Kaitlin Thaney discusses making science more open and reproducible through open web technologies. She defines open science as making the entire research process transparent by sharing hypotheses, protocols, data, and analysis. However, current research practices and systems do not fully support open science. Barriers include a lack of access to materials, difficulty publishing negative results, and the "digital skills gap" of many researchers. Promoting a culture of open source through training, community building, and interoperable standards and platforms can help shift practices towards more open and reproducible science at scale.