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Macro and Micronutrients in
Chicken
Macronutrients:-
 Nutrients are substances needed for growth,
metabolism, and for other body functions.
Since ―macro‖ means large, macronutrients
are nutrients needed in large amounts.
 The prefix makro is from the Greek and means
big or large
 Macronutrients are nutrients that provide
calories or energy.
Macronutrients
 Water
 Carbohydrates
 Fats (lipids)
 Proteins
Water (H2O)
 Overlook when formulating rations—assumed
animals have access to good quality water
 EXTREMELY IMPORTANT
 Cheapest & most abundant nutrient
 May lose 100% of body fat, 50% of body protein
and live
 Lose 10% of body water, dehydration occurs
and may result in death
Cont..
 65-85% of body weight at birth
 45-60% of body weight at maturity
 Many tissues contain 70-90% water
Water sources
 Drinking water
 Feed
 Metabolic water produced by
oxidation of CHO, fats & proteins
Drinking water
Drinking
 Pigs = 1.5-3 gal/hd/day
 Sheep = 1-3 gal/hd/day
 Cattle = 10-14 gal/hd/day
 Horses = 10-14 gal/hd/day
 Poultry = 2 parts water:1 part feed
Feed
Moister contained in poultry feed
11 percent
Metabolic Water
Results from the oxidation of organic nutrients in
the tissues
- 1 g of carbohydrates = .6 g of water
- 1 g of protein = .4 g of water
- 1 g of fat = 1 g of water
- May account for 5-10% of total water intake
Water Loss
 Urine
 Feces
 Lungs (latent heat)/heat of evaporation
 Skin
 Egg production
Factors Affecting Water Intake
 Temperature & humidity
 Dietary factors
High moisture feeds reduce water intake
Fiber, DM intake, salt, and protein
increase water intake
Water Absorption
 Readily absorbed
 Monogastrics/Ruminants: Jejunum, Ileum,
Cecum, Large Intestine
CARBOHYDRATES (CHO)
 Definition: Hydrates of carbon formed by
combining CO2 and H2O
 photosynthesis
 Primary component found in livestock feeds
 70% of DM of forages
 80% of DM of grains
 Serve as source of energy or bulk (fiber) in the
diet
Sources of CHO
 Cereal Grains
 Most feedstuffs of plant origin are high in CHO
content
Types of CHO
 Monosaccharides: 1 sugar molecule
 Glucose
 Primary sugar body uses for fuel
 Fructose
 Found in honey (75%), fruits, and cane sugar
 Sweetest sugar
 Present in low concentrations in animal
feedstuffs
Monosaccharide (Glucose)
Contn..
 Disaccharides: 2 sugar molecules linked by a
glycosidic bond
 Lactose (galactose + glucose)
 Milk sugar
 Sucrose (fructose + glucose)
 Table sugar
 Present in higher concentrations in animal
feedstuffs
Disaccharide (Sucrose)
cont…
 Oligosaccharides: group of CHO consisting of
2-10 sugar groups
 Present in feed ingredients
 Fructooligosaccharides (Inulin)
 Galactooligosaccharides:
Cont..
 Oligosaccharides
 Not hydrolytically digested or digested by the
action of mammalian enzymes
 Fermented by beneficial bacteria present in GIT
 ―Functional Feed Ingredient‖: foodstuffs which,
apart from their normal nutritional value, are said
to help promote or sustain healthiness
 PREBIOTIC
Soybean Oligosaccharides
Fructooligosaccharides (Inulin)
Cont..
 Polysaccharides: many sugar molecules linked
by a glycosidic bond
 Starch: storage form in plants
 Cellulose: most abundant CHO in nature
 Hemicellulose: principle component of plant cell
wall
Polysaccharides
Cont..
Function of CHO
 Source of energy
 Source of heat
 Building block for other nutrients
CHO Digestion
 Dietary CHO must be converted to be absorbed
 Simple sugars (monosaccharides)
 How?
 Action of amylase enzyme
 Salivary amylase (swine, poultry)
 Intestinal amylase
 Action of other disaccharidases
 Produced by mucosal lining of duodenum
CHO Absorption
 Once simple sugars are formed, they are
absorbed rapidly by small intestine
 Then monosaccharides diffuse into the portal
vein which transports them to sites of
metabolism
LIPIDS
 Insoluble in water but soluble in organic
solvents
 Dense energy source:
 1 g fat = 9.45 kcal GE
 1 g protein = 4.5 kcal GE
 1 g CHO = 4.2 kcal GE
 Thus, fat produces 2.25 times the energy than
CHO
Lipids
 Triglyceride: primary storage form of lipids
 Saturated fatty acids: contain no double bonds
 Unsaturated fatty acids: contain 1 or more
double bonds
Sources of Lipids (EFA)
 Most feeds contain low levels
 > 10%
 Unprocessed oil seeds (soybean, cottonseed,
sunflower seed) contain up to 20% fat
 Traditionally, if additional fat is needed it is
added to the diet
 Animal fats
 Vegetable oils
Structure of lipids
Cont..
 Fats = solid at room temp = animal origin
 saturated
 Oils = liquid at room temp = plant origin
 unsaturated
Functions of Lipids
 Dietary energy supply
 Source of insulation & protection
 Source of essential fatty acids (EFA)
 Carrier for fat soluble vitamins
EFA
 Essential fatty acids (EFA): Those fatty acids that an animal
requires, but which it cannot synthesize in adequate amounts
to meet the animal’s need
 Linoleic
 Linolenic
-Arachidonic
 Physiological needs:
 Cell membrane structure
 Synthesis of prostaglandins which control blood pressure and
smooth muscle contractions
 Deficiency:
 Scaly, flaky skin (Poor feather growth)
 Poor growth
Lipid Digestion
 Occurs in the small intestine (duodenum)
 Bile produced by liver emulsifies fat
 Pancreatic lipase (enzyme) breaks apart fat for
absorption
Lipid Absorption
 Monoglycerides (MG)—absorbed into SI
mucosal cells
 Free Fatty Acids (FFA)—absorbed into SI
mucosal cells or enter blood circulation directly
 Very efficient
 Absorption rates range from 70-96%
 Generally, oils (unsaturated fats) are absorbed
more completely that fats (saturated fats)
PROTEINS
 DEFINITION: Protein are long chains of amino acids
(AA)- Formed by peptide linkages
 Amino group + carbon skeleton
 Principal constituent of organs and soft tissues
 Highest concentration of any nutrient, except water, in
the body of all living organisms and animals
 Required for life
Sources of Protein
 Most common feedstuffs contain some protein
 KEY: to combine feedstuffs into the diet so
that AA requirements are met
 e.g. Using a corn-soybean meal diet for pigs
Structure
Protein (2 AA joined by peptide
bond between carboxyl
and amino group
Categories of Protein
1. Essential Amino Acids (EAA):
 required in the diet
 cannot be synthesized at a rate sufficient to meet the
nutritional requirements
2. Nonessential AA
 animal can produce enough to meet it’s
requirements
3. Semi-essential AA
 Animal can not always produce enough to
meet its requirements
Essential AA
 PVT TIM HALL (KNOW!)
