1. This document provides guidelines for the management of open fractures of the lower limb. It outlines 20 principal recommendations covering topics such as specialist center referral criteria, emergency department management, antibiotic prophylaxis, wound excision timing, debridement, classification, skeletal stabilization, soft tissue reconstruction, and complications.
2. Recommendations include referring complex open fractures to specialist centers, administering IV antibiotics within 3 hours of injury, performing wound excision and debridement within 24 hours, temporarily dressing wounds with VAC or antibiotic beads, stabilizing fractures with external or internal fixation depending on contamination level, and reconstructing soft tissues within 7 days.
3. Factors that increase risk of complications include inadequate debride