Data?
  • 9. © Copyright 2014. Apps Associates LLC. 9 • Genomic sequencing, annotation and analysis • Personalized medicine – 360 view of patient • New revenue streams – patient monitoring • Simulation / modeling • Academic databases / basic research • Collaborative authoring / Internal Facebook sites Product Development Use Cases for Big Data
  • 10. © Copyright 2014. Apps Associates LLC. 10 • Precisely targeted Patient Recruitment • Real Time Clinical Trial Analytics ─ Physician sign up ─ Site Activation ─ Monitoring key milestone progress ─ Data deficiencies • Earlier adverse reaction signaling / detection • Sooner protocol / treatment problem detection • Clinical Supply Management • Device failures / service issues / complaints Clinical Use Cases for Big Data
  • 11. © Copyright 2014. Apps Associates LLC. 11 • Customer Support / Servicing • Sentiment analysis – product and competition • New Revenue Streams – patient monitoring • Product Quality improvements – device data • Outcome benefits measurement (ACA, Medicare, PCORB) • Liability protection, compliance – detecting problems early on • Operational Efficiency - self problem reporting Commercial Use Cases for Big Data
  • 12. © Copyright 2014. Apps Associates LLC. 12 Big Data Technologies
  • 13. © Copyright 2014. Apps Associates LLC. 13 Amazon EMR (Elastic Map Reduce) Amazon Redshift AWS Data Pipeline Hosted Hadoop framework Petabyte-scale data warehouse service Move data among AWS services and on- premises data sources AWS Big Data Services
  • 14. © Copyright 2014. Apps Associates LLC. 14 Exploration: • Learning • Use case definition Experimentation: • Open source tools • Cloud computing • Pilot projects Large Scale Adoption: • Data definition • Curation • Security, Governance • Architecture • Skilled resources Incremental Approach! Building Big Data Capabilities
  • 15. © Copyright 2014. Apps Associates LLC. 15 Key Capabilities: • Cloud Computing know how • Data acquisition / ingestion • Data parsing and interpretation • Data simplification and storage • Analysis and visualization • Security and access provisioning Unlocking Big Data
  • 16. © Copyright 2014. Apps Associates LLC. 16 • Advanced Consulting Partner status ─ Managed Services Provider Competency ─ Oracle Competency • Considered top partner in Oracle ecosystem / highlighted as ~ 1-of-top 30 worldwide at AWS Summit • Joint Oracle OEM Product Development • Various Webinars, Presentations at OOW, re:Invent • Successful deployment on AWS ─ Datacenter migration – Complete & Partial workloads ─ Oracle Workloads – Production, DR, Test/Dev ─ Oracle EBS, OBI, FMW – Portal, Webcenter deployments Apps Associates & AWS
  • 17. © Copyright 2014. Apps Associates LLC. 17 Web: www.appsassociates.com Email: fran.daly@appsassociates.com | julian.troake@appsassociates.com YouTube: www.youtube.com/user/AppsAssociates LinkedIn: www.us.linkedin.com/company/Apps-Associates Twitter: @AppsAssociates Facebook: www.facebook.com/AppsAssociatesGlobal Google+: www.plus.google.com/+AppsAssociatesGlobal/ Connect with Us
  • 19. Clinical Trial Structured Data • Data Entities • Sites • Investigators • Patients • Study Milestones (e.g. Site Activation, Patient Recruitment, Informed Consent, Database Lock, etc.) • Protocols (Treatment) • CRAs • Clinical data / EHR data • Data Sources • CT s/w Packages, e.g. Oracle Clinical, eClinica, ClinTrial): • Feeds from CROs (Covance, Quintiles, ICON) • Lab Data (EHR)