• Phenylalanine
• Valine
• Threonine
• Tryptophan
• Isoleucine
• Methionine
• Histidine
• Arginine
• Lysine
• Leucine
Critical amino acids
 Methionine
 Arginine
 Lysine
 Threonine
 Tryptophan
 Isoleucine
Limiting amino acids
 Lysine
 Methionine
 Cystine + methionine
Functions of Protein
 Basic structural units
Collagen, blood, elastin
 Body metabolism
Enzymes, hormones, immune system,
hereditary transmission
 Production
Meat, milk, skin/hair
Protein Deficiency
 Reduced growth & feed efficiency
 Infertility
 Reduced birth weights
 Reduced milk production
Protein Digestion
 Proteins must be broken down into AA for
absorption in the GIT
 Exception! Early in life (> 48 h after birth) proteins
from milk (immunoglobulin's) can be absorbed
intact across the intestinal epithelium
Monogastric Protein Digestion
 Stomach: HCl unfolds (denatures) proteins and
activates pepsinogen secreted by stomach to
pepsin
 Pepsin begins protein digestion to peptides
(short-chain proteins)
 Small intestine: enzymes (trypsin) break
peptides into AA
 AA are absorbed in anterior part of the small
intestine
 Jejunum and ileum
 AA are absorbed and transported to tissue via
blood
Specifications For Broiler Feeds(BIS Standards
2007)
No Nutrient Unit Pre Starter Starter Finisher
1 Moisture Max% 11.0 11.0 11.0
2 Crude protein Min % 23.0 22.0 20.0
3 Ether Extract Min % 3.0 3.5 4.0
4 Crude Fibre Max% 5.0 5.0 5.0
5 Acid Insoluble
Ash
Max% 2.5 2.5 2.5
6 Salt as NaCl Max % 0.5 0.5 0.5
7 Lysine Min% 1.3 1.2 1.0
8 Methionine Min% 0.5 0.5 0.45
9 Methionine+
cystine
Min% 0.9 0.9 0.85
10 Metabolizable
energy
Min%
Kcalkg
3000 3100 3200
Specifications For layer Feeds (BIS Standards 2007)
No Nutrient Unit Chick Grower Layer
Phase I
Phase II
1 Moisture Max% 11.0 11.0 11.0 11.0
2 Crude protein Min % 20.0 16.0 18.0 16.0
3 Ether Extract Min % 2.0 2.0 2.0 2.0
4 Crude Fibre Max% 7.0 9.0 9.0 10.0
5 Acid Insoluble Ash Max% 4.0 4.0 4.0 4.5
6 Salt as NaCl Max % 0.5 0.5 0.5 0.5
7 Lysine Min% 1.0 0.7 0.7 0.65
8 Methionine Min% 0.45 0.35 0.35 0.30
9 Methionine+ cystine Min% 0.7 0.6 0.6 0.55
10 Metabolizable
energy
Min%
Kcalk
2800 2500 2600 2400
Micronutrients in poultry
Micronutrients in poultry
 Minerals and vitamins are ca them.
 Minerals and Vitamins are called
micronutrients since they are needed in
SMALL amounts.
Minerals
 Inorganic components of the diet
 Can not be synthesized or decomposed by
chemical reactions
 Total mineral content is called ―ash‖
 Makes up 3-5% of the body weight
Sources of Minerals
 Forages usually considered good sources of
minerals
 Largely dependant on soil conditions
 Grains are fair source of P, but low in other
minerals
 Mineral premixes
 Mineral blocks
What do minerals do in our body?
 Influence fluid balance
 Regulate blood pressure
 Role in muscle contraction
 Direct nerve impulse transmission
 Used to make hormones
 Aids in building strong bones and teeth
 Each one has specific roles in body
Categories of Minerals
 Macro Minerals: Minerals normally present at
greater levels in animal body or needed in large
amounts in the diet (found in concentrations >
100 ppm)
 Calcium (Ca)
 Phosphorus (P)
 Sodium (Na)
 Chloride (Cl)
 Magnesium (Mg)
 Potassium (K)
 Sulfur (S)
Categories of Minerals
 Micro (Trace) Minerals: Minerals normally present at low
levels in animal body or needed in small amounts in the
diet (found in concentrations < 100 ppm)
 Cobalt (Co)
 Copper (Cu)
 Fluoride (Fl)
 Iodine (I)
 Iron (Fe)
 Manganese (Mn)
 Molybdenum (Mo)
 Selenium (Se)
 Zinc (Zn)
Functions of Mineral
 Skeletal formation and maintenance (Ca, P,
Mg, Cu, Mn)
 Protein synthesis (P, S, Zn)
 Oxygen transport (Fe, Cu)
 Fluid balance—osmotic pressure (Na, Cl, K)
 Acid-base balance regulation (Na, Cl, K)
 Activators or components of enzyme systems
(Ca, P, K, Mg, Fe, Cu, Mn, Zn)
 Mineral-Vitamin relationships (Ca, P, Co, Se)
Macro Mineral Deficiencies
Ca and P
 Loss of appetite and weakness
 Rickets (young birds )
Layers :
 Decreased egg production
 Cage layer fatigue
 Reduced egg size
 Poor shell quality
 Blood spot
 Yolk mottling
Breeders:-
 Decreased hatchability
 Poor performance of offspring
Sodium (Na) and Chloride(Cl)
 Loss of appetite, Growth retardation, poor feed
utilization
 Decrease in fluid volume
 Gonadal inactivity
 Reduced egg production & hatchability
 Cannibalism
 Molting in layers
Potassium
 Reduced appetite, depressed
growth, muscular weakness and
paralysis
 Intracellular acidosis
 Titanic seizure
 Reduced egg production and
shell quality
Magnesium
 Anorexia and depressed growth
 Poor feathering, panting and gasping
 Hrperirritabilty,tetany,muscular in coordination
 Decreased egg production, egg weight and
shell quality
Iron (Fe)
 Macrocytic and hypochromic anemia
 Low growth rate
 Poor feathering
 Depigmentation of feathers
 Embryonic mortality (9 to 15 days )
Manganese
 Perosis (chondrodystrophy)
 Thickened and enlarged hock joints
 Micromelia in breeders
 Ataxia and star gazing posture
Zinc (Zn)
 Decrease in weight of lymphoid organs
 Retarded growth in young chicks
Breeders:
Reduced hatchability, Embryonic abnormalities,
Reduced feed intake, poor feathering
Copper (Cu)
 Anemia
 Enlargement ,thickening and rupture of aorta
due to defective elastin formation
 Fragile long bones and lameness
 Shell less and misshapen eggs
 Embryonic mortality at 3-4 days
Iodine (I)
 Enlargement of thyroid gland
 Poor growth, egg production, egg size
 Abnormal lacy feathers
 Accumulation of fat
 Decreased hatchability
 Decreased sperm count
Selenium (Se)
 Exudative diathesis
 Nutritional muscular dystrophy
 Pancreatic dystrophy
Tolerance and toxic levels and symptoms and
lesions of mineral toxicity in chicken
Mineral Tolerable level Toxic level Toxic symptoms
Calcium Growers 1.2 %
Layers 5 %
Def. of Phosphorus
Def .of other minerals
(Mg,Fe,I,Zn,Mn)
Phosphorous 0.8 % (NPP) Def.of Ca, Def .of other
minerals
(Mg,Fe,I,Zn,Mn)
Sodium Layers -0.12 0.9% Reduced growth & egg
prod. ,wet litter
Chloride Layers -0.12 1.5% Reduced growth
Potassium 2.0% Wet litter
Magnesium chicks- 0.3%
Adults-0.5%
1.0% Poor growth,low egg
prod.,poor egg shell
quality
Cont..
Mineral Tolerable level Toxic level Toxic symptoms
Cobalt 10mg/kg 100mg/kg Reduced growth
Copper 300mg/kg 800mg/kg Necrosis of
liver,destrction of vit.E,
gizzard erosions
Iodine 300mg/kg 500mg/kg Goiter, reduced egg
prod., egg size and
hatchability
Iron 1000mg/kg 4500mg/kg Adsorbs vitamins
,formation of insoluble
phosphates
Manganese 2000mg/kg 4000mg/kg Poor growth
Selenium 2mg/kg 10mg/kg Poor growth, low egg
prod .
Zinc 1000mg/kg 1500mg/kg Muscular dystrophy,
reduced bone ash
Specifications For Broiler Feeds(BIS Standards 2007)
No Nutrient Unit Pre
Starter
Starter Finisher
1 Calcium Max% 1.0 1.0 1.0
2 Phosphorous
Available P
Min % 0.7
0.45
0.7
0.45
0.7
0.45
3 Manganese Min mg 100 100 100
4 Iodine Min mg 1.2 1.2 1.2
5 Iron Min mg 80.0 80.0 80.0
6 Copper Min mg 12.0 12.0 12.0
7 Selenium Min mg 0.15 0.15 0.15
8 Zinc Min mg 80.0 80.0 80.0
Specifications For layer Feeds (BIS Standards 2007)
No Nutrient Unit Chick Grower Layer
Phase I phase
II
Calcium Max% 1.0 1.0 3.0 3.5
2 Phosphorous
Available P
Min % 0.7
0.45
0.65
0.40
0.65
0.40
0.65
0.40
3 Manganese Min mg 70 60 60 60
4 Iodine Min mg 1.0 1.0 1.0 1.0
5 Iron Min mg 70 60 60 60
6 Copper Min mg 12.0 9.0 9.0 9.0
7 Selenium Min mg 0.15 0.15 0.15
8 Zinc Min mg 60 60 60 60
Mineral Absorption
 Minerals are converted to their ionic form and
absorbed in the small intestine
Vitamins
 Organic substances required by the animal in
very small amounts
 Necessary for metabolic activity but not part of
body structure
 Content varies greatly in the feed
 Requirements depend on species
Types of Vitamins
Fat-soluble vitamins
 Vit A (carotene): vision
 Vit D: Ca, P absorption
 Vit E (tocopherol): antioxidant
 Vit K (menadione): blood clotting
Vitamin A
 Discovered in 1913 by McCollum and Davis
 Essential for vision, healthy epithelial tissues,
and growth
 Sources: milk, cheese, cream, butter, eggs, liver
Beta carotene – A molecule normally can yield
two molecules of retinol
 One ICU of vitamin A =0.3mg of retinol or 0.55
mg of retinol palmitate
Forms of vitamin A
Form of vitamin Activity
Retinol 3.33 IU
Retinol acetate 2.91 IU
Retinol palmitate 1.82 IU
Beta carotene 1.67 IU
Functions
 Vision (Rhodopsin formation)
 Bone growth
 Reproduction
 Epithelial integrity
 Immunological response
Absorption, transport and metabolism
 Retinyl esters (RE) hydrolyzed into retinol &
absorbed in to mucosal cell.
 RE (liver) are hydrolyzed by enzymes n free
retinol is transported by retinol binding protein
(RBP) to tissues
 Liver contains as much as 95% of vitamin in
body
Deficiency
 Reduced growth
 Decrease in resistance to diseases
 Eye lesions and muscular in co-ordination
 Decrease in egg production
 Degeneration of mucus membrane
Vitamin D
 Named by McCollum in 1925
 The ―Sunshine Vitamin,‖ synthesized with the help of
sunlight also named as antirachitic vitamin
 Aids in mineralization of bones
 Sources: milk, butter, juices, cereal, chocolate, veal,
beef, egg yolks, and fatty fish
 One ICU of vit.D=0.025mg of vitamin D
Two forms
 Ergocaciferol ( D2) and
 Cholecalciferol ( D3),
 Cholecalciferol is more potent (30 times)
Functions
 Enhancement of intestinal absorption
 Elevates plasma Ca and P levels
 Helps in regulation of immune cell formation
Absorption, transport and metabolism
 Active form of vitamin D3 is formed in the
kidney under the influence of PTH during
reduced calcium levels
 Vitamin D is absorbed in presence of bile &
reaches rapidly to liver via circulation
Deficiency
 Rickets ,soft beak,claws,leg and other bones
 Depigmentation of feathers
 Reduced egg production
 Thin shelled or shell less eggs
 Reduced hatchability
 Embryonic mortality in chicks (18-19Days)
Vitamin E
 Discovered by Evans and Bishop in 1922
 Source: polyunsaturated plant oils (margarine and
salad dressing), green leafy vegetables, whole grains,
egg yolks, nuts, and fatty meats
 One ICU of vit.E = 1mg of dl- tocopherol acetate or
0.909 mg of dl tocopherol
Functions
 functions as an antioxidant
 Enhance disease resistance in chicken
 Involved in cell oxidation
Forms of vitamin E
Form Activity
DL-a-Tocopheryl acetate 1.00 IU
D –a-Tocopheryl acetate 1.36 IU
D-a-Tocopherol 1.49 IU
DL-a-Tocopherol 1.10 IU
D-v-Tocopherol 0.07 IU
Tocotrienols 1.30 IU
Deficiency
 Exudative diathesis
 Encephalomalacia/crazy chick disease
 Muscular dystrophy
 Sterility in males
Vitamin K
Discovered by Henrik Dam in 1929
Main role is in synthesis of blood
clotting proteins.
Sources: liver, green leafy vegetables,
milk, and cabbage-type vegetables.
The bacteria in our GI tracts can also
make vitamin K
Forms of vitamin K
Form of vitamin Activity
Phylloquinone (K1) 100 %
Menaquinone (K2) 100 %
Menadione (K3) 60 %
Functions
 Required for blood clotting
 Prothrombin is converted to thrombin facilitate
conversion of soluble fibrinogen in to insoluble
fibrin
 Synthesis of proconvertin,plasma
thromboplastin & Stuart factor
Deficiency
 Impaired blood clotting
 Severe internal hemorrhages
 Gizzard erosion
Water soluble
 Thiamine
 Riboflavin
 Niacin
 Pyridoxine
 Pantothenic acid
 Biotin
 Choline
 Folic acid
 Vitamin B12
 Vitamin C
Thiamine (B1)
 Discovered by Eijkman in 1897
 Essential for release of energy from nutrients
during oxidation
 Plays important role in nucleic acid synthesis
 Essential for membrane integrity and function
of nerve cell
 Concerned in synthesis of acetyl choline &
fatty acids
Sources
 Cereal byproducts like rice germ, wheat bran,
peanut meal, cane molasses and alfalfa
Deficiency
 Polyneuritis
 Loss of appetite
 Opisthotonous
 Cardiac abnormalities
 Star gazing and frequent convulsions
Riboflavin (B2)
 Discovered by Warburg and Christian in 1932
 Essential for generation of energy during the
metabolism of CHO and fats
 Facilitate biological oxidation –reduction reactions
 Sources :-
 Yeast ,liver, milk and eggs
 Hence this vitamin is extremely critical and
required to be supplied in diets of chicken
Deficiency
 Curled toe paralysis
 Retarded growth, leg paralysis
 Reduced egg production
 Reduced hatchability
Niacin
 Isolated by Warburg and Christain in 1936
 Essential for release of energy from nutrients
 Important for biosynthesis of nucleic acid
 Forms of niacin
 1)Nicotinic acid
 2)Nicotinamide
 Sources:
 cereal grains and grain byproducts
 Oilseeds
 Animal protein sources
Deficiency
 Enlargement of tibiotarsal joint, poor
feathering,dematitis of feet & head
 Reduced feed intake & growth rate in chicks
 Black tongue- inflammation of mouth &
esophagus
 Loss of weight, reduced egg production &
hatchability in layers
Pyridoxine (B6 )
 Deficiency first discovered by Goldberger and
Lillee in 1926
 Requirement increases with level of
protein,aminoacids and their ratio in diet
 Supplemental vitamin B6 may be essential in corn
soya diet
 Concerned in amino acid biosynthesis and
catabolism
 Essential for synthesis of biogenic amines
 Essential for energy production from metabolism
of carbohydrates, fats and proteins
Forms of pyridoxine
 Pyridoxal
 Pyridoxol
 Pyridoxamine
Sources
 Widely distributed in most foods
viz.muscle,meats,liver green leafy material
and whole grains
Deficiency
 Characteristic posture with wings slightly
spread and head resting on ground
 Birds run aimlessly
 Reduced appetite, growth and poor feathering
 Marked increase in gizzard erosion
 Hyper excitability
 Reduction in egg production & hatchability
Pantothenic acid
 Discovered by Norris and Ringrose in 1930
 Sensitive to moist heat-pelleting may cause loss
 Plays important role in the form of coenzyme A &
acetyl carrier protein
 Enhances antibody titers by incorporation of
amino acids in blood & albumin
 Essential for synthesis of acetyl choline
 Biosynthesis of hemoglobin
 Forms of Pantothenic acid
D-Pantothenate
DL-Pantothenate
Sources
 Cereal byproducts like rice germ, wheat bran,
peanut meal, cane molasses and alfalfa
Deficiency
 Reduced growth & poor feed conversion
 Poor feathering
 Dermatitis at the corner and near the beak
 Dermatitis of feet
 Reduced hatchability & embryonic mortality
during last phase of incubation
 Edematous embryos with subcutaneous
hemorrhages
Folacin
 Deficiency symptoms first recorded by Wills in
1951
 Sensitive to light & heat
 High protein diets infested with moulds &
supplementation of diets with sulpha drugs
increases the dietary requirement
Forms of Folacin
Folic acid
Polyglutamyl folacins
Function:
Plays key role in transfer of single carbon units
as tetrahydropholic acid
Required for maintaining immune system
Deficiency
 Anemia ,poor growth
 Depigmentation of colored feathers
 Poor hatchability & increased embryonic
mortality during last days of incubation
 Abnormal development of hyaline cartilage
Biotin (vitamin H)
 Discovered by Allison, Hoover and Burk in 1933
 Bioavalabity more from vegetable feed ingredients
than animal sources available in two forms as D-
Biotin and DL-Biotin
 Pelleting has little effect on biotin content in the
feeds
 Involved in conversion of CHO to proteins
 Essential for normal blood glucose level
 Functions in transcarboxilation ,protein
synthesis,deamination and nucleic acid
metabolism
 Coenzyme in metabolism of linoleic acid
Deficiency
 Utilization of biotin reduced if feed contains
mould or rancid fats
 Poor growth & feed efficiency,ataxia,crooked
legs & parrot beak
 Dermatitis, disturbed & broken feathers
 Reduced hatchability in breeders
Cynocobalamine(B 12)
 Identified as unknown factor by Minor &
Murphy in 1926
 Found in abundance in plant feed ingredients
 Cobalt is integral part of the vitamin(4.5%)
 Functions
 Transamination & biosynthesis of nutrients like
choline,methionine & Folacin
 Concerned in synthesis of purines,pyrimidines
& proteins
Deficiency
 Reduced hatchability & embryonic mortality
 Anemia, gizzard erosions ,fattiness of heart
liver & kidney
 Reduction in egg weight
 Reduced feed intake, feed efficiency & poor
growth of feathers
 Nervous disorders
Choline
 Discovered by Strecker in 1862
 Synthesized in liver, highly hygroscopic
 Requirement increases with increase levels of
dietary protein or fat
 Functions
 Structural component of cell
 Constituent of phospholipids, plays important
role in metabolism
 Prevents fatty liver by mobilization of fat as
lecithin
Sources
 Fish ,cereal products & oil seed meals
Deficiency
 Perosis in young chicks
 Fatty liver
Vitamin c (Ascorbic acid)
 1747 James lind ,Scottish Naval Surgeon Discovered
 Two forms Reduced form Ascorbic Acid &
dehydroxyascorbic acid
 Reduced form oxidized to dehydroascorbic acid
 Readily destroyed by oxidation
 Functions
 Collagen synthesis
 Electron transfer in the cell
 Important role in metabolism of tyrosine
 Stimulate phagocytic activity & antibody formation
 Synthesis of carnitine
 Essential for steroid synthesis
Toxicity of vitamin A,D3 & E
Vitamin Toxic level Symptoms
/lesions
A 2,000,000 IU/kg Antagonizes
absorption of
vitamin D3 & E
D3 300,000 IU/kg Hypercalcimia,mine
ralization of soft
tissue
E 40,000 IU/Kg Poor growth ,soft
tissue
mineralization
Specifications For Broiler Feeds(BIS Standards 2007)
No Nutrient Unit Pre Starter Starter Finisher
1 Vitamin A Min IU 11000 11000 10000
2 Vitamin D3 Min IU 3000 3000 300
3 Vitamin B1 Min mg 2.5 2.5 2.5
4 Vitamin B2 Min mg 6.0 6.0 6.0
5 Pantothenic acid Min mg 15.0 15.0 15.0
6 Niacin Min mg 40.0 40.0 40.0
7 Biotin Min mg 0.15 0.15 0.15
8 Vitamin B12 Min mg 0.015 0.015 0.015
9 Folic acid Min mg 1.0 1.0 1.0
10 Choline Min mg 500 500 500
11 Vitamin E Min mg 30.0 30.0 30.0
12 Vitamin K Min mg 1.5 1.5 1.5
13 Vitamin B6 Min mg 5.0 5.0 5.0
14 Linoleic acid % 1.1 1.1 1.1
Specifications For layer Feeds (BIS Standards 2007)
No Nutrient Unit Chick Grower Layer phase I phase II
1 Vitamin A Min IU 9000 8000 8000 8000
2 Vitamin D3 Min IU 1800 1600 1600 1600
3 Vitamin B1 Min mg 2.0 1.5 1.0 1.0
4 Vitamin B2 Min mg 6.0 5.0 5.0 5.0
5 Pantothenic acid Min mg 10.0 9.0 7.0 7.0
6 Niacin Min mg 40.0 20.0 20.0 20.0
7 Biotin Min mg 0.10 0.10 0.10 0.10
8 Vitamin B12 Min mg 0.010 0.008 0.008 0.008
9 Folic acid Min mg 1.0 0.5 0.5 0.5
10 Choline Min mg 500 200 400 400
11 Vitamin E Min mg 15.0 10.0 10.0 10.0
12 Vitamin K Min mg 1.5 1.5 1.5 1.5
13 Vitamin B Min mg 3.0 3.0 3.0 3.0
14 Linoleic acid % 1.0 1.0 1.0 1.0
Thank
you

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Macro and micro nutrients in chicken

  • 1. Macro and Micronutrients in Chicken Macronutrients:-  Nutrients are substances needed for growth, metabolism, and for other body functions. Since ―macro‖ means large, macronutrients are nutrients needed in large amounts.  The prefix makro is from the Greek and means big or large  Macronutrients are nutrients that provide calories or energy.
  • 3. Water (H2O)  Overlook when formulating rations—assumed animals have access to good quality water  EXTREMELY IMPORTANT  Cheapest & most abundant nutrient  May lose 100% of body fat, 50% of body protein and live  Lose 10% of body water, dehydration occurs and may result in death
  • 4. Cont..  65-85% of body weight at birth  45-60% of body weight at maturity  Many tissues contain 70-90% water
  • 5. Water sources  Drinking water  Feed  Metabolic water produced by oxidation of CHO, fats & proteins
  • 6. Drinking water Drinking  Pigs = 1.5-3 gal/hd/day  Sheep = 1-3 gal/hd/day  Cattle = 10-14 gal/hd/day  Horses = 10-14 gal/hd/day  Poultry = 2 parts water:1 part feed
  • 7. Feed Moister contained in poultry feed 11 percent
  • 8. Metabolic Water Results from the oxidation of organic nutrients in the tissues - 1 g of carbohydrates = .6 g of water - 1 g of protein = .4 g of water - 1 g of fat = 1 g of water - May account for 5-10% of total water intake
  • 9. Water Loss  Urine  Feces  Lungs (latent heat)/heat of evaporation  Skin  Egg production
  • 10. Factors Affecting Water Intake  Temperature & humidity  Dietary factors High moisture feeds reduce water intake Fiber, DM intake, salt, and protein increase water intake
  • 11. Water Absorption  Readily absorbed  Monogastrics/Ruminants: Jejunum, Ileum, Cecum, Large Intestine
  • 12. CARBOHYDRATES (CHO)  Definition: Hydrates of carbon formed by combining CO2 and H2O  photosynthesis  Primary component found in livestock feeds  70% of DM of forages  80% of DM of grains  Serve as source of energy or bulk (fiber) in the diet
  • 13. Sources of CHO  Cereal Grains  Most feedstuffs of plant origin are high in CHO content
  • 14. Types of CHO  Monosaccharides: 1 sugar molecule  Glucose  Primary sugar body uses for fuel  Fructose  Found in honey (75%), fruits, and cane sugar  Sweetest sugar  Present in low concentrations in animal feedstuffs
  • 16. Contn..  Disaccharides: 2 sugar molecules linked by a glycosidic bond  Lactose (galactose + glucose)  Milk sugar  Sucrose (fructose + glucose)  Table sugar  Present in higher concentrations in animal feedstuffs
  • 18. cont…  Oligosaccharides: group of CHO consisting of 2-10 sugar groups  Present in feed ingredients  Fructooligosaccharides (Inulin)  Galactooligosaccharides:
  • 19. Cont..  Oligosaccharides  Not hydrolytically digested or digested by the action of mammalian enzymes  Fermented by beneficial bacteria present in GIT  ―Functional Feed Ingredient‖: foodstuffs which, apart from their normal nutritional value, are said to help promote or sustain healthiness  PREBIOTIC
  • 22. Cont..  Polysaccharides: many sugar molecules linked by a glycosidic bond  Starch: storage form in plants  Cellulose: most abundant CHO in nature  Hemicellulose: principle component of plant cell wall
  • 25. Function of CHO  Source of energy  Source of heat  Building block for other nutrients
  • 26. CHO Digestion  Dietary CHO must be converted to be absorbed  Simple sugars (monosaccharides)  How?  Action of amylase enzyme  Salivary amylase (swine, poultry)  Intestinal amylase  Action of other disaccharidases  Produced by mucosal lining of duodenum
  • 27. CHO Absorption  Once simple sugars are formed, they are absorbed rapidly by small intestine  Then monosaccharides diffuse into the portal vein which transports them to sites of metabolism
  • 28. LIPIDS  Insoluble in water but soluble in organic solvents  Dense energy source:  1 g fat = 9.45 kcal GE  1 g protein = 4.5 kcal GE  1 g CHO = 4.2 kcal GE  Thus, fat produces 2.25 times the energy than CHO
  • 29. Lipids  Triglyceride: primary storage form of lipids  Saturated fatty acids: contain no double bonds  Unsaturated fatty acids: contain 1 or more double bonds
  • 30. Sources of Lipids (EFA)  Most feeds contain low levels  > 10%  Unprocessed oil seeds (soybean, cottonseed, sunflower seed) contain up to 20% fat  Traditionally, if additional fat is needed it is added to the diet  Animal fats  Vegetable oils
  • 32. Cont..  Fats = solid at room temp = animal origin  saturated  Oils = liquid at room temp = plant origin  unsaturated
  • 33. Functions of Lipids  Dietary energy supply  Source of insulation & protection  Source of essential fatty acids (EFA)  Carrier for fat soluble vitamins
  • 34. EFA  Essential fatty acids (EFA): Those fatty acids that an animal requires, but which it cannot synthesize in adequate amounts to meet the animal’s need  Linoleic  Linolenic -Arachidonic  Physiological needs:  Cell membrane structure  Synthesis of prostaglandins which control blood pressure and smooth muscle contractions  Deficiency:  Scaly, flaky skin (Poor feather growth)  Poor growth
  • 35. Lipid Digestion  Occurs in the small intestine (duodenum)  Bile produced by liver emulsifies fat  Pancreatic lipase (enzyme) breaks apart fat for absorption
  • 36. Lipid Absorption  Monoglycerides (MG)—absorbed into SI mucosal cells  Free Fatty Acids (FFA)—absorbed into SI mucosal cells or enter blood circulation directly  Very efficient  Absorption rates range from 70-96%  Generally, oils (unsaturated fats) are absorbed more completely that fats (saturated fats)
  • 37. PROTEINS  DEFINITION: Protein are long chains of amino acids (AA)- Formed by peptide linkages  Amino group + carbon skeleton  Principal constituent of organs and soft tissues  Highest concentration of any nutrient, except water, in the body of all living organisms and animals  Required for life
  • 38. Sources of Protein  Most common feedstuffs contain some protein  KEY: to combine feedstuffs into the diet so that AA requirements are met  e.g. Using a corn-soybean meal diet for pigs
  • 39. Structure Protein (2 AA joined by peptide bond between carboxyl and amino group
  • 40. Categories of Protein 1. Essential Amino Acids (EAA):  required in the diet  cannot be synthesized at a rate sufficient to meet the nutritional requirements 2. Nonessential AA  animal can produce enough to meet it’s requirements 3. Semi-essential AA  Animal can not always produce enough to meet its requirements
  • 41. Essential AA  PVT TIM HALL (KNOW!) • Phenylalanine • Valine • Threonine • Tryptophan • Isoleucine • Methionine • Histidine • Arginine • Lysine • Leucine
  • 42. Critical amino acids  Methionine  Arginine  Lysine  Threonine  Tryptophan  Isoleucine
  • 43. Limiting amino acids  Lysine  Methionine  Cystine + methionine
  • 44. Functions of Protein  Basic structural units Collagen, blood, elastin  Body metabolism Enzymes, hormones, immune system, hereditary transmission  Production Meat, milk, skin/hair
  • 45. Protein Deficiency  Reduced growth & feed efficiency  Infertility  Reduced birth weights  Reduced milk production
  • 46. Protein Digestion  Proteins must be broken down into AA for absorption in the GIT  Exception! Early in life (> 48 h after birth) proteins from milk (immunoglobulin's) can be absorbed intact across the intestinal epithelium
  • 47. Monogastric Protein Digestion  Stomach: HCl unfolds (denatures) proteins and activates pepsinogen secreted by stomach to pepsin  Pepsin begins protein digestion to peptides (short-chain proteins)  Small intestine: enzymes (trypsin) break peptides into AA  AA are absorbed in anterior part of the small intestine  Jejunum and ileum  AA are absorbed and transported to tissue via blood
  • 48. Specifications For Broiler Feeds(BIS Standards 2007) No Nutrient Unit Pre Starter Starter Finisher 1 Moisture Max% 11.0 11.0 11.0 2 Crude protein Min % 23.0 22.0 20.0 3 Ether Extract Min % 3.0 3.5 4.0 4 Crude Fibre Max% 5.0 5.0 5.0 5 Acid Insoluble Ash Max% 2.5 2.5 2.5 6 Salt as NaCl Max % 0.5 0.5 0.5 7 Lysine Min% 1.3 1.2 1.0 8 Methionine Min% 0.5 0.5 0.45 9 Methionine+ cystine Min% 0.9 0.9 0.85 10 Metabolizable energy Min% Kcalkg 3000 3100 3200
  • 49. Specifications For layer Feeds (BIS Standards 2007) No Nutrient Unit Chick Grower Layer Phase I Phase II 1 Moisture Max% 11.0 11.0 11.0 11.0 2 Crude protein Min % 20.0 16.0 18.0 16.0 3 Ether Extract Min % 2.0 2.0 2.0 2.0 4 Crude Fibre Max% 7.0 9.0 9.0 10.0 5 Acid Insoluble Ash Max% 4.0 4.0 4.0 4.5 6 Salt as NaCl Max % 0.5 0.5 0.5 0.5 7 Lysine Min% 1.0 0.7 0.7 0.65 8 Methionine Min% 0.45 0.35 0.35 0.30 9 Methionine+ cystine Min% 0.7 0.6 0.6 0.55 10 Metabolizable energy Min% Kcalk 2800 2500 2600 2400
  • 51. Micronutrients in poultry  Minerals and vitamins are ca them.  Minerals and Vitamins are called micronutrients since they are needed in SMALL amounts.
  • 52. Minerals  Inorganic components of the diet  Can not be synthesized or decomposed by chemical reactions  Total mineral content is called ―ash‖  Makes up 3-5% of the body weight
  • 53. Sources of Minerals  Forages usually considered good sources of minerals  Largely dependant on soil conditions  Grains are fair source of P, but low in other minerals  Mineral premixes  Mineral blocks
  • 54. What do minerals do in our body?  Influence fluid balance  Regulate blood pressure  Role in muscle contraction  Direct nerve impulse transmission  Used to make hormones  Aids in building strong bones and teeth  Each one has specific roles in body
  • 55. Categories of Minerals  Macro Minerals: Minerals normally present at greater levels in animal body or needed in large amounts in the diet (found in concentrations > 100 ppm)  Calcium (Ca)  Phosphorus (P)  Sodium (Na)  Chloride (Cl)  Magnesium (Mg)  Potassium (K)  Sulfur (S)
  • 56. Categories of Minerals  Micro (Trace) Minerals: Minerals normally present at low levels in animal body or needed in small amounts in the diet (found in concentrations < 100 ppm)  Cobalt (Co)  Copper (Cu)  Fluoride (Fl)  Iodine (I)  Iron (Fe)  Manganese (Mn)  Molybdenum (Mo)  Selenium (Se)  Zinc (Zn)
  • 57. Functions of Mineral  Skeletal formation and maintenance (Ca, P, Mg, Cu, Mn)  Protein synthesis (P, S, Zn)  Oxygen transport (Fe, Cu)  Fluid balance—osmotic pressure (Na, Cl, K)  Acid-base balance regulation (Na, Cl, K)  Activators or components of enzyme systems (Ca, P, K, Mg, Fe, Cu, Mn, Zn)  Mineral-Vitamin relationships (Ca, P, Co, Se)
  • 58. Macro Mineral Deficiencies Ca and P  Loss of appetite and weakness  Rickets (young birds ) Layers :  Decreased egg production  Cage layer fatigue  Reduced egg size  Poor shell quality  Blood spot  Yolk mottling Breeders:-  Decreased hatchability  Poor performance of offspring
  • 59. Sodium (Na) and Chloride(Cl)  Loss of appetite, Growth retardation, poor feed utilization  Decrease in fluid volume  Gonadal inactivity  Reduced egg production & hatchability  Cannibalism  Molting in layers
  • 60. Potassium  Reduced appetite, depressed growth, muscular weakness and paralysis  Intracellular acidosis  Titanic seizure  Reduced egg production and shell quality
  • 61. Magnesium  Anorexia and depressed growth  Poor feathering, panting and gasping  Hrperirritabilty,tetany,muscular in coordination  Decreased egg production, egg weight and shell quality
  • 62. Iron (Fe)  Macrocytic and hypochromic anemia  Low growth rate  Poor feathering  Depigmentation of feathers  Embryonic mortality (9 to 15 days )
  • 63. Manganese  Perosis (chondrodystrophy)  Thickened and enlarged hock joints  Micromelia in breeders  Ataxia and star gazing posture
  • 64. Zinc (Zn)  Decrease in weight of lymphoid organs  Retarded growth in young chicks Breeders: Reduced hatchability, Embryonic abnormalities, Reduced feed intake, poor feathering
  • 65. Copper (Cu)  Anemia  Enlargement ,thickening and rupture of aorta due to defective elastin formation  Fragile long bones and lameness  Shell less and misshapen eggs  Embryonic mortality at 3-4 days
  • 66. Iodine (I)  Enlargement of thyroid gland  Poor growth, egg production, egg size  Abnormal lacy feathers  Accumulation of fat  Decreased hatchability  Decreased sperm count
  • 67. Selenium (Se)  Exudative diathesis  Nutritional muscular dystrophy  Pancreatic dystrophy
  • 68. Tolerance and toxic levels and symptoms and lesions of mineral toxicity in chicken Mineral Tolerable level Toxic level Toxic symptoms Calcium Growers 1.2 % Layers 5 % Def. of Phosphorus Def .of other minerals (Mg,Fe,I,Zn,Mn) Phosphorous 0.8 % (NPP) Def.of Ca, Def .of other minerals (Mg,Fe,I,Zn,Mn) Sodium Layers -0.12 0.9% Reduced growth & egg prod. ,wet litter Chloride Layers -0.12 1.5% Reduced growth Potassium 2.0% Wet litter Magnesium chicks- 0.3% Adults-0.5% 1.0% Poor growth,low egg prod.,poor egg shell quality
  • 69. Cont.. Mineral Tolerable level Toxic level Toxic symptoms Cobalt 10mg/kg 100mg/kg Reduced growth Copper 300mg/kg 800mg/kg Necrosis of liver,destrction of vit.E, gizzard erosions Iodine 300mg/kg 500mg/kg Goiter, reduced egg prod., egg size and hatchability Iron 1000mg/kg 4500mg/kg Adsorbs vitamins ,formation of insoluble phosphates Manganese 2000mg/kg 4000mg/kg Poor growth Selenium 2mg/kg 10mg/kg Poor growth, low egg prod . Zinc 1000mg/kg 1500mg/kg Muscular dystrophy, reduced bone ash
  • 70. Specifications For Broiler Feeds(BIS Standards 2007) No Nutrient Unit Pre Starter Starter Finisher 1 Calcium Max% 1.0 1.0 1.0 2 Phosphorous Available P Min % 0.7 0.45 0.7 0.45 0.7 0.45 3 Manganese Min mg 100 100 100 4 Iodine Min mg 1.2 1.2 1.2 5 Iron Min mg 80.0 80.0 80.0 6 Copper Min mg 12.0 12.0 12.0 7 Selenium Min mg 0.15 0.15 0.15 8 Zinc Min mg 80.0 80.0 80.0
  • 71. Specifications For layer Feeds (BIS Standards 2007) No Nutrient Unit Chick Grower Layer Phase I phase II Calcium Max% 1.0 1.0 3.0 3.5 2 Phosphorous Available P Min % 0.7 0.45 0.65 0.40 0.65 0.40 0.65 0.40 3 Manganese Min mg 70 60 60 60 4 Iodine Min mg 1.0 1.0 1.0 1.0 5 Iron Min mg 70 60 60 60 6 Copper Min mg 12.0 9.0 9.0 9.0 7 Selenium Min mg 0.15 0.15 0.15 8 Zinc Min mg 60 60 60 60
  • 72. Mineral Absorption  Minerals are converted to their ionic form and absorbed in the small intestine
  • 73. Vitamins  Organic substances required by the animal in very small amounts  Necessary for metabolic activity but not part of body structure  Content varies greatly in the feed  Requirements depend on species
  • 74. Types of Vitamins Fat-soluble vitamins  Vit A (carotene): vision  Vit D: Ca, P absorption  Vit E (tocopherol): antioxidant  Vit K (menadione): blood clotting
  • 75. Vitamin A  Discovered in 1913 by McCollum and Davis  Essential for vision, healthy epithelial tissues, and growth  Sources: milk, cheese, cream, butter, eggs, liver Beta carotene – A molecule normally can yield two molecules of retinol  One ICU of vitamin A =0.3mg of retinol or 0.55 mg of retinol palmitate
  • 76. Forms of vitamin A Form of vitamin Activity Retinol 3.33 IU Retinol acetate 2.91 IU Retinol palmitate 1.82 IU Beta carotene 1.67 IU
  • 77. Functions  Vision (Rhodopsin formation)  Bone growth  Reproduction  Epithelial integrity  Immunological response
  • 78. Absorption, transport and metabolism  Retinyl esters (RE) hydrolyzed into retinol & absorbed in to mucosal cell.  RE (liver) are hydrolyzed by enzymes n free retinol is transported by retinol binding protein (RBP) to tissues  Liver contains as much as 95% of vitamin in body
  • 79. Deficiency  Reduced growth  Decrease in resistance to diseases  Eye lesions and muscular in co-ordination  Decrease in egg production  Degeneration of mucus membrane
  • 80. Vitamin D  Named by McCollum in 1925  The ―Sunshine Vitamin,‖ synthesized with the help of sunlight also named as antirachitic vitamin  Aids in mineralization of bones  Sources: milk, butter, juices, cereal, chocolate, veal, beef, egg yolks, and fatty fish  One ICU of vit.D=0.025mg of vitamin D Two forms  Ergocaciferol ( D2) and  Cholecalciferol ( D3),  Cholecalciferol is more potent (30 times)
  • 81. Functions  Enhancement of intestinal absorption  Elevates plasma Ca and P levels  Helps in regulation of immune cell formation
  • 82. Absorption, transport and metabolism  Active form of vitamin D3 is formed in the kidney under the influence of PTH during reduced calcium levels  Vitamin D is absorbed in presence of bile & reaches rapidly to liver via circulation
  • 83. Deficiency  Rickets ,soft beak,claws,leg and other bones  Depigmentation of feathers  Reduced egg production  Thin shelled or shell less eggs  Reduced hatchability  Embryonic mortality in chicks (18-19Days)
  • 84. Vitamin E  Discovered by Evans and Bishop in 1922  Source: polyunsaturated plant oils (margarine and salad dressing), green leafy vegetables, whole grains, egg yolks, nuts, and fatty meats  One ICU of vit.E = 1mg of dl- tocopherol acetate or 0.909 mg of dl tocopherol Functions  functions as an antioxidant  Enhance disease resistance in chicken  Involved in cell oxidation
  • 85. Forms of vitamin E Form Activity DL-a-Tocopheryl acetate 1.00 IU D –a-Tocopheryl acetate 1.36 IU D-a-Tocopherol 1.49 IU DL-a-Tocopherol 1.10 IU D-v-Tocopherol 0.07 IU Tocotrienols 1.30 IU
  • 86. Deficiency  Exudative diathesis  Encephalomalacia/crazy chick disease  Muscular dystrophy  Sterility in males
  • 87. Vitamin K Discovered by Henrik Dam in 1929 Main role is in synthesis of blood clotting proteins. Sources: liver, green leafy vegetables, milk, and cabbage-type vegetables. The bacteria in our GI tracts can also make vitamin K
  • 88. Forms of vitamin K Form of vitamin Activity Phylloquinone (K1) 100 % Menaquinone (K2) 100 % Menadione (K3) 60 %
  • 89. Functions  Required for blood clotting  Prothrombin is converted to thrombin facilitate conversion of soluble fibrinogen in to insoluble fibrin  Synthesis of proconvertin,plasma thromboplastin & Stuart factor
  • 90. Deficiency  Impaired blood clotting  Severe internal hemorrhages  Gizzard erosion
  • 91. Water soluble  Thiamine  Riboflavin  Niacin  Pyridoxine  Pantothenic acid  Biotin  Choline  Folic acid  Vitamin B12  Vitamin C
  • 92. Thiamine (B1)  Discovered by Eijkman in 1897  Essential for release of energy from nutrients during oxidation  Plays important role in nucleic acid synthesis  Essential for membrane integrity and function of nerve cell  Concerned in synthesis of acetyl choline & fatty acids
  • 93. Sources  Cereal byproducts like rice germ, wheat bran, peanut meal, cane molasses and alfalfa
  • 94. Deficiency  Polyneuritis  Loss of appetite  Opisthotonous  Cardiac abnormalities  Star gazing and frequent convulsions
  • 95. Riboflavin (B2)  Discovered by Warburg and Christian in 1932  Essential for generation of energy during the metabolism of CHO and fats  Facilitate biological oxidation –reduction reactions  Sources :-  Yeast ,liver, milk and eggs  Hence this vitamin is extremely critical and required to be supplied in diets of chicken
  • 96. Deficiency  Curled toe paralysis  Retarded growth, leg paralysis  Reduced egg production  Reduced hatchability
  • 97. Niacin  Isolated by Warburg and Christain in 1936  Essential for release of energy from nutrients  Important for biosynthesis of nucleic acid  Forms of niacin  1)Nicotinic acid  2)Nicotinamide  Sources:  cereal grains and grain byproducts  Oilseeds  Animal protein sources
  • 98. Deficiency  Enlargement of tibiotarsal joint, poor feathering,dematitis of feet & head  Reduced feed intake & growth rate in chicks  Black tongue- inflammation of mouth & esophagus  Loss of weight, reduced egg production & hatchability in layers
  • 99. Pyridoxine (B6 )  Deficiency first discovered by Goldberger and Lillee in 1926  Requirement increases with level of protein,aminoacids and their ratio in diet  Supplemental vitamin B6 may be essential in corn soya diet  Concerned in amino acid biosynthesis and catabolism  Essential for synthesis of biogenic amines  Essential for energy production from metabolism of carbohydrates, fats and proteins
  • 100. Forms of pyridoxine  Pyridoxal  Pyridoxol  Pyridoxamine
  • 101. Sources  Widely distributed in most foods viz.muscle,meats,liver green leafy material and whole grains
  • 102. Deficiency  Characteristic posture with wings slightly spread and head resting on ground  Birds run aimlessly  Reduced appetite, growth and poor feathering  Marked increase in gizzard erosion  Hyper excitability  Reduction in egg production & hatchability
  • 103. Pantothenic acid  Discovered by Norris and Ringrose in 1930  Sensitive to moist heat-pelleting may cause loss  Plays important role in the form of coenzyme A & acetyl carrier protein  Enhances antibody titers by incorporation of amino acids in blood & albumin  Essential for synthesis of acetyl choline  Biosynthesis of hemoglobin  Forms of Pantothenic acid D-Pantothenate DL-Pantothenate
  • 104. Sources  Cereal byproducts like rice germ, wheat bran, peanut meal, cane molasses and alfalfa
  • 105. Deficiency  Reduced growth & poor feed conversion  Poor feathering  Dermatitis at the corner and near the beak  Dermatitis of feet  Reduced hatchability & embryonic mortality during last phase of incubation  Edematous embryos with subcutaneous hemorrhages
  • 106. Folacin  Deficiency symptoms first recorded by Wills in 1951  Sensitive to light & heat  High protein diets infested with moulds & supplementation of diets with sulpha drugs increases the dietary requirement Forms of Folacin Folic acid Polyglutamyl folacins Function: Plays key role in transfer of single carbon units as tetrahydropholic acid Required for maintaining immune system
  • 107. Deficiency  Anemia ,poor growth  Depigmentation of colored feathers  Poor hatchability & increased embryonic mortality during last days of incubation  Abnormal development of hyaline cartilage
  • 108. Biotin (vitamin H)  Discovered by Allison, Hoover and Burk in 1933  Bioavalabity more from vegetable feed ingredients than animal sources available in two forms as D- Biotin and DL-Biotin  Pelleting has little effect on biotin content in the feeds  Involved in conversion of CHO to proteins  Essential for normal blood glucose level  Functions in transcarboxilation ,protein synthesis,deamination and nucleic acid metabolism  Coenzyme in metabolism of linoleic acid
  • 109. Deficiency  Utilization of biotin reduced if feed contains mould or rancid fats  Poor growth & feed efficiency,ataxia,crooked legs & parrot beak  Dermatitis, disturbed & broken feathers  Reduced hatchability in breeders
  • 110. Cynocobalamine(B 12)  Identified as unknown factor by Minor & Murphy in 1926  Found in abundance in plant feed ingredients  Cobalt is integral part of the vitamin(4.5%)  Functions  Transamination & biosynthesis of nutrients like choline,methionine & Folacin  Concerned in synthesis of purines,pyrimidines & proteins
  • 111. Deficiency  Reduced hatchability & embryonic mortality  Anemia, gizzard erosions ,fattiness of heart liver & kidney  Reduction in egg weight  Reduced feed intake, feed efficiency & poor growth of feathers  Nervous disorders
  • 112. Choline  Discovered by Strecker in 1862  Synthesized in liver, highly hygroscopic  Requirement increases with increase levels of dietary protein or fat  Functions  Structural component of cell  Constituent of phospholipids, plays important role in metabolism  Prevents fatty liver by mobilization of fat as lecithin
  • 113. Sources  Fish ,cereal products & oil seed meals
  • 114. Deficiency  Perosis in young chicks  Fatty liver
  • 115. Vitamin c (Ascorbic acid)  1747 James lind ,Scottish Naval Surgeon Discovered  Two forms Reduced form Ascorbic Acid & dehydroxyascorbic acid  Reduced form oxidized to dehydroascorbic acid  Readily destroyed by oxidation  Functions  Collagen synthesis  Electron transfer in the cell  Important role in metabolism of tyrosine  Stimulate phagocytic activity & antibody formation  Synthesis of carnitine  Essential for steroid synthesis
  • 116. Toxicity of vitamin A,D3 & E Vitamin Toxic level Symptoms /lesions A 2,000,000 IU/kg Antagonizes absorption of vitamin D3 & E D3 300,000 IU/kg Hypercalcimia,mine ralization of soft tissue E 40,000 IU/Kg Poor growth ,soft tissue mineralization
  • 117. Specifications For Broiler Feeds(BIS Standards 2007) No Nutrient Unit Pre Starter Starter Finisher 1 Vitamin A Min IU 11000 11000 10000 2 Vitamin D3 Min IU 3000 3000 300 3 Vitamin B1 Min mg 2.5 2.5 2.5 4 Vitamin B2 Min mg 6.0 6.0 6.0 5 Pantothenic acid Min mg 15.0 15.0 15.0 6 Niacin Min mg 40.0 40.0 40.0 7 Biotin Min mg 0.15 0.15 0.15 8 Vitamin B12 Min mg 0.015 0.015 0.015 9 Folic acid Min mg 1.0 1.0 1.0 10 Choline Min mg 500 500 500 11 Vitamin E Min mg 30.0 30.0 30.0 12 Vitamin K Min mg 1.5 1.5 1.5 13 Vitamin B6 Min mg 5.0 5.0 5.0 14 Linoleic acid % 1.1 1.1 1.1
  • 118. Specifications For layer Feeds (BIS Standards 2007) No Nutrient Unit Chick Grower Layer phase I phase II 1 Vitamin A Min IU 9000 8000 8000 8000 2 Vitamin D3 Min IU 1800 1600 1600 1600 3 Vitamin B1 Min mg 2.0 1.5 1.0 1.0 4 Vitamin B2 Min mg 6.0 5.0 5.0 5.0 5 Pantothenic acid Min mg 10.0 9.0 7.0 7.0 6 Niacin Min mg 40.0 20.0 20.0 20.0 7 Biotin Min mg 0.10 0.10 0.10 0.10 8 Vitamin B12 Min mg 0.010 0.008 0.008 0.008 9 Folic acid Min mg 1.0 0.5 0.5 0.5 10 Choline Min mg 500 200 400 400 11 Vitamin E Min mg 15.0 10.0 10.0 10.0 12 Vitamin K Min mg 1.5 1.5 1.5 1.5 13 Vitamin B Min mg 3.0 3.0 3.0 3.0 14 Linoleic acid % 1.0 1.0 1.0 1.